What is polycythemia vera?
Polycythemia vera is a rare blood disorder in which there is an increase in all blood
cells, particularly red blood cells. The increase in blood cells makes your blood
thicker. This can lead to strokes or tissue and organ damage.
What causes polycythemia vera?
Polycythemia vera is caused by a genetic change (mutation) that develops during your
lifetime. It is not an inherited genetic disorder. In most cases it is not known why
What are the symptoms of polycythemia vera?
When you have more blood and it is thicker than normal, problems can occur. Each person’s
symptoms may vary. Symptoms may include:
- Lack of energy (fatigue) or weakness
- Shortness of breath and trouble breathing while lying down
- Vision problems, such as double vision, blurred vision, and blind spots
- Inability to concentrate
- Night sweats
- Face and becomes red and warm (flushed)
- Bleeding gums
- Too much menstrual bleeding
- Coughing up blood
- Itchy skin (often after a hot bath)
- High blood pressure
These symptoms may look like other blood disorders or health problems. Always see
your healthcare provider for a diagnosis.
How is polycythemia vera diagnosed?
Your healthcare provider will take your medical history and give you a physical exam.
Your provider may also do blood tests. These tests will check the increased number
of red blood cells in your body. They will also check if there are other conditions
that could cause your higher red blood cell count.
How is polycythemia vera treated?
Your healthcare provider will figure out the best treatment based on:
- Your age, overall health, and medical history
- How sick you are
- How well you handle certain medicines, treatments, or therapies
- If your condition is expected to get worse
- What you would like to do
Treatment may include:
- Phlebotomy. This procedure removes blood from your body. At first this must be done often, such
as every week. Once enough blood has been removed to reduce your body's iron stores
(needed to make blood quickly), you will not need this done as often.
- Certain medicines, including chemotherapy. The medicines help to stop your bone marrow from making too many blood cells. They
also keep your blood flow and blood thickness closer to normal.
What are the complications of polycythemia vera?
Polycythemia vera can be fatal if not diagnosed and treated. It can cause blood clots
resulting in a heart attack, stroke, or pulmonary embolism. Liver and spleen enlargement
are other possible complications.
Living with polycythemia vera
There is no cure for polycythemia vera, but proper treatment can help to reduce or
delay any problems. Work with your healthcare provider to create a treatment plan
that fits your needs. You should also be physically active in order to increase your
heart rate and improve your blood flow.
Other ways to improve your blood flow include:
- Stretching your legs and ankles
- Wearing warm gloves and socks during cold weather
- Avoiding extreme heat
- Drinking plenty of water
You should also avoid situations in which you could be hurt, and check your feet for
Key points about polycythemia vera
- Polycythemia vera is a rare blood disorder in which there is an increase in all blood
cells, particularly red blood cells.
- The increase in blood cells makes the blood thicker.
- Thick blood can lead to strokes or tissue and organ damage.
- Symptoms include lack of energy (fatigue) or weakness, headaches, dizziness, shortness
of breath, visual disturbances, nose bleeds, bleeding gums, heavy menstrual periods,
- Treatment may include medicines and phlebotomy, a procedure that removes extra blood
from your body.
Tips to help you get the most from a visit to your healthcare provider:
- Know the reason for your visit and what you want to happen.
- Before your visit, write down questions you want answered.
- Bring someone with you to help you ask questions and remember what your provider tells
- At the visit, write down the name of a new diagnosis, and any new medicines, treatments,
or tests. Also write down any new instructions your provider gives you.
- Know why a new medicine or treatment is prescribed, and how it will help you. Also
know what the side effects are.
- Ask if your condition can be treated in other ways.
- Know why a test or procedure is recommended and what the results could mean.
- Know what to expect if you do not take the medicine or have the test or procedure.
- If you have a follow-up appointment, write down the date, time, and purpose for that
- Know how you can contact your provider if you have questions.