Optic Flow Evoked Potentials
We developed an approach to using radial optic flow stimuli to elicit visual motion evoked potentials. Subjects view a random pattern of stationary dots and after a few hundred milliseconds, the dots move to create a radial pattern of optic flow. We record the responses to optic flow onset and compare the N200 response amplitudes across subject groups.
We reasoned that optic flow response mechanisms identified in monkeys and humans might generate specific cortical evoked potentials. Further study revealed robust links between N200 amplitude, selective impairments of optic flow perception, and navigational impairment in AD patients. Current studies are underway to investigate the impact of behavioral and attentional demands on the optic flow evoked response.
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