Malignant Mesothelioma: Tests After Diagnosis
After a diagnosis of mesothelioma, you’ll likely need more tests. These tests help
your healthcare team learn more about the cancer and your overall health. The results
help your healthcare providers decide the best ways to treat the cancer. For instance,
scans can show if it has grown into nearby areas or spread to other parts of your
body. This helps your provider figure out if surgery may be a choice. If you have
any questions about these or other tests, talk with your healthcare team.
The tests you may have include:
Imaging tests
CT scan
During a CT scan , X-rays are used to scan part of your body to create detailed 3-D
pictures of your insides. You may have this done on your chest or belly (abdomen).
These pictures help your healthcare provider see where the cancer is. They can also
show if it has spread to nearby organs or lymph nodes, or to other parts of your body.
To have the test, you lie still on a narrow table as it slowly slides through the
center of the doughnut-shaped CT scanner. A computer uses many X-rays to create pictures.
A CT scan doesn't hurt. You may be asked to hold your breath a few times during the
scan. Often, an IV contrast-agent (contrast dye) is put into a vein for the scan.
This helps details show up better. The IV contrast and contrast taken by mouth will
slowly pass through your body and exit through your urine or bowel movements.
MRI
An MRI uses powerful magnets, radio waves, and a computer to create very detailed
pictures of the inside of your body. An MRI is sometimes used to show exactly how
much and where the cancer is. This can help tell if surgery might be a choice.
An MRI is not painful. It can take up to an hour to do. Often an IV contrast agent
called gadolinium will be put into a vein before getting the scan. During the scan,
you’ll need to lie still on a narrow table that slides into a long, narrow tube. This
makes some people feel claustrophobic. If you've had problems with enclosed spaces
in the past, tell your healthcare provider before the MRI. You may be given a sedative
medicine to help you stay calm during the test. If you get a sedative, you’ll need
to allow for time after the test for its effect to wear off. Newer, more open MRI
machines can sometimes be used instead. But the images may not be as sharp. The equipment
makes loud banging noises during the scan. You can ask for earplugs if you think the
noise will bother you.
Because the test uses powerful magnets, you won’t be allowed to have anything metal
in the room. Even eyeglasses and ballpoint pens can be dangerous when the magnets
are turned on. Be sure to tell your providers if you have any kind of metal implant
in your body to be sure an MRI is safe for you.
PET scan
This test may be used to look for spread of the cancer to lymph nodes or to other
parts of your body. A PET scan can also be helpful if your healthcare provider thinks
the cancer may have spread but doesn't know where. Because it scans your whole body,
a PET scan might be done instead of doing multiple X-rays of different parts of your
body. The picture isn’t as detailed as a CT scan. But it can be done along with a
CT scan to look for cancer.
For this test, a mildly radioactive sugar (radiotracer) is put into a vein before
the scan. Cancer cells absorb more of this sugar than normal cells. To have the scan,
you’ll need to lie still on a table as it slowly slides through the doughnut-shaped
PET scanner. This machine takes pictures that show where the sugar has collected in
your body. These spots might be cancer. A PET scan is painless.
Some imaging centers use a PET/CT scanner machine. This machine does a PET and CT
scan at the same time. The healthcare provider can compare high radioactive areas
on the PET scan with more detailed pictures on the CT scan.
Mediastinoscopy and other staging surgeries
Imaging tests can help show the extent of the cancer. But they might not always show
all of the cancer. Surgery is often the best way to treat mesothelioma, if it can
be done. But this is a major surgery. So it’s important to know ahead of time if all
of the cancer can be removed.
If your healthcare provider thinks surgery might be a choice, a less complex, staging
surgery might be done first to help be sure. These surgeries use thin, lighted tubes
called scopes to look inside your body. This allows your provider to look for areas
of cancer that imaging tests might have missed. It's not done to treat the cancer.
A mediastinoscopy is an example of a staging surgery. To do it, a thin, tube with
a light and lens at the end is put into your chest through a small cut in the skin
above your breastbone. This tube is called a mediastinoscope. It's slid down behind
your breastbone to see organs, tissues, and lymph nodes there. A staging laparoscopy is
another example. In this test, a small, lighted tube with a tiny camera on the end
(called a laparoscope) is put in through a cut in the skin over your belly (abdomen).
This is done to look at the lining of the inner part of your belly and the lining
that covers your intestines and other organs.
If your provider sees changes that might be cancer, tools can be used through the
scope to take out tiny pieces of tissue. These are sent to a lab to be tested. (This
is called a biopsy.)
Working with your healthcare provider
Your healthcare provider will talk with you about which tests you'll have. Make sure
to get ready for the tests as instructed. Ask questions and talk about any concerns
you have.