URMC / Labs / Brown Lab / Publications Recent Publications Ramirez GProctor ARJung KWWu TTHan SAdams RRRen JByun DKMadden KSBrown EBFoster THFarzam PDurduran TChoe R (2016 Sep 1). Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy. Biomedical optics express. Herr MMMohile NAvan Wijngaarden EBrown EBRich DQ (2016 Jun 11). Antidepressant use and risk of central nervous system metastasis. Journal of neuro-oncology. Madden KS (2016 Apr 24). Sympathetic neural-immune interactions regulate hematopoiesis, thermoregulation and inflammation in mammals. Developmental and comparative immunology. Clarke BLBrown EMCollins MTJüppner HLakatos PLevine MAMannstadt MMBilezikian JPRomanischen AFThakker RV (2016 Mar 4). Epidemiology and Diagnosis of Hypoparathyroidism. The Journal of clinical endocrinology and metabolism. Szpunar MJBelcher EKDawes RPMadden KS (2016 Mar). Sympathetic innervation, norepinephrine content, and norepinephrine turnover in orthotopic and spontaneous models of breast cancer. Brain, behavior, and immunity. Van Hove AHBurke KAntonienko EBrown EBenoit DS (2015 Nov 10). Enzymatically-responsive pro-angiogenic peptide-releasing poly(ethylene glycol) hydrogels promote vascularization in vivo. Journal of controlled release : official journal of the Controlled Release Society. Vanden Berghe THulpiau PMartens LVandenbroucke REVan Wonterghem EPerry SWBruggeman IDivert TChoi SMVuylsteke MShestopalov VILibert CVandenabeele P (2015 Jul 21). Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice. Immunity. Van Hove AHAntonienko EBurke KBrown EBenoit DS (2015 Jul 7). Temporally Tunable, Enzymatically Responsive Delivery of Proangiogenic Peptides from Poly(ethylene glycol) Hydrogels. Advanced healthcare materials. Kottmann RMSharp JOwens KSalzman PXiao GQPhipps RPSime PJBrown EBPerry SW (2015 May 27). Second harmonic generation microscopy reveals altered collagen microstructure in usual interstitial pneumonia versus healthy lung. Respiratory research. Burke KADawes RPCheema MKVan Hove ABenoit DSPerry SWBrown E (2015 May). Second-harmonic generation scattering directionality predicts tumor cell motility in collagen gels. Journal of biomedical optics. Haynes-Gimore NBanach MBrown EDawes REdholm ESKim MRobert J (2015 Jan 16). Semi-solid tumsor model in Xenopus laevis/gilli cloned tadpoles for intravital study of neovascularization, immune cells and melanophore infiltration. Developmental biology. Bouta EMLi JJu YBrown EBRitchlin CTXing LSchwarz EM (2015 Jan 15). The Role of the Lymphatic System in Inflammatory-Erosive Arthritis. Seminars in cell & developmental biology. Huang CNess VPYang XChen HLuo JBrown EBZhang X (2015 Jan 15). Spatiotemporal Analyses of Osteogenesis and Angiogenesis via Intravital Imaging in Cranial Bone Defect Repair. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Burke KSmid MDawes RPTimmermans MASalzman Pvan Deurzen CHBeer DGFoekens JABrown E (2015). Using second harmonic generation to predict patient outcome in solid tumors. BMC cancer. Bouta EMWood RWBrown EBRahimi HRitchlin CTSchwarz EM (2014 Mar 15). In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice. The Journal of physiology. Sullivan KDMajewska AKBrown EB (2015). Single- and two-photon fluorescence recovery after photobleaching. Cold Spring Harbor protocols. Shapovalov YZettel MSpielman SCAmico-Ruvio SAKelly EASipe GODickerson IMMajewska AKBrown EB (2014). Fluoxetine modulates breast cancer metastasis to the brain in a murine model. BMC cancer. Szpunar MJBurke KADawes RPBrown EBMadden KS (2013 Dec). The antidepressant desipramine and α2-adrenergic receptor activation promote breast tumor progression in association with altered collagen structure. Cancer prevention research (Philadelphia, Pa.). Arendt OSchwaller BBrown EBEilers JSchmidt H (2013 Aug 15). Restricted diffusion of calretinin in cerebellar granule cell dendrites implies Ca²⁺-dependent interactions via its EF-hand 5 domain. The Journal of physiology. Burke RMMadden KSPerry SWZettel MLBrown EB (2013 Aug). Tumor-associated macrophages and stromal TNF-α regulate collagen structure in a breast tumor model as visualized by second harmonic generation. Journal of biomedical optics. Chen THilton MJBrown EBZuscik MJAwad HA (2013 May). Engineering superficial zone features in tissue engineered cartilage. Biotechnology and bioengineering. Madden KSSzpunar MJBrown EB (2013 Mar). Early impact of social isolation and breast tumor progression in mice. Brain, behavior, and immunity. Burke KTang PBrown E (2013 Mar). Second harmonic generation reveals matrix alterations during breast tumor progression. Journal of biomedical optics. Madden KSZettel MLMajewska AKBrown EB (2013 Mar). Brain tumor imaging: live imaging of glioma by two-photon microscopy. Cold Spring Harbor protocols. Madden KSZettel MLMajewska AKBrown EB (2013 Mar). Brain tumor imaging: imaging brain metastasis using a brain-metastasizing breast adenocarcinoma. Cold Spring Harbor protocols. Thyagarajan SMadden KSBoehm GWStevens SYFelten DLBellinger DL (2013). L-Deprenyl reverses age-associated decline in splenic norepinephrine, interleukin-2 and interferon-γ production in old female F344 rats. Neuroimmunomodulation. Perry SWSchueckler JMBurke KArcuri GLBrown EB (2013). Stromal matrix metalloprotease-13 knockout alters Collagen I structure at the tumor-host interface and increases lung metastasis of C57BL/6 syngeneic E0771 mammary tumor cells. BMC cancer. Perry SWBurke RMBrown EB (2012 Feb). Two-photon and second harmonic microscopy in clinical and translational cancer research. Annals of biomedical engineering. Madden KSSzpunar MJBrown EB (2011 Dec). β-Adrenergic receptors (β-AR) regulate VEGF and IL-6 production by divergent pathways in high β-AR-expressing breast cancer cell lines. Breast cancer research and treatment. Bouta EMWood RWPerry SWBrown EBRitchlin CTXing LSchwarz EM (2011 Dec). Measuring intranodal pressure and lymph viscosity to elucidate mechanisms of arthritic flare and therapeutic outcomes. Annals of the New York Academy of Sciences. Sullivan KDBrown EB (2011 May). Multiphoton fluorescence recovery after photobleaching in bounded systems. Physical review. E, Statistical, nonlinear, and soft matter physics. ThyagaRajan SMadden KSTeruya BStevens SYFelten DLBellinger DL (2011 Apr). Age-associated alterations in sympathetic noradrenergic innervation of primary and secondary lymphoid organs in female Fischer 344 rats. Journal of neuroimmunology. Perry SWNorman JPBarbieri JBrown EBGelbard HA (2011 Feb). Mitochondrial membrane potential probes and the proton gradient: a practical usage guide. BioTechniques. Sullivan KBrown E (2011 Jan 01). Diffusion and multi-photon fluorescence recovery after photobleaching in bounded systems Physical review E. In Press. Perry SNorman JBarbieri JBrown EGelbard H (2011 Jan 01). Mitochondrial membrane potential probes and the proton gradient: a practical usage guide BioTechniques. In Press. Perry SWBarbieri JTong NPolesskaya OPudasaini SStout ALu RKiebala MMaggirwar SBGelbard HA (2010 Oct 20). Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax. The Journal of neuroscience : the official journal of the Society for Neuroscience. Kozai TDMarzullo TCHooi FLanghals NBMajewska AKBrown EBKipke DR (2010 Aug). Reduction of neurovascular damage resulting from microelectrode insertion into the cerebral cortex using in vivo two-photon mapping. Journal of neural engineering. Han XBrown E (2010 May 10). Measurement of the ratio of forward-propagating to back-propagating second harmonic signal using a single objective. Optics express. Sullivan KDBrown EB (2010). Measuring diffusion coefficients via two-photon fluorescence recovery after photobleaching. Journal of visualized experiments : JoVE. Li JSullivan KBrown EAnthamatten M (2010 Jan 01). Thermally activated diffusion in reversibly associating polymers Soft matter. Sullivan KBrown E (2010 Jan 01). Measuring Diffusion Coefficients via Two-Photon Fluorescence Recovery After Photobleaching Journal of visualized experiments. Chauhan VPLanning RMDiop-Frimpong BMok WBrown EBPadera TPBoucher YJain RK (2009 Jul 8). Multiscale measurements distinguish cellular and interstitial hindrances to diffusion in vivo. Biophysical journal. Sullivan KDSipprell WHBrown EBBrown EB (2009 Jun 17). Improved model of fluorescence recovery expands the application of multiphoton fluorescence recovery after photobleaching in vivo. Biophysical journal. Han XBurke RMZettel MLTang PBrown EB (2008 Feb 4). Second harmonic properties of tumor collagen: determining the structural relationship between reactive stroma and healthy stroma. Optics express. Schmidt HArendt OBrown EBSchwaller BEilers J (2007 Feb). Parvalbumin is freely mobile in axons, somata and nuclei of cerebellar Purkinje neurones. Journal of neurochemistry. Tyrrell JAMahadevan VTong RTBrown EBJain RKRoysam B (2005 Nov). A 2-D/3-D model-based method to quantify the complexity of microvasculature imaged by in vivo multiphoton microscopy. Microvascular research. Stroh MZimmer JPDuda DGLevchenko TSCohen KSBrown EBScadden DTTorchilin VPBawendi MGFukumura DJain RK (2005 Jun). Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo. Nature medicine. Duda DGFukumura DMunn LLBooth MFBrown EBHuang PSeed BJain RK (2004 Sep 1). Differential transplantability of tumor-associated stromal cells. Cancer research. Brown EBBoucher YNasser SJain RK (2004 May). Measurement of macromolecular diffusion coefficients in human tumors. Microvascular research. Garkavtsev IKozin SVChernova OXu LWinkler FBrown EBarnett GHJain RK (2004 Mar 18). The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis. Nature.