URMC / Labs / Mosmann Lab / Publications Publications Pichichero MECasey JRAlmudevar ABasha SSurendran NKaur RMorris MLivingstone AMMosmann TR (2016 Jun 15). Functional Immune Cell Differences Associated With Low Vaccine Responses in Infants. The Journal of infectious diseases. Rebhahn JARoumanes DRQi YKhan AThakar JRosenberg ALee FEQuataert SASharma GMosmann TR (2016 Jan). Competitive SWIFT cluster templates enhance detection of aging changes. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Aghaeepour NChattopadhyay PChikina MDhaene TVan Gassen SKursa MLambrecht BNMalek MMcLachlan GJQian YQiu PSaeys YStanton RTong DVens CWalkowiak SWang KFinak GGottardo RMosmann TNolan GPScheuermann RHBrinkman RR (2016 Jan). A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Brinkman RRAghaeepour NFinak GGottardo RMosmann TScheuermann RH (2016 Jan). Automated analysis of flow cytometry data comes of age. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Finak GLangweiler MJaimes MMalek MTaghiyar JKorin YRaddassi KDevine LObermoser GPekalski MLPontikos NDiaz AHeck SVillanova FTerrazzini NKern FQian YStanton RWang KBrandes ARamey JAghaeepour NMosmann TScheuermann RHReed EPalucka KPascual VBlomberg BBNestle FNussenblatt RBBrinkman RRGottardo RMaecker HMcCoy JP (2016). Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium. Scientific reports. Deng NMosmann TR (2015 Aug). Optimization of the cytokine secretion assay for human IL-2 in single and combination assays. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Brinkman RRAghaeepour NFinak GGottardo RMosmann TScheuermann RH (2015 Jul). State-of-the-Art in the Computational Analysis of Cytometry Data. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Kvistborg PGouttefangeas CAghaeepour NCazaly AChattopadhyay PKChan CEckl JFinak GHadrup SRMaecker HTMaurer DMosmann TQiu PScheuermann RHWelters MJFerrari GBrinkman RRBritten CM (2015 Apr 21). Thinking outside the gate: single-cell assessments in multiple dimensions. Immunity. Bobo BPhelan DRebhahn JPiepenbrink MSZheng BMosmann TRKobie JJDeLouise LA (2014 Sep 21). Microbubble array diffusion assay for the detection of cell secreted factors. Lab on a chip. Rebhahn JADeng NSharma GLivingstone AMHuang SMosmann TR (2014 Aug). An animated landscape representation of CD4+ T-cell differentiation, variability, and plasticity: insights into the behavior of populations versus cells. European journal of immunology. Mosmann TRNaim IRebhahn JDatta SCavenaugh JSWeaver JMSharma G (2014 May). SWIFT-scalable clustering for automated identification of rare cell populations in large, high-dimensional flow cytometry datasets, part 2: biological evaluation. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Naim IDatta SRebhahn JCavenaugh JSMosmann TRSharma G (2014 May). SWIFT-scalable clustering for automated identification of rare cell populations in large, high-dimensional flow cytometry datasets, part 1: algorithm design. Cytometry. Part A : the journal of the International Society for Analytical Cytology. Miao HSangster MYLivingstone AMHilchey SPZhang LTopham DJMosmann TRHolden-Wiltse JPerelson ASWu HZand MS (2014). Modeling the dynamics and migratory pathways of virus-specific antibody-secreting cell populations in primary influenza infection. PloS one. Deng NWeaver JMMosmann TR (2014). Cytokine diversity in the Th1-dominated human anti-influenza response caused by variable cytokine expression by Th1 cells, and a minor population of uncommitted IL-2+IFNγ- Thpp cells. PloS one. Sharma SKRoumanes DAlmudevar AMosmann TRPichichero ME (2013 Jun 26). CD4+ T-cell responses among adults and young children in response to Streptococcus pneumoniae and Haemophilus influenzae vaccine candidate protein antigens. Vaccine. Aghaeepour NFinak G Hoos HMosmann TRBrinkman RGottardo RScheuermann RH (2013 Mar). Critical assessment of automated flow cytometry data analysis techniques. Nature methods. Weaver JMYang HRoumanes DLee FEWu HTreanor JJMosmann TR (2013). Increase in IFNγ(-)IL-2(+) cells in recent human CD4 T cell responses to 2009 pandemic H1N1 influenza. PloS one. Moore KWVieira PFiorentino DFTrounstine MLKhan TAMosmann TR (2012 Sep 1). Pillars article: homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. Science. 1990. 248: 1230-1234. Journal of immunology (Baltimore, Md. : 1950). Li XMiao HHenn ATopham DJWu HZand MSMosmann TR (2012 Jun 29). Ki-67 expression reveals strong, transient influenza specific CD4 T cell responses after adult vaccination. Vaccine. Qi YOperario DJGeoras SNMosmann TR (2012). The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin. PloS one. Wu HKumar AMiao HHolden-Wiltse JMosmann TRLivingstone AMBelz GTPerelson ASZand MSTopham DJ (2011 Nov 1). Modeling of influenza-specific CD8+ T cells during the primary response indicates that the spleen is a major source of effectors. Journal of immunology (Baltimore, Md. : 1950). Mace CRTopham DJMosmann TRQuataert SATreanor JJMiller BL (2011 Jan 15). Label-free, arrayed sensing of immune response to influenza antigens. Talanta. Qi YOperario DJOberholzer CMKobie JJLooney RJGeoras SNMosmann TR (2010 Dec). Human basophils express amphiregulin in response to T cell-derived IL-3. The Journal of allergy and clinical immunology. Miao HHollenbaugh JAZand MSHolden-Wiltse JMosmann TRPerelson ASWu HTopham DJ (2010 Jul). Quantifying the early immune response and adaptive immune response kinetics in mice infected with influenza A virus. Journal of virology. Qian YWei CEun-Hyung Lee FCampbell JHalliley JLee JACai JKong YMSadat EThomson EDunn PSeegmiller ACKarandikar NJTipton CMMosmann TSanz IScheuermann RH (2010). Elucidation of seventeen human peripheral blood B-cell subsets and quantification of the tetanus response using a density-based method for the automated identification of cell populations in multidimensional flow cytometry data. Cytometry. Part B, Clinical cytometry. Naim IDatta SSharma GCavenaugh JMosmann TR (2010 Jan 01). SWIFT: Scalable weighted iterative sampling for flow cytometry clustering. Proc. IEEE Intl. Conf. Acoustics Speech and Sig. Proc.. Mosmann TRKobie JJLee FEQuataert SA (2009 Dec). T helper cytokine patterns: defined subsets, random expression, and external modulation. Immunologic research. Hilchey SPKobie JJCochran MRSecor-Socha SWang JCHyrien OBurack WRMosmann TRQuataert SABernstein SH (2009 Nov 15). Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine-mediated T cell hyporesponsiveness. Journal of immunology (Baltimore, Md. : 1950). Lee HYHawkins EZand MSMosmann TWu HHodgkin PDPerelson AS (2009 Oct). Interpreting CFSE obtained division histories of B cells in vitro with Smith-Martin and cyton type models. Bulletin of mathematical biology. Henn ADRebhahn JBrown MAMurphy AJCoca MNHyrien OPellegrin TMosmann TZand MS (2009 Sep 1). Modulation of single-cell IgG secretion frequency and rates in human memory B cells by CpG DNA, CD40L, IL-21, and cell division. Journal of immunology (Baltimore, Md. : 1950). Friedberg JWKelly JLNeuberg DPeterson DRKutok JLSalloum RBrenn TFisher DCRonan EDalton VRich LMarquis DSims PRothberg PGLiesveld JFisher RICoffman RMosmann TFreedman AS (2009 Aug). Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma. British journal of haematology. Lee HYTopham DJPark SYHollenbaugh JTreanor JMosmann TRJin XWard BMMiao HHolden-Wiltse JPerelson ASZand MWu H (2009 Jul). Simulation and prediction of the adaptive immune response to influenza A virus infection. Journal of virology. Hilchey SPHyrien OMosmann TRLivingstone AMFriedberg JWYoung FFisher RIKelleher RJBankert RBBernstein SH (2009 Apr 16). Rituximab immunotherapy results in the induction of a lymphoma idiotype-specific T-cell response in patients with follicular lymphoma: support for a "vaccinal effect" of rituximab. Blood. Seavey MMMosmann TR (2009 Apr 14). Estradiol-induced vaginal mucus inhibits antigen penetration and CD8(+) T cell priming in response to intravaginal immunization. Vaccine. Wang JCKobie JJZhang LCochran MMosmann TRRitchlin CTQuataert SA (2009 Feb 28). An 11-color flow cytometric assay for identifying, phenotyping, and assessing endocytic ability of peripheral blood dendritic cell subsets in a single platform. Journal of immunological methods. Rebhahn JABishop CDivekar AAJiminez-Garcia KKobie JJLee FEMaupin GMSnyder-Cappione JEZaiss DMMosmann TR (2008 Oct). Automated analysis of two- and three-color fluorescent Elispot (Fluorospot) assays for cytokine secretion. Computer methods and programs in biomedicine. Zaiss DMSijts AJMosmann TR (2008 Oct). Enumeration of cytotoxic CD8 T cells ex vivo during the response to Listeria monocytogenes infection. Infection and immunity. Seavey MMMosmann TR (2008). Immunoregulation of fetal and anti-paternal immune responses. Immunologic research. Lee FEWalsh EEFalsey ARLumb MEOkam NVLiu NDivekar AAHall CBMosmann TR (2007 Jun 15). Human infant respiratory syncytial virus (RSV)-specific type 1 and 2 cytokine responses ex vivo during primary RSV infection. The Journal of infectious diseases. Richter MRay SJChapman TJAustin SJRebhahn JMosmann TRGardner HKotelianski VdeFougerolles ARTopham DJ (2007 Apr 1). Collagen distribution and expression of collagen-binding alpha1beta1 (VLA-1) and alpha2beta1 (VLA-2) integrins on CD4 and CD8 T cells during influenza infection. Journal of immunology (Baltimore, Md. : 1950). Zaiss DMYang LShah PRKobie JJUrban JFMosmann TR (2006 Dec 15). Amphiregulin, a TH2 cytokine enhancing resistance to nematodes. Science (New York, N.Y.). Seavey MMMosmann TR (2006 Dec 1). Paternal antigen-bearing cells transferred during insemination do not stimulate anti-paternal CD8+ T cells: role of estradiol in locally inhibiting CD8+ T cell responses. Journal of immunology (Baltimore, Md. : 1950). Kobie JJShah PRYang LRebhahn JAFowell DJMosmann TR (2006 Nov 15). T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine. Journal of immunology (Baltimore, Md. : 1950). Snyder-Cappione JEDivekar AAMaupin GMJin XDemeter LMMosmann TR (2006 Feb 15). HIV-specific cytotoxic cell frequencies measured directly ex vivo by the Lysispot assay can be higher or lower than the frequencies of IFN-gamma-secreting cells: anti-HIV cytotoxicity is not generally impaired relative to other chronic virus responses. Journal of immunology (Baltimore, Md. : 1950). Divekar AAZaiss DMLee FELiu DTopham DJSijts AJMosmann TR (2006 Feb 1). Protein vaccines induce uncommitted IL-2-secreting human and mouse CD4 T cells, whereas infections induce more IFN-gamma-secreting cells. Journal of immunology (Baltimore, Md. : 1950). Yang LKobie JJMosmann TR (2005 Nov 15). CD73 and Ly-6A/E distinguish in vivo primed but uncommitted mouse CD4 T cells from type 1 or type 2 effector cells. Journal of immunology (Baltimore, Md. : 1950). Lee FEWalsh EEFalsey ARLiu NLiu DDivekar ASnyder-Cappione JEMosmann TR (2005 Nov). The balance between influenza- and RSV-specific CD4 T cells secreting IL-10 or IFNgamma in young and healthy-elderly subjects. Mechanisms of ageing and development. Mosmann TRCherwinski HBond MWGiedlin MACoffman RL (2005 Jul 1). Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. 1986. Journal of immunology (Baltimore, Md. : 1950). Ma JMosmann TWu H (2005). Design considerations for a web-based database system of ELISpot assay in immunological research. AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. Mosmann TRLivingstone AM (2004 Jun). Dendritic cells: the immune information management experts. Nature immunology.