Taylor Moon and Kyle Koster Receive Awards at Local Meetings
Thursday, October 22, 2015
Congratulations to Taylor Moon and Kyle Koster for their award-winning presentations at two local scientific meetings. Taylor received the "Excellence in Scientific Presentation" award at the Department of Microbiology and Immunology Retreat on October 6th 2015. Kyle received the second place award for his poster at the American Physician Scientists Association Northeast Regional Meeting in Syracuse October 17th 2015. Taylor and Kyle are Microbiology and Immunology doctoral students in the Elliott Lab in the Center for Vaccine Biology and Immunology.
Elliott Lab Awarded Grant To Study The Role Of Efferocytosis In Resolving Inflammation
Wednesday, April 15, 2015
The transition of the immune response from inflammation to resolution is critical for the restoration of tissue function following injury or infection. Most inflamed tissues contain large numbers of dead and dying cells, and the phagocytic clearance of these cells (a process termed "efferocytosis") by tissue-resident macrophages plays an important but poorly understood role in driving pro-resolution immune responses. CD73, the main adenosine-generating ecto-enzyme on leukocytes, exerts a wide range of immunomodulatory effects, but its role in efferocytosis is not known. The laboratory of Michael R. Elliott has been awarded a five-year grant from the National Institutes of Health to study the molecular mechanisms and physiologic importance of the CD73 pathway in mediating efferocytosis-dependent immune suppression in inflamed tissues (R01AI114554). Identifying the molecular pathways that link cell clearance to inflammation could contribute to the development of novel therapeutic strategies to affect beneficial immune responses in a wide range of inflammation-related disorders.