Hypercalcemia (High Calcium Level in the Blood) and Cancer
What is hypercalcemia?
Hypercalcemia is an abnormally high amount of calcium in the blood. Calcium is a mineral
your body needs that can affect your nerves, muscles, digestive tract, kidneys, and
your heart. When your calcium level gets too high, you may have unusual symptoms.
The calcium level in your blood is controlled by hormones, your kidneys, your gastrointestinal
tract, and bone. Hypercalcemia may happen because cancer has spread to your bones,
which causes calcium to be released. Or the cancer cells may make hormones that affect
the systems controlling the amount of calcium in your blood. Hypercalcemia is not
caused by drinking too much milk or by eating too many dairy products. About 1 in
3 people with cancer have high calcium levels. The symptoms may come on slowly. Or
they may happen in a short period of time.
Certain cancers are more likely to cause hypercalcemia. These include lung cancer,
breast cancer, kidney cancer, head and neck cancers, gastrointestinal cancers, multiple
myeloma, and leukemia.
What are the symptoms of hypercalcemia?
Symptoms of hypercalcemia can be a lot like symptoms of other health problems and
medicine side effects. You and your loved ones should know which signs and symptoms
might mean that your calcium level is getting too high.
It's important to let your healthcare provider know if you have any of the following,
especially if they're different from the way you usually feel:
Severe symptoms include:
Changes in the calcium level in your blood are linked to the cancer. So the best way
to control the calcium is to treat the cancer itself. Your healthcare provider will
talk with you about this.
Some people have symptoms when the calcium level is only slightly high. Others may
not have symptoms until the level is extremely high. Medicines can be used to help
control your calcium level—even if the cancer is not being treated.
If your calcium level is high and you're having many problems, you may need to be
in the hospital for a short period of time. If it is only mildly high, you might be
able to control it at home. The decision of when to treat hypercalcemia is often based
on your symptoms, not your blood calcium level.
If you have mildly high calcium levels and few or no symptoms, treatment may include
You may need to drink more fluids to help your kidneys take calcium out of your blood.
You may have fluids put right into your blood through a vein (IV) if you can't drink
Your calcium levels and symptoms will be closely watched.
For higher calcium levels, or if you are having symptoms, you may need to stay in
the hospital. You can expect the following:
Extra fluids will be given into your blood through a vein (IV).
You may be given calcium-controlling medicines or steroids. These are used to stop
bone from breaking down and releasing calcium.
You may have to take a hormone called calcitonin. It's used to decrease calcium release
from your bones and increase calcium removal in your kidneys.
You will have frequent blood draws. These will be done to check your levels of calcium
and other chemicals.
If you have kidney failure, you may need dialysis.
Here is what to expect:
Blood draws may be needed.
Drink plenty of fluid daily (unless your healthcare provider tells you not to).
Take medicines as directed.
Tell your healthcare provider right away if you have any symptoms or symptoms of hypercalcemia
that get worse.