St. John's Wort
Hypericum Perforatum. Family: Hypericaceae
amber, goatweed, hardhay, hyperici herba, klamath weed, tipton weed
St. John's wort is an herb. It has a yellow flower with 5 petals. It grows in much
of the world. It’s named after St. John the Baptist. This is because it blooms around
his celebration day (June 24). The medicinal part of the plant is made up of the dried
above-ground parts. These include the stem, petals, and flowers.
There are 2 chemicals that play a major role in how it works. These are hypericin
and hyperforin. These and other related compounds are the main active parts. They
may affect serotonin, dopamine, and norepinephrine. These are neurotransmitters in
Medically valid uses
St. John's wort is used to treat mild to moderate depression. But St. John's wort
doesn’t work to treat major or severe depression.
You can apply oily hypericum forms directly to your skin. It can help treat injuries,
muscle pain, and first-degree burns.
There may be benefits that haven't yet been proven through research.
St. John's wort may have these benefits:
Muscle relaxant. It’s used to ease menstrual cramps.
Mild tranquilizer. It may calm mood.
Nerve tonic. It may have a positive effect on the nervous system.
Anti-inflammatory. It may reduce swelling.
Astringent. This action contracts tissues or canals of the body.
Vulnerary. This may heal wounds and swelling.
Antineoplastic. This means it may fight cancer.
Antiviral. It may help fight viral infections. These can include herpes and human immunodeficiency
St. John's wort may be used for nerve pain (neuralgia), anxiety, and tension. It may
also aid in weakness, stress, irritability, and sleeping issues (insomnia). It’s also
claimed to ease the pain due to some conditions. These include sciatica, rheumatoid
arthritis, and menstruation. It may also ease the itching and burning of hemorrhoids
When you apply it topically, St. John's wort may speed healing in certain conditions.
These include bruises, wounds, varicose veins, mild burns, and sunburns.
St. John's wort comes in many forms. These include oil, dried herb, tea, and salve.
It may take 4 to 6 weeks for St. John’s wort to work. If it doesn’t work after this
amount of time, you should consider other treatments.
Side effects, toxicity, and interactions
St. John's wort can change the effects of other medicines and can cause serious side
effects. These medicines include, but are not limited to:
St. John’s wort can keep your body from absorbing iron and other minerals.
In large amounts, St. John's wort can make you more sensitive to the sun. This is
more a risk for people with fair skin. Stay out of the sun as much as you can. When
you must be in the sun, wear sunscreen.
Don’t take large amounts of St. John's wort. Follow the directions on the package.
You shouldn’t take St. John's wort if you have major depression. You also shouldn’t
take it if you’re taking a medicine to treat depression.
People who are pregnant or breastfeeding should talk with their healthcare providers
before taking any supplements.