Welcome to the Jumping Frog Lab
The overall goal of our research is to understand the co-evolutionary relationships between the structure of selected molecules (e.g., non-classical MHC class Ib molecules) and their functions in innate and adaptive immunity against tumors and viruses using the frog Xenopus as animal model.
Current Research Projects
- Amphibian macrophage development and antiviral defenses.Dev Comp Immunol. 58, 60-7. (2016 May 01).
- Frog Virus 3 dissemination in the brain of tadpoles, but not in adult Xenopus, involves blood brain barrier dysfunction.Sci Rep. 6, 22508. (2016 Jan 01).
- Semi-solid tumor model in Xenopus laevis/gilli cloned tadpoles for intravital study of neovascularization, immune cells and melanophore infiltration.Dev Biol. 408, 205-12. (2015 Dec 15).