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URMC / Labs / Kobie Lab / Projects / Advanced Immunoglobulin Repertoire Analysis

Advanced Immunoglobulin Repertoire Analysis

Advanced Immunoglobulin Repertoire Analysis Advanced Immunoglobulin Repertoire AnalysisThrough B cell receptor (BCR) sequencing at the single cell and global population level the exact specificity of the B cell response- its origin, potential, and fate can be determined. We have developed and optimized approaches for single cell and Next Generation Sequencing based Ig repertoire analysis coupled with recombinant monoclonal antibody generation to precisely resolve antigen-specific B cell responses in humans and various animal models.

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