Infection and Chemotherapy
The side effects of chemotherapy depend on the type of chemotherapy and the amount
given. Anticipating and managing side effects can help to minimize them and provide
the best possible experience when having chemotherapy.
Infection and chemotherapy
As each person's individual medical profile and diagnosis is different, so is his
or her reaction to treatment. Side effects may be severe, mild, or absent. Be sure
to discuss with your cancer care team the possible side effects of treatment before
the treatment begins.
Many chemotherapy medicines can damage the bone marrow, where blood cells are made.
For most chemotherapy medicines, this effect is temporary and the bone marrow recovers.
White blood cells are the cells that fight many types of infections, which means that
chemotherapy can leave you at risk for infection. The white blood cell most critically
impacted by chemotherapy is called the neutrophil. It fights bacterial infections. The
bacteria that cause most infections are normally found on your skin and in your mouth,
intestines, and genital tract. Sometimes, the source of an infection is unknown. Infections
can happen to people even when they are very careful. If you are fighting infections,
you may be given a medication to boost your white blood cell count after chemotherapy.
How can I help prevent infections?
Most doctors will offer the following suggestions for reducing your risk of infection:
Wash your hands frequently throughout the day, especially before eating, after using
the bathroom, and after touching animals. Use antibacterial hand gel often.
Clean your rectal area gently but thoroughly after each bowel movement. Consult your doctor
if the area becomes irritated or if you develop hemorrhoids.
Avoid people who are sick with contagious illnesses, including a cold, the flu, measles,
Stay away from children who have recently been given "live virus" vaccines, such as
chickenpox, as they may be contagious to people with a low blood cell count. Oral
polio vaccine (OPV) is also a live virus. While it is not currently used in the United
States, it is still used in other countries. Because of that, if you travel internationally,
you should also stay away from children who have recently been given oral polio vaccine.
Avoid accidents and injuries. Be careful not to cut yourself in any way, including
the cuticles of your nails. Use an electric shaver instead of a razor to avoid cutting
yourself while shaving.
Clean cuts and scrapes immediately with warm, soapy water and an antiseptic.
To protect your mouth and gums, brush your teeth after meals and before bedtime.
Do not squeeze or scratch pimples.
Take a warm (not hot) bath, shower, or sponge bath every day. Pat your skin dry; do
not rub it.
Use lotion or oil if your skin becomes dry.
Avoid contact with animal litter boxes and waste. Avoid bird cages and fish and turtle
tanks as well.
Avoid standing water, such as in bird baths, flower vases, or humidifiers.
Wear gloves when gardening or cleaning up after others, especially small children.
Consult your doctor before receiving any type of immunization or shot, such as flu
or pneumonia shots.
Do not eat raw fish, seafood, meat, or eggs.
What are the symptoms of an infection?
If you experience any of the following symptoms, consider it a medical emergency and
contact your doctor right away, before taking any medications. If you are unable to
reach your doctor, go to the emergency room because infections can spread rapidly
in a patient with a low white count. The following are signs and symptoms of a possible
Fever over 100.4°F (38.0°C)
Chills, especially chills that cause your body to shake
Earaches, headaches, or stiff neck
Blisters on the lips or skin
Severe cough or sore throat
Sinus pain or pressure
Loose bowel movements
Frequent rush to urinate or burning with urination
Unusual vaginal discharge or itching
Redness, swelling, or tenderness, especially around a wound, sore, ostomy (an artificial
opening in the abdomen), pimple, rectal area, or catheter site