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URMC / Labs / Ovitt Lab / Research Projects / Homeostasis and Regeneration
 

Homeostasis and Regeneration

We are working to identify cells involved in maintenance and regeneration of head and neck exocrine glands. We recently demonstrated that salivary gland homeostasis is based predominantly on self-duplication of differentiated secretory acinar cells. However, the mechanisms – and cell types- involved in gland regeneration remain unresolved.

Current projects include: investigations into the normal mechanisms of exocrine gland development and maintenance; and investigating regeneration in salivary, lacrimal and olfactory glands.

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