Publications Billroth-MacLurg ACFord JRosenberg AMiller JFowell DJ (2016 Aug 10). Regulatory T Cell Numbers in Inflamed Skin Are Controlled by Local Inflammatory Cues That Upregulate CD25 and Facilitate Antigen-Driven Local Proliferation. Journal of immunology (Baltimore, Md. : 1950). Batchu SNHughson AWadosky KMMorrell CNFowell DJKorshunov VA (2016 Jun 30). Role of Axl in T-Lymphocyte Survival in Salt-Dependent Hypertension. Arteriosclerosis, thrombosis, and vascular biology. Gaylo AOverstreet MGFowell DJ (2016). Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis. Journal of visualized experiments : JoVE. Misra RSShah SFowell DJWang HScheible KMisra SKHuyck HWyman CPRyan RMReynolds AMMariani TJKatzman PJPryhuber GS (2015 May). Preterm cord blood CD4⁺ T cells exhibit increased IL-6 production in chorioamnionitis and decreased CD4⁺ T cells in bronchopulmonary dysplasia. Human immunology. Shi GField DJKo KATure SSrivastava KLevy SKowalska MAPoncz MFowell DJMorrell CN (2014 Feb). Platelet factor 4 limits Th17 differentiation and cardiac allograft rejection. The Journal of clinical investigation. Overstreet MGGaylo AAngermann BRHughson AHyun YMLambert KAcharya MBillroth-Maclurg ACRosenberg AFTopham DJYagita HKim MLacy-Hulbert AMeier-Schellersheim MFowell DJ (2013 Sep). Inflammation-induced interstitial migration of effector CD4⁺ T cells is dependent on integrin αV. Nature immunology. Batchu SNHughson AGerloff JFowell DJKorshunov VA (2013 Aug). Role of Axl in early kidney inflammation and progression of salt-dependent hypertension. Hypertension. Lazarski CAFord JKatzman SDRosenberg AFFowell DJ (2013). IL-4 attenuates Th1-associated chemokine expression and Th1 trafficking to inflamed tissues and limits pathogen clearance. PloS one. Hyun YMSumagin RSarangi PPLomakina EOverstreet MGBaker CMFowell DJWaugh RESarelius IHKim M (2012 Jul 2). Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels. The Journal of experimental medicine. Huang YHSojka DKFowell DJ (2012 Feb 1). Cutting edge: Regulatory T cells selectively attenuate, not terminate, T cell signaling by disrupting NF-κB nuclear accumulation in CD4 T cells. Journal of immunology (Baltimore, Md. : 1950). Mock DJHollenbaugh JADaddacha WOverstreet MGLazarski CAFowell DJKim B (2012). Leishmania induces survival, proliferation and elevated cellular dNTP levels in human monocytes promoting acceleration of HIV co-infection. PLoS pathogens. Sojka DKFowell DJ (2011 Nov 8). Regulatory T cells inhibit acute IFN-γ synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10. Proceedings of the National Academy of Sciences of the United States of America. Singleton KLGosh MDandekar RDAu-Yeung BBKsionda OTybulewicz VLAltman AFowell DJWülfing C (2011 Oct 4). Itk controls the spatiotemporal organization of T cell activation. Science signaling. Hughson ABromberg IJohnson BQuataert SJospe NFowell DJ (2011 Aug). Uncoupling of proliferation and cytokines from suppression within the CD4+CD25+Foxp3+ T-cell compartment in the 1st year of human type 1 diabetes. Diabetes. Morales-Tirado VSojka DKKatzman SDLazarski CAFinkelman FDUrban JFFowell DJ (2010 Apr 29). Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function. Blood. Sahu NMorales JLFowell DAugust A (2010). Modeling susceptibility versus resistance in allergic airway disease reveals regulation by Tec kinase Itk. PloS one. Sojka DKLazarski CAHuang YHBromberg IHughson AFowell DJ (2009 Dec). Regulation of immunity at tissue sites of inflammation. Immunologic research. Sojka DKHughson AFowell DJ (2009 Jun). CTLA-4 is required by CD4+CD25+ Treg to control CD4+ T-cell lymphopenia-induced proliferation. European journal of immunology. Fowell DJ (2009 Apr). Signals for the execution of Th2 effector function. Cytokine. Lazarski CAHughson ASojka DKFowell DJ (2008 Oct 17). Regulating Treg cells at sites of inflammation. Immunity. Sojka DKHuang YHFowell DJ (2008 May). Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target. Immunology. Katzman SDFowell DJ (2008 Feb). Pathogen-imposed skewing of mouse chemokine and cytokine expression at the infected tissue site. The Journal of clinical investigation. Zhao XZheng BHuang YYang DKatzman SChang CFowell DZeng WP (2007 Dec 15). Interaction between GATA-3 and the transcriptional coregulator Pias1 is important for the regulation of Th2 immune responses. Journal of immunology (Baltimore, Md. : 1950). Au-Yeung BBFowell DJ (2007 Jul 1). A key role for Itk in both IFN gamma and IL-4 production by NKT cells. Journal of immunology (Baltimore, Md. : 1950). Kobie JJShah PRYang LRebhahn JAFowell DJMosmann TR (2006 Nov 15). T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine. Journal of immunology (Baltimore, Md. : 1950). Sukiennicki TLFowell DJ (2006 Nov 15). Distinct molecular program imposed on CD4+ T cell targets by CD4+CD25+ regulatory T cells. Journal of immunology (Baltimore, Md. : 1950). Au-Yeung BBKatzman SDFowell DJ (2006 Apr 1). Cutting edge: Itk-dependent signals required for CD4+ T cells to exert, but not gain, Th2 effector function. Journal of immunology (Baltimore, Md. : 1950). Sojka DKHughson ASukiennicki TLFowell DJ (2005 Dec 1). Early kinetic window of target T cell susceptibility to CD25+ regulatory T cell activity. Journal of immunology (Baltimore, Md. : 1950). Morales-Tirado VJohannson SHanson EHowell AZhang JSiminovitch KAFowell DJ (2004 Jul 15). Cutting edge: selective requirement for the Wiskott-Aldrich syndrome protein in cytokine, but not chemokine, secretion by CD4+ T cells. Journal of immunology (Baltimore, Md. : 1950). Gurunathan SStobie LPrussin CSacks DLGlaichenhaus NIwasaki AFowell DJLocksley RMChang JTWu CYSeder RA (2000 Jul 15). Requirements for the maintenance of Th1 immunity in vivo following DNA vaccination: a potential immunoregulatory role for CD8+ T cells. Journal of immunology (Baltimore, Md. : 1950). Pippig SDPeña-Rossi CLong JGodfrey WRFowell DJReiner SLBirkeland MLLocksley RMBarclay ANKilleen N (1999 Dec 15). Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40). Journal of immunology (Baltimore, Md. : 1950). Heath VLHutchings PFowell DJCooke AMason DW (1999 Nov). Peptides derived from murine insulin are diabetogenic in both rats and mice, but the disease-inducing epitopes are different: evidence against a common environmental cross-reactivity in the pathogenicity of type 1 diabetes. Diabetes. Fowell DJShinkai KLiao XCBeebe AMCoffman RLLittman DRLocksley RM (1999 Oct). Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells. Immunity. Fowell DJLocksley RM (1999 Jun). Leishmania major infection of inbred mice: unmasking genetic determinants of infectious diseases. BioEssays : news and reviews in molecular, cellular and developmental biology. Pingel SLaunois PFowell DJTurck CWSouthwood SSette AGlaichenhaus NLouis JALocksley RM (1999 Apr 5). Altered ligands reveal limited plasticity in the T cell response to a pathogenic epitope. The Journal of experimental medicine. Locksley RMPingel SLacy DWakil AEBix MFowell DJ (1999 Mar). Susceptibility to infectious diseases: Leishmania as a paradigm. The Journal of infectious diseases. Wakil AEWang ZERyan JCFowell DJLocksley RM (1998 Nov 2). Interferon gamma derived from CD4(+) T cells is sufficient to mediate T helper cell type 1 development. The Journal of experimental medicine. Fowell DJBix MShinkai KLacy DLocksley RM (1998 Sep). Disease susceptibility and development of the cytokine repertoire in the murine Leishmania major model. European cytokine network. Reiner SLFowell DJMoskowitz NHSwier KBrown DRBrown CRTurck CWScott PAKilleen NLocksley RM (1998 Jan 15). Control of Leishmania major by a monoclonal alpha beta T cell repertoire. Journal of immunology (Baltimore, Md. : 1950). Locksley RMFowell DJShinkai KWakil AELacy DBix M (1998). Development of CD4+ effector T cells and susceptibility to infectious diseases. Advances in experimental medicine and biology. Hagenbaugh ASharma SDubinett SMWei SHAranda RCheroutre HFowell DJBinder STsao BLocksley RMMoore KWKronenberg M (1997 Jun 16). Altered immune responses in interleukin 10 transgenic mice. The Journal of experimental medicine. Fowell DJMagram JTurck CWKilleen NLocksley RM (1997 May). Impaired Th2 subset development in the absence of CD4. Immunity. Saoudi ASeddon BFowell DMason D (1996 Dec 1). The thymus contains a high frequency of cells that prevent autoimmune diabetes on transfer into prediabetic recipients. The Journal of experimental medicine. Brown DRFowell DJCorry DBWynn TAMoskowitz NHCheever AWLocksley RMReiner SL (1996 Oct 1). Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses. The Journal of experimental medicine. Heath VLSaoudi ASeddon BPMoore NCFowell DJMason DW (1996 Apr). The role of the thymus in the control of autoimmunity. Journal of autoimmunity. Ramírez FFowell DJPuklavec MSimmonds SMason D (1996 Apr 1). Glucocorticoids promote a TH2 cytokine response by CD4+ T cells in vitro. Journal of immunology (Baltimore, Md. : 1950). Saoudi ASeddon BHeath VFowell DMason D (1996 Feb). The physiological role of regulatory T cells in the prevention of autoimmunity: the function of the thymus in the generation of the regulatory T cell subset. Immunological reviews. Fowell DJWakil AELocksley RM (1995 Sep). Interleukin-12 in murine leishmaniasis--match, flame or fuel? Research in immunology. Locksley RMWakil AECorry DBPingel SBix MFowell DJ (1995). The development of effector T cell subsets in murine Leishmania major infection. Ciba Foundation symposium. Fowell DPowrie FSaoudi ASeddon BHeath VMason D (1995). The role of subsets of CD4+ T cells in autoimmunity. Ciba Foundation symposium. Cyster JGFowell DBarclay AN (1994 Dec). Antigenic determinants encoded by alternatively spliced exons of CD45 are determined by the polypeptide but influenced by glycosylation. International immunology. Fowell DMason D (1993 Mar 1). Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential. The Journal of experimental medicine. Mason DFowell D (1992 Dec). T-cell subsets in autoimmunity. Current opinion in immunology. Fowell DMcKnight AJPowrie FDyke RMason D (1991 Oct). Subsets of CD4+ T cells and their roles in the induction and prevention of autoimmunity. Immunological reviews. Powrie FFowell DMcKnight AJMason D (1991 Jan). Lineage relationships and functions of CD4+ T-cell subsets in the rat. Research in immunology.