What is erythema multiforme?
Erythema multiforme is a skin disorder that's considered to be an allergic reaction
to medicine or an infection. Symptoms are symmetrical, red, raised skin areas that
can appear all over the body. They do seem to be more noticeable on the fingers and
toes. These patches often look like "targets" (dark circles with purple-grey centers).
The skin condition may happen over and over again, and usually lasts for 2 to 4 weeks
Most often, this disorder is caused by the herpes simplex virus. It has also been
associated with Mycoplasma pnemoniae as well as fungal infections. Other causes may
include the following:
What are the symptoms of erythema multiforme?
The following are the most common symptoms of erythema multiforme:
Sudden, red patches and blisters, usually on the palms of hands, soles of feet, and
Flat, round red "targets" (dark circles with purple-grey centers)
The symptoms of erythema multiforme may resemble other skin conditions. Always talk
with your healthcare provider for a diagnosis.
Treatment for erythema multiforme
Specific treatment for erythema multiforme will be discussed with you by your healthcare
provider based on:
Your age, overall health, and medical history
Severity of the condition
Stage of the condition
Your tolerance of specific medicines, procedures, or therapies
Expectations for the course of the condition
Your opinion or preference
Erythema multiforme minor is not very serious and usually clears up with medicine
to control infection or inflammation. However, if a person develops a more severe
form of erythema multiforme (erythema multiforme major), the condition can become
fatal. Erythema multiforme major is also known as Stevens-Johnson syndrome. It is
usually caused by a medicine reaction rather than an infection.
Treatment may include:
It is recommended that if you have symptoms of erythema multiforme, go to your emergency
room or call 911. If a large area of skin is involved, it is an emergency situation.