Emily Barrett, Ph.D.
Obstetrics & GynecologyHow environmental exposures across the life course affect reproductive function
Danielle Benoit, Ph.D.
Deborah Cory-Slechta, Ph.D.
Environmental MedicineDefining the impact of environmental chemicals (e.g., metals and air pollution) on brain development and behavior, with emphasis on attributable risk to neurodevelopmental disorders.
Philip Davidson, Ph.D.
PediatricsAging and Developmental Disabilities; Behavior Disorders; and Neurotoxicants and Development.
Lisa A. DeLouise, Ph.D., M.P.D.
DermatologyUnderstanding the toxicological and biochemical properties of nanomaterial interactions with skin and the immune system; develop in vivo models to investigate nanoparticle skin penetration mechanisms, and develop novel biosensors to improve transdermal drug delivery and tissue engineering approaches.
Alison Elder, Ph.D.
Environmental MedicineDefining the impact of inhaled ambient and workplace nano-/ultrafine particle-containing aerosols on the lung, cardiovascular system, and central nervous system, and defining the toxicological properties of the particles that are associated with a response.
Jacob N. Finkelstein, Ph.D.
PediatricsDelineating the role of alveolar epithelium in modulating the pulmonary injury response to physiological and toxicological stimuli, including oxidant induced signaling in the pulmonary epithelium and macrophages, and epithelial production of mediators that regulate inflammatory functions of macrophages.
Mark Frampton, M.D.
MedicineEffects of particle exposure on lung function, airway inflammation, and cardiovascular function.
Steve Georas, M.D.
MedicineDefining the role of environmental exposures on innate and adaptive immunity in asthma and other chronic lung diseases, with an emphasis on how particulate matter and endocrine disruptors act as risk factors.
Jill Halterman, M.D., M.P.H.
PediatricsAsthma and Improving quality of care
Jill Halterman Lab
Elaine Hill, Ph.D.
Public Health SciencesEarly origins research, linking in utero environment to later life health and educational attainment
Brent Johnson, Ph.D.
Biostatistics & Computational BiologyStatistical methodology for biomedical and public health applications including semi-parametric and non-parametric methods in missing data problems, measurement error, and survival analysis.
Todd A. Jusko, Ph.D.
Public Health SciencesDefining the impact of environmental chemicals on immunity and immune-mediated diseases and as a mechanism for susceptibility to other disease outcomes, such as neurobehavioral disorders.
Katrina Korfmacher, Ph.D.
Environmental MedicineCommunity outreach and engagement, role of science in public decision-making
B. Paige Lawrence, Ph.D.
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Environmental MedicineDelineating mechanisms by which environmental exposures during different life stages alter immune function; discovering how environmental factors modulate epigenetic programming of the developing immune system, and the consequences of these changes on susceptibility to infectious, allergic, or autoimmune disease later in life.
Tanzy Love, Ph.D.
Biostatistics & Computational BiologyFinding hidden groups and their meanings; latent variable modeling; methods and techniques for Bayesian solutions.
Mahin Maines, Ph.D.
Biochemistry & BiophysicsHeme oxygenases and second messenger gases: CO and NO.
Thomas Mariani, Ph.D.
PediatricsSystems Biology of Lung Development and Disease
Dina G. Markowitz, Ph.D.
Margot Mayer-Pröschel, Ph.D.
Biomedical GeneticsDeciphering the impact of nutritional, toxicological, viral, and genetic insults, singly and in combination, on mammalian brain development and disease later in life.
Robert A. Mooney, Ph.D.
Pathology & Laboratory MedicineBone diseases, particularly osteoporosis and osteoarthritis
Gary J. Myers, M.D.
NeurologyEnvironmental toxins, specifically mercury; methyl mercury exposure
Mark Noble, Ph.D.
Biomedical GeneticsDiscovering new treatments for afflictions that lack satisfactory therapies, and to better understand the toxicity of currently used medicines; studies span normal and pathological cell function, with focus on stem and progenitor cells.
M. Kerry O'Banion, M.D., Ph.D.
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NeuroscienceDefining neuro-inflammatory processes that contribute to pathology and disease progression in Alzheimer's disease, as well as late CNS effects following radiation exposure
Michael A. O'Reilly, Ph.D.
PediatricsUnderstanding how an aberrant oxygen environment at birth disrupts development of the lung and heart, leading to persistent functional changes over the lifespan.
David Oakes, Ph.D.
Günter Oberdörster, D.V.M., Ph.D.
Environmental MedicineBiokinetics, Effects and Mechanisms of Inhaled Micro- and Nano- Particles: Dosimetry, Risk Extrapolation and Risk Assessment
Richard Phipps, Ph.D.
Environmental MedicineInvestigating how environmental factors shape diseases involving immune and inflammatory components, including platelets, B cells, and lipid mediators, defining abnormal inflammatory and wound healing responses in the eye and lung, delineating molecular signaling in fibroblasts.
Gloria S. Pryhuber, M.D.
PediatricsDelineating multifactorial causes of respiratory morbidity in infants and young children, including environmental exposures on lung development, microbial infection and dysbiosis, and pulmonary immune responses; levering unique human lung and immune cell repositories that support the in vitro study of mechanisms of toxicity of environmental agents.
J. Edward Puzas, Ph.D.
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OrthopaedicsDeciphering the molecular signals that govern osteoporosis and arthritis, as well as cellular changes that contribute to difficulties such as the loosening of artificial joints, including defining how environmental toxins such as lead, play a role in bone and joint diseases.
Arshad Rahman, Ph.D.
PediatricsDetermining how exogenous agents change lung microvasculature permeability, leading to pulmonary inflammation.
Arshad Rahman Lab
Irfan Rahman, Ph.D.
Environmental MedicineDefining effects of inhaled environmental tobacco smoke, e-cigarettes, flavoring chemicals, and water pipe smoke toxicants on mitochondrial function, exosomes, and epigenetic chromatin modifiers in lung cell senescence, oxidative stress, and inflammation.
Irfan Rahman Lab
Matthew D. Rand, Ph.D.
Environmental MedicineMechanisms of toxicity of the environmental contaminant and neurotoxicant methylmercury (MeHg), defining MeHg effects on early life development of neural and muscular systems at the molecular, cellular, and organismal levels using invertebrate and mammalian models, and detailed characterization of MeHg metabolism and elimination kinetics in humans.
David Rich, Sc.D., M.P.H.
Public Health SciencesExamining associations between air pollution and cardiopulmonary and pregnancy outcomes, validating biomarkers that may explain associations and developing spatial-temporal models of air pollution to enable field studies of these biomarkers and clinical outcomes associated with residential air pollution exposures.
Patricia Sime, M.D.
MedicineConducting clinical and translational toxicology research focusing on the lung, from studies of silica and radiation in lung fibrosis, to the effects of biomass and cigarette smoke exposure on lung inflammation and resolution pathways, to identifying key pathophysiologic pathways and developing novel therapeutics for lung inflammation and fibrosis.
Martha Susiarjo, Ph.D.
Environmental MedicineStudying epigenetic mechanisms underlying environment-induced adverse pregnancy and developmental outcomes, including how endocrine-disrupting chemicals change maternal health, mammalian reproduction, and the expression and function of imprinted genes.
Sally Thurston, Ph.D.
Biostatistics & Computational BiologyBayesian inference, modeling multiple outcomes, correction for measurement error bias, informative prior specification, latent variable models, and environmental health applications.
David Topham, Ph.D.
Microbiology & ImmunologyConducting clinical and translational research on respiratory pathogens, immunity, and infectious disease, including the study of environmental factors that affect immune responses to influenza and vaccination, seeking new approaches to enhance immunity, reduce pathology, and prevent disease.
Program for Advanced Immune Bioimaging
Mark Utell, M.D.
Edwin Van Wijngaarden, Ph.D., M.Sc.
Public Health SciencesDefining influences of environmental exposures, in particular toxic metals, on cognitive outcomes in children and adults.
Gene Watson, D.D.S., Ph.D.
Eastman Institute for Oral Health
Jacqueline Patricia Williams, Ph.D.
Environmental MedicineDiscovering the effects of high (therapeutic) and low (environmentally-relevant) doses of radiation and their interactions with other toxic elements, such as commonly encountered infections, and better understanding differential effects of radiation in adults versus children.
Jacqueline Williams Lab
Wojciech Zareba, M.D., Ph.D.
MedicineRisk stratification of cardiac death and on clinical usefulness and prognostic significance of ECG parameters
Michael John Zuscik, Ph.D.
OrthopaedicsDefining the impact of obesity on bone repair, the molecular and cellular impact of chemical substances, including lead and benzo(a)pyrene, elucidating the molecular basis for deleterious effects of cigarette smoke on bone fracture healing, and uncovering basic signaling pathways involved with Pb-induced bone loss.