Honors & News
February 11, 2016
Scientists at the University of Rochester School of Medicine and Dentistry have discovered a way to make a nasal spray flu vaccine safer for those who are at greatest risk of catching the flu, particularly infants under the age of 2. The work is early and a long way from being applied in people, but offers promise for a vaccine that could better protect the most vulnerable.
- A single mutation at PB1 residue 319 dramatically increases the safety of PR8 LAIV in a murine model without compromising vaccine efficacy.J Virol. (2015 Dec 16).
- Leucine-rich repeat kinase 2 modulates neuroinflammation and neurotoxicity in models of human immunodeficiency virus 1-associated neurocognitive disorders.J Neurosci. 35, 5271-83. (2015 Apr 01).
- Development of a mouse-adapted live attenuated influenza virus that permits in vivo analysis of enhancements to the safety of live attenuated influenza virus vaccine.J Virol. 89, 3421-6. (2015 Mar 01).