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Paine Lab

Molecular Mechanisms of Inflammatory Bone Diseases

Psoriatic arthritis (PsA) is a prevalent musculoskeletal disorder which develops in up to 30% of patients with psoriasis and is associated with several co-morbidities that increase the risk of cardiovascular disease. Currently there is no diagnostic test for PsA and no identified biomarkers to predict the risk of developing arthritis once psoriasis is present. Defining such markers would be instrumental in earlier and more accurate diagnosis and treatment.

Ananta Paine, Ph.D.

Ananta Paine, Ph.D.
Principal Investigator

Research Projects
Lab Members
Publications
SOPs

Projects

Bench to Bedside Research

Bench to Bedside Research Using Systems Biology Research

Publications

    1. Paine A
    2. Dorresteijn MJ
    3. Zilian E
    4. Maaike GE
    5. Blasczyk R
    6. Wagener F
    7. Pickkers P
    8. Immenschuh S
    Lipopolysaccharide-Dependent Down-Regulation of Heme Oxygenase-1 via a Bach1-Regulated Pathway in Human Mononuclear; Free Radic Biol Med; Vol S0891-5849(14), pp. 1080-6. 2014 Jan 01.
    1. Saragih H
    2. Zilian E
    3. Jaimes Y'
    4. Paine A
    5. Figueiredo C
    6. Eiz-Vesper B
    7. Blasczyk R
    8. Larmann J
    9. Theilmeier G
    10. Andrei-Selmer C
    11. Becker J
    12. Santoso S
    13. Immenschuh S
    PECAM-1 Regulates Endothelial Heme Oxygenase-1 Expression via a Redox-dependent Nrf2-Mediated; Thrombosis and Haemostasis; Vol 111(6). 2014 Jan 01.
    1. Jagodic M
    2. Stridh P
    3. Gad AK
    4. Paine A
    5. Udekwu KI
    6. Sjöholm LK
    7. Svensson M
    8. Pan-Hammarström Q
    Nurture your scientific curiosity early in your research; Nat Genet; Vol 45(2), pp. 116-8. 2013 Jan 01.

View All Publications

Affiliations

 

In the News

March 29, 2021
Drs. Rangel-Moreno and Garcia-Hernandez Present at the Research Seminars in Biological Sciences

March 15, 2021
Dr. Jennifer Anolik Presents at the Canadian Arthritis Research Conference

February 23, 2021
Dr. Javier Rangel-Moreno Discusses COVID-19 Vaccines

December 4, 2020
AIR Research Presented at National Meeting

September 16, 2020
Drs. Anthony Ocon and Christopher Ritchlin Among Authors of a Publication Outlining Guidance for Management of Psoriatic Disease During the Pandemic

All News »

Contact Us

 Paine Lab
601 Elmwood Ave/Box 695
Rochester, NY 14642

 (585) 275-2891