What is cholecystitis?
Cholecystitis (pronounced ko-luh-sis-TIE-tis) is a redness and swelling (inflammation)
of the gallbladder. It happens when a digestive juice called bile gets trapped in
The gallbladder is a small organ under your liver. It stores bile which is made in
Normally bile drains out of your gallbladder and into your small intestine. If the
bile is blocked, it builds up in your gallbladder. This causes inflammation and can
Cholecystitis can be sudden (acute) or long-term (chronic).
What causes cholecystitis?
Cholecystitis happens when a digestive juice called bile gets trapped in your gallbladder.
In most cases this occurs because lumps of solid material (gallstones) are blocking
a tube that drains bile from the gallbladder.
When gallstones block this tube, bile builds up in your gallbladder. This causes irritation
and pressure in the gallbladder. It can cause swelling and infection.
The gallbladder stores bile. Gallstones are formed in your gallbladder. They are made
Other causes of cholecystitis include:
- Bacterial infection in the bile duct system. The bile duct system is the drainage system that carries bile from your liver and
gallbladder into the first part of your small intestine (the duodenum).
- Tumors of the pancreas or liver. A tumor can stop bile from draining out of your gallbladder.
- Reduced blood supply to the gallbladder. This may happen if you have diabetes.
- Gallbladder sludge. This is a thick material that can’t be absorbed by bile in your gallbladder. The sludge
builds up in your gallbladder. It happens mainly to pregnant women or to people who
have had a very fast weight loss.
Cholecystitis can occur suddenly (acute) or it can be long-term (chronic).
What are the symptoms of cholecystitis?
In most cases an attack of cholecystitis lasts 2 to 3 days. Each person’s symptoms
may vary. Symptoms may include:
- Intense, sudden pain in the upper right part of your belly or abdomen
- Pain (often worse with deep breaths) that spreads to your back or below the right
- Yellowing of the skin and eyes (jaundice)
- Loose, light-colored bowel movements
- Belly bloating
The symptoms of cholecystitis may look like other health problems. Always see your
health care provider to be sure.
How is cholecystitis diagnosed?
Your health care provider will look at your past health and give you a physical exam.
You may also have some blood tests including:
- Complete blood count (CBC). This test measures your white blood cell count. You may have a high white blood cell
count if you have an infection.
- Liver function tests. A group of special blood tests that can tell if your liver is working properly.
You may also have imaging tests, including:
- Ultrasound (also called sonography). This test creates images of your internal organs on a computer screen using high-frequency
sound waves. It is used to see the liver and gallbladder and check blood flow through
- Belly or abdominal X-ray. This test makes pictures of internal tissues, bones, and organs using invisible electromagnetic
- CT scan. A CT scan shows detailed views of any part of the body, including the bones, muscles,
fat, and organs. It is more detailed than a regular X-ray. It uses both X-rays and
computer technology to make horizontal images (often called slices) of the body.
- HIDA scan (cholescintigraphy). This scan checks for any abnormal movements (contractions) of your gallbladder. It
also checks for blocked bile ducts. A radioactive chemical or tracer is shot (injected)
into your vein. The amount of radiation is very small. It is not harmful. It collects
in your liver and flows into your gallbladder. A special scanner watches the tracer
move through your organs. You will take medicine to make your gallbladder contract.
- PTC (percutaneous transhepatic cholangiography). A thin needle is put through your skin and into the bile duct in your liver. A dye
is then shot (injected) through the needle. The dye lets your bile ducts be seen clearly
on the X-rays. A blocked duct will show up on the X-rays.
- ERCP (endoscopic retrograde cholangiopancreatography. This is used to find and treat problems in your liver, gallbladder, bile ducts, and
pancreas. It uses X-ray and a long, flexible tube (endoscope) with a light and camera
at one end. The tube is put into your mouth and throat. It goes down your food pipe
(esophagus), through your stomach, and into the first part of your small intestine
(the duodenum). It then goes into your bile ducts. The inside of these organs can
be seen on a video screen. A dye is put into your bile ducts through the tube. The
dye lets the bile ducts be seen clearly on the X-rays.
How is cholecystitis treated?
You will likely be admitted to a hospital to rest your gallbladder. You may need surgery
to remove your gallbladder.
In the hospital your treatment may include:
- Taking bacteria-fighting medicines (antibiotics) to fight the infection
- Taking fluids and pain medicines by IV (through a vein or intravenously)
- Keeping your stomach empty until your symptoms ease
Your symptoms may get better with this treatment.
But if your cholecystitis is caused by gallstones in your gallbladder, your gallbladder
will need to be removed. Gallbladder removal (called cholecystectomy) is a common
surgery. Your body will work well without your gallbladder. It is not essential for
a healthy life.
You may have surgery done right away. If you are too sick to have surgery, a small
tube may be put through your skin and into your gallbladder. This will drain the bile
and ease your symptoms until you can have surgery.
Other treatment options may include:
- Oral dissolution therapy. Medicines made from bile acid are used to dissolve the stones
- Medicines. These are used to prevent gallstones from forming
- Low-fat diet. When you are allowed to eat food again
What are the complications of cholecystitis?
In some cases cholecystitis can cause other problems including:
- Infection and pus buildup in your gallbladder
- Tissue death in your gallbladder (gangrene)
- Bile duct injury that can affect your liver
- Infection and inflammation of your pancreas (pancreatitis)
- Infection and inflammation of the lining of your belly (peritonitis)
If your gallbladder has not been removed and you have more attacks of cholecystitis,
you may develop long-term (chronic) cholecystitis.
Chronic cholecystitis may not cause any symptoms. But it can damage the walls of your
gallbladder. The walls can become scarred and get thicker. Your gallbladder will start
to get smaller. Over time, it will be less able to store and release bile. You will
need surgery to remove your gallbladder.
When should I call my healthcare provider?
Call your health care provider right away if:
- You have severe belly or abdominal pain that won’t go away
- Your cholecystitis symptoms come back after treatment
Key points about cholecystitis
- Cholecystitis is a redness and swelling (inflammation) of the gallbladder.
- It happens when bile becomes trapped and builds up in the gallbladder.
- In most cases this happens when solid lumps (gallstones) block the tube that drains
bile from the gallbladder.
- In most cases you will be admitted to a hospital.
- Your gallbladder may need to be removed.
Tips to help you get the most from a visit to your health care provider:
- Before your visit, write down questions you want answered.
- Bring someone with you to help you ask questions and remember what your provider tells
- At the visit, write down the names of new medicines, treatments, or tests, and any
new instructions your provider gives you.
- If you have a follow-up appointment, write down the date, time, and purpose for that
- Know how you can contact your provider if you have questions.