The protein-DNA assemblies that comprise chromatin serve to compact and store eukaryotic DNA in a systematic and orderly manner, and are involved in the regulation of nuclear processes such as transcription. Currently, research in the lab covers four areas related to chromatin structure and function.
Dr. Hayes is also the Principal Investigator of the William A. Bernhard Memorial Lab. Please visit the lab site to learn more about the physics & chemistry of DNA damage produced by ionizing radiation.
- Single-Molecule Studies of the Linker Histone H1 Binding to DNA and the Nucleosome.Biochemistry. 55, 2069-77. (2016 Apr 12).
- Base excision repair in chromatin: Insights from reconstituted systems.DNA Repair (Amst). 36, 77-85. (2015 Dec 01).
- A brief review of nucleosome structure.FEBS Lett. 589, 2914-22. (2015 Oct 07).