URMC / Labs / O'Connell Lab / Lab Members

Lab Members

Principal Investigator

Research Interest: Biochemical mechanisms of RNA-mediated gene regulation; RNA-targeting CRISPR tool development

Bogdan Polevoda, Ph.D.
Research Assistant Professor
MC
Phone: (585) 276-4107
Email Bogdan

Research Interest: The two cotranslational processes, cleavage of N-terminal methionine and N-terminal acetylation (N- acetylation).

Ning Tong, B.M., Ph.D.
Research Assistant Professor
MC
Phone: (585) 276-4107
Email Ning

Research Interest:

Picking up the Pieces: The Fragmented Process of Cas13 Mediated RNA Cleavage in Human Cells

Research Interest:

Structural Studies of Cas13b Accessory Protein Csx27

Research Interest:

Pulling the plug on bacteriophage infection: investigating the molecular mechanism of activation of CRISPR-Csx28

Research Interest: RNA biology, CRISPR-Cas systems. Understanding gRNA design rules for efficient and specific Cas13 RNA-binding in human cells.

Research Interest:

The role of the Type VI CRISPR-Cas accessory protein Csx27 in CRISPR-Cas13 mediated anti-viral immunity

Research Interest:

Nucleic Acid Biology, Epigenetics, and Development. My project is focused on the role of H2A.Z in epigenetic inheritance.