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URMC / Labs / Cory-Slechta Lab / Projects / Enhanced Neurotoxicity of Metals in Combination With Other Pertinent Risk Factors

Enhanced Neurotoxicity of Metals in Combination With Other Pertinent Risk Factors

Photo of Experimental Project TaskThis project is focused on:

  • The potential synergistic neurodevelopmental consequences of developmental lead exposure in conjunction with maternal and/or offspring stress
  • Determination of whether enhanced toxicity of lead exposure and stress is seen with other neurotoxic metals, including methylmercury and arsenic, that likewise impact the HPA axis and brain mesocorticolimbic systems
  • The potential for positive vs negative early behavioral experience to modify the trajectory of consequences of developmental lead and/or prenatal stress exposures

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