URMC / Labs / Schwarz Lab / Publications Publications Trombetta RInzana JASchwarz EMKates SLAwad HA (2016 Jun 20). 3D Printing of Calcium Phosphate Ceramics for Bone Tissue Engineering and Drug Delivery. Annals of biomedical engineering. Chen YHallab NJLiao YSNarayan VSchwarz EMXie C (2016 May). Antioxidant impregnated ultra-high molecular weight polyethylene wear debris particles display increased bone remodeling and a superior osteogenic:osteolytic profile vs. conventional UHMWPE particles in a murine calvaria model. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Kuzin IIKates SLJu YZhang LRahimi HWojciechowski WBernstein SHBurack RSchwarz EMBottaro A (2016 Apr 23). Increased numbers of CD23(+) CD21(hi) Bin-like B cells in human reactive and rheumatoid arthritis lymph nodes. European journal of immunology. Inzana JASchwarz EMKates SLAwad HA (2016 Mar). Biomaterials approaches to treating implant-associated osteomyelitis. Biomaterials. Antebi BZhang LSheyn DPelled GZhang XGazit ZSchwarz EMGazit D (2016 Mar). Controlling Arteriogenesis and Mast Cells Are Central to Bioengineering Solutions for Critical Bone Defect Repair Using Allografts. Bioengineering. Sheyn DShapiro GTawackoli WJun DSKoh YKang KBSu SDa XBen-David SBez MYalon EAntebi BAvalos PStern TZelzer ESchwarz EMGazit ZPelled GBae HMGazit D (2016 Feb). PTH Induces Systemically Administered Mesenchymal Stem Cells to Migrate to and Regenerate Spine Injuries. Molecular therapy : the journal of the American Society of Gene Therapy. Zhang LChang MBeck CASchwarz EMBoyce BF (2016). Analysis of new bone, cartilage, and fibrosis tissue in healing murine allografts using whole slide imaging and a new automated histomorphometric algorithm. Bone research. Rahimi HBell RBouta EMWood RWXing LRitchlin CTSchwarz EM (2016). Lymphatic imaging to assess rheumatoid flare: mechanistic insights and biomarker potential. Arthritis research & therapy. Nishitani KSutipornpalangkul Wde Mesy Bentley KLVarrone JJBello-Irizarry SNIto HMatsuda SKates SLDaiss JLSchwarz EM (2015 Sep). Quantifying the natural history of biofilm formation in vivo during the establishment of chronic implant-associated Staphylococcus aureus osteomyelitis in mice to identify critical pathogen and host factors. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Nishitani KBeck CARosenberg AFKates SLSchwarz EMDaiss JL (2015 Sep). A Diagnostic Serum Antibody Test for Patients With Staphylococcus aureus Osteomyelitis. Clinical orthopaedics and related research. Xie CLi YLi QChen YYao JYin GBi QO'Keefe RJSchwarz EMTyler W (2015 Sep). Increased Insulin mRNA Binding Protein-3 Expression Correlates with Vascular Enhancement of Renal Cell Carcinoma by Intravenous Contrast-CT and is Associated with Bone Metastasis. Journal of bone oncology. Kuzin IIBouta EMSchwarz EMBottaro A (2015 Aug). TNF signals are dispensable for the generation of CD23+ CD21/35-high CD1d-high B cells in inflamed lymph nodes. Cellular immunology. Farnsworth CWShehatou CTMaynard RNishitani KKates SLZuscik MJSchwarz EMDaiss JLMooney RA (2015 Jun). A humoral immune defect distinguishes the response to Staphylococcus aureus infections in mice with obesity and type 2 diabetes from that in mice with type 1 diabetes. Infection and immunity. Liang QJu YChen YWang WLi JZhang LXu HWood RWSchwarz EMBoyce BFWang YXing L (2016). Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice. Arthritis research & therapy. Zhang MFeigenson MSheu TJAwad HASchwarz EMJonason JHLoiselle AEO'Keefe RJ (2015 Mar). Loss of the PGE2 receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength. Bone. Inzana JASchwarz EMKates SLAwad HA (2015 Mar). A novel murine model of established Staphylococcal bone infection in the presence of a fracture fixation plate to study therapies utilizing antibiotic-laden spacers after revision surgery. Bone. Farhat YMAl-Maliki AAEasa AO'Keefe RJSchwarz EMAwad HA (2015 Feb). TGF-β1 Suppresses Plasmin and MMP Activity in Flexor Tendon Cells via PAI-1: Implications for Scarless Flexor Tendon Repair. Journal of cellular physiology. Bouta EMLi JJu YBrown EBRitchlin CTXing LSchwarz EM (2015 Jan 15). The Role of the Lymphatic System in Inflammatory-Erosive Arthritis. Seminars in cell & developmental biology. Inzana JATrombetta RPSchwarz EMKates SLAwad HA (2015). 3D printed bioceramics for dual antibiotic delivery to treat implant-associated bone infection. European cells & materials. Bouta EMBanik PDWood RWRahimi HRitchlin CTThiele RGSchwarz EM (2014 Oct 31). Validation of Power Doppler Versus Contrast Enhanced Magnetic Resonance Imaging Quantification of Joint Inflammation in Murine Inflammatory Arthritis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Varrone JJde Mesy Bentley KLBello-Irizarry SNNishitani KMack SHunter JGKates SLDaiss JLSchwarz EM (2014 Oct). Passive immunization with anti-glucosaminidase monoclonal antibodies protects mice from implant-associated osteomyelitis by mediating opsonophagocytosis of Staphylococcus aureus megaclusters. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Papuga MOBeck CAKates SLSchwarz EMMaloney MD (2014 Jun). Validation of GAITRite and PROMIS as high-throughput physical function outcome measures following ACL reconstruction. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Yukata KXie CLi TFTakahata MHoak DKondabolu SZhang XAwad HASchwarz EMBeck CAJonason JHO'Keefe RJ (2014 May). Aging periosteal progenitor cells have reduced regenerative responsiveness to bone injury and to the anabolic actions of PTH 1-34 treatment. Bone. Inzana JAOlvera DFuller SMKelly JPGraeve OASchwarz EMKates SLAwad HA (2014 Apr). 3D printing of composite calcium phosphate and collagen scaffolds for bone regeneration. Biomaterials. Bouta EMWood RWBrown EBRahimi HRitchlin CTSchwarz EM (2014 Mar 15). In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice. The Journal of physiology. Long TZhu ZAwad HASchwarz EMHilton MJDong Y (2014 Mar). The effect of mesenchymal stem cell sheets on structural allograft healing of critical sized femoral defects in mice. Biomaterials. Nishitani KSchwarz EM (2014 Mar). Regenerative medicine: Cartilage transplants hold promise for challenging bone defects. Nature reviews. Rheumatology. Dhillon RSZhang LSchwarz EMBoyce BFXie C (2014). The murine femoral bone graft model and a semiautomated histomorphometric analysis tool. Methods in molecular biology (Clifton, N.J.). Hasslund SDadali TUlrich-Vinther MSøballe KSchwarz EMAwad HA (2014). Freeze-dried allograft-mediated gene or protein delivery of growth and differentiation factor 5 reduces reconstructed murine flexor tendon adhesions. Journal of tissue engineering. Schwarz EMKates SLAlt V (2014 Jan). The 1st International Consensus Meeting on Periprosthetic Joint Infection. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Rosenberg AFan HChiu YGBolce RTabechian DBarrett RMoorehead SBaribaud FLiu HPeffer NShealy DSchwarz EMRitchlin CT (2014). Divergent gene activation in peripheral blood and tissues of patients with rheumatoid arthritis, psoriatic arthritis and psoriasis following infliximab therapy. PloS one. Gao LSheu TJDong YHoak DMZuscik MJSchwarz EMHilton MJO'Keefe RJJonason JH (2013 Dec 15). TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages. Journal of cell science. Gedbjerg NLaRosa RHunter JGVarrone JJKates SLSchwarz EMDaiss JL (2013 Nov 20). Anti-glucosaminidase IgG in sera as a biomarker of host immunity against Staphylococcus aureus in orthopaedic surgery patients. The Journal of bone and joint surgery. American volume. Ju YLi JXie CRitchlin CTXing LHilton MJSchwarz EM (2013 Sep). Troponin T3 expression in skeletal and smooth muscle is required for growth and postnatal survival: characterization of Tnnt3(tm2a(KOMP)Wtsi) mice. Genesis (New York, N.Y. : 2000). Green JMHallab NJLiao YSNarayan VSchwarz EMXie C (2013 May). Anti-oxidation treatment of ultra high molecular weight polyethylene components to decrease periprosthetic osteolysis: evaluation of osteolytic and osteogenic properties of wear debris particles in a murine calvaria model. Current rheumatology reports. Dhillon RSXie CTyler WCalvi LMAwad HAZuscik MJO'Keefe RJSchwarz EM (2013 Mar). PTH-enhanced structural allograft healing is associated with decreased angiopoietin-2-mediated arteriogenesis, mast cell accumulation, and fibrosis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Rahimi HMaurer KSong LAkhter EPetri MSullivan KE (2013 Mar). Aberrant regulation of the integrin very late antigen-4 in systemic lupus erythematosus. Lupus. Inzana JAMaher JRTakahata MSchwarz EMBerger AJAwad HA (2013 Feb 22). Bone fragility beyond strength and mineral density: Raman spectroscopy predicts femoral fracture toughness in a murine model of rheumatoid arthritis. Journal of biomechanics. Li JJu YBouta EMXing LWood RWKuzin IBottaro ARitchlin CTSchwarz EM (2013 Jan). Efficacy of B cell depletion therapy for murine joint arthritis flare is associated with increased lymphatic flow. Arthritis and rheumatism. Bouta EMJu YRahimi Hde Mesy-Bentley KLWood RWXing LSchwarz EM (2013). Power Doppler ultrasound phenotyping of expanding versus collapsed popliteal lymph nodes in murine inflammatory arthritis. PloS one. Juneja SCSchwarz EMO'Keefe RJAwad HA (2013). Cellular and molecular factors in flexor tendon repair and adhesions: a histological and gene expression analysis. Connective tissue research. Liu HSchwarz EMXie C (2013). Dual differentiation-exogenous mesenchymal stem cell therapy for traumatic spinal cord injury repair in a murine hemisection model. Stem cells international. Takahata MMaher JRJuneja SCInzana JXing LSchwarz EMBerger AJAwad HA (2012 Nov). Mechanisms of bone fragility in a mouse model of glucocorticoid-treated rheumatoid arthritis: implications for insufficiency fracture risk. Arthritis and rheumatism. Santoni BGEhrhart NBetancourt-Benitez RBeck CASchwarz EM (2012 Sep). Quantifying massive allograft healing of the canine femur in vivo and ex vivo: a pilot study. Clinical orthopaedics and related research. Wang MTang DShu BWang BJin HHao SDresser KAShen JIm HJSampson ERRubery PTZuscik MJSchwarz EMO'Keefe RJWang YChen D (2012 Aug). Conditional activation of β-catenin signaling in mice leads to severe defects in intervertebral disc tissue. Arthritis and rheumatism. Rahimi HRitchlin CT (2012 Aug). Altered bone biology in psoriatic arthritis. Current rheumatology reports. Moshkani SKuzin IIAdewale FJansson JSanz ISchwarz EMBottaro A (2012 Jun 15). CD23+ CD21(high) CD1d(high) B cells in inflamed lymph nodes are a locally differentiated population with increased antigen capture and activation potential. Journal of immunology (Baltimore, Md. : 1950). Ju YRahimi HLi JWood RWXing LSchwarz EM (2012 Jun). Validation of 3-dimensional ultrasound versus magnetic resonance imaging quantification of popliteal lymph node volume as a biomarker of erosive inflammatory arthritis in mice. Arthritis and rheumatism. Takahata MAwad HAO'Keefe RJBukata SVSchwarz EM (2012 Mar). Endogenous tissue engineering: PTH therapy for skeletal repair. Cell and tissue research. Xie CSchwarz EMSampson ERDhillon RSLi DO'Keefe RJTyler W (2012 Feb). Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Takahata MSchwarz EMChen TO'Keefe RJAwad HA (2012 Jan). Delayed short-course treatment with teriparatide (PTH(1-34)) improves femoral allograft healing by enhancing intramembranous bone formation at the graft-host junction. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Loiselle AEFrisch BJWolenski MJacobson JACalvi LMSchwarz EMAwad HAO'Keefe RJ (2012). Bone marrow-derived matrix metalloproteinase-9 is associated with fibrous adhesion formation after murine flexor tendon injury. PloS one. Farhat YMAl-Maliki AAChen TJuneja SCSchwarz EMO'Keefe RJAwad HA (2012). Gene expression analysis of the pleiotropic effects of TGF-β1 in an in vitro model of flexor tendon healing. PloS one. Chiu YHMensah KASchwarz EMJu YTakahata MFeng CMcMahon LAHicks DGPanepento BKeng PCRitchlin CT (2012 Jan). Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC-STAMP). Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Dhillon RSSchwarz EMMaloney MD (2012). Platelet-rich plasma therapy - future or trend? Arthritis research & therapy. Bouta EMWood RWPerry SWBrown EBRitchlin CTXing LSchwarz EM (2011 Dec). Measuring intranodal pressure and lymph viscosity to elucidate mechanisms of arthritic flare and therapeutic outcomes. Annals of the New York Academy of Sciences. Myakishev-Rempel MKuper JMintz BHutchinson SVoris JZavislan KOffley SNardia FBYaseen ZYen TZavislan JMMaloney MDSchwarz EM (2011 Nov). Investigation of the peak action wavelength of light-activated gene transduction. Gene therapy. Sampson ERHilton MJTian YChen DSchwarz EMMooney RABukata SVO'Keefe RJAwad HPuzas JERosier RNZuscik MJ (2011 Sep 21). Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis. Science translational medicine. Papuga MOKwok EYou ZRubery PTDougherty PEPryhuber GBeck CAHilton MJAwad HASchwarz EM (2011 Sep). TNF is required for the induction but not the maintenance of compression-induced BME signals in murine tail vertebrae: limitations of anti-TNF therapy for degenerative disc disease. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Yazici CTakahata MReynolds DGXie CSamulski RJSamulski JBeecham EJGertzman AASpilker MZhang XO'Keefe RJAwad HASchwarz EM (2011 Aug). Self-complementary AAV2.5-BMP2-coated femoral allografts mediated superior bone healing versus live autografts in mice with equivalent biomechanics to unfractured femur. Molecular therapy : the journal of the American Society of Gene Therapy. Sampson ERBeck CAKetz JCanary KLHilton MJAwad HSchwarz EMChen DO'Keefe RJRosier RNZuscik MJ (2011 Aug). Establishment of an index with increased sensitivity for assessing murine arthritis. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Sampson ERMartin BAMorris AEXie CSchwarz EMO'Keefe RJRosier RN (2011 Jun). The orally bioavailable met inhibitor PF-2341066 inhibits osteosarcoma growth and osteolysis/matrix production in a xenograft model. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Dhillon RSSchwarz EM (2011 Jun 1). Teriparatide Therapy as an Adjuvant for Tissue Engineering and Integration of Biomaterials. Journal of materials research. Zhang MHo HCSheu TJBreyer MDFlick LMJonason JHAwad HASchwarz EMO'Keefe RJ (2011 Apr). EP1(-/-) mice have enhanced osteoblast differentiation and accelerated fracture repair. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Sampson ERAmin VSchwarz EMO'Keefe RJRosier RN (2011 Apr). The histone deacetylase inhibitor vorinostat selectively sensitizes fibrosarcoma cells to chemotherapy. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Varrone JJLi DDaiss JLSchwarz EM (2011 Apr 1). Anti-Glucosaminidase Monoclonal Antibodies as a Passive Immunization for Methicillin-Resistant Staphylococcus aureus (MRSA) Orthopaedic Infections. BoneKEy osteovision. Reynolds DGTakahata MLerner ALO'Keefe RJSchwarz EMAwad HA (2011 Mar 1). Teriparatide therapy enhances devitalized femoral allograft osseointegration and biomechanics in a murine model. Bone. Jacobson JAYanoso-Scholl LReynolds DGDadali TBradica GBukata SPuzas EJZuscik MJRosier RO'Keefe RJSchwarz EMAwad HA (2011 Feb). Teriparatide therapy and beta-tricalcium phosphate enhance scaffold reconstruction of mouse femoral defects. Tissue engineering. Part A. Li JZhou QWood RWKuzin IBottaro ARitchlin CTXing LSchwarz EM (2011). CD23(+)/CD21(hi) B-cell translocation and ipsilateral lymph node collapse is associated with asymmetric arthritic flare in TNF-Tg mice. Arthritis research & therapy. Yanoso-Scholl LJacobson JABradica GLerner ALO'Keefe RJSchwarz EMZuscik MJAwad HA (2010 Dec 1). Evaluation of dense polylactic acid/beta-tricalcium phosphate scaffolds for bone tissue engineering. Journal of biomedical materials research. Part A. Papuga MOProulx STKwok EYou ZRubery PTDougherty PEHilton MJAwad HASchwarz EM (2010 Sep). Chronic axial compression of the mouse tail segment induces MRI bone marrow edema changes that correlate with increased marrow vasculature and cellularity. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Gunnell LMJonason JHLoiselle AEKohn ASchwarz EMHilton MJO'Keefe RJ (2010 Aug). TAK1 regulates cartilage and joint development via the MAPK and BMP signaling pathways. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Li TFGao LSheu TJSampson ERFlick LMKonttinen YTChen DSchwarz EMZuscik MJJonason JHO'Keefe RJ (2010 Aug). Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor beta-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis. Arthritis and rheumatism. Li JKuzin IMoshkani SProulx STXing LSkrombolas DDunn RSanz ISchwarz EMBottaro A (2010 Jun 1). Expanded CD23(+)/CD21(hi) B cells in inflamed lymph nodes are associated with the onset of inflammatory-erosive arthritis in TNF-transgenic mice and are targets of anti-CD20 therapy. Journal of immunology (Baltimore, Md. : 1950). Mensah KARitchlin CTSchwarz EM (2010 Apr). RANKL induces heterogeneous DC-STAMP(lo) and DC-STAMP(hi) osteoclast precursors of which the DC-STAMP(lo) precursors are the master fusogens. Journal of cellular physiology. Mensah KAMathian AMa LXing LRitchlin CTSchwarz EM (2010 Apr). Mediation of nonerosive arthritis in a mouse model of lupus by interferon-alpha-stimulated monocyte differentiation that is nonpermissive of osteoclastogenesis. Arthritis and rheumatism. Li DGromov KProulx STXie CLi JCrane DPSøballe KO'Keefe RJAwad HAXing LSchwarz EM (2010 Mar). Effects of antiresorptive agents on osteomyelitis: novel insights into the pathogenesis of osteonecrosis of the jaw. Annals of the New York Academy of Sciences. Schwarz EMProulx STRitchlin CTBoyce BFXing L (2010). The role of bone marrow edema and lymphangiogenesis in inflammatory-erosive arthritis. Advances in experimental medicine and biology. Chiu YGShao TFeng CMensah KAThullen MSchwarz EMRitchlin CT (2010). CD16 (FcRgammaIII) as a potential marker of osteoclast precursors in psoriatic arthritis. Arthritis research & therapy. Mensah KALi JSchwarz EM (2009 Dec). The emerging field of osteoimmunology. Immunologic research. Tsutsumi RXie CWei XZhang MZhang XFlick LMSchwarz EMO'Keefe RJ (2009 Oct). PGE2 signaling through the EP4 receptor on fibroblasts upregulates RANKL and stimulates osteolysis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Darowish MRahman RLi PBukata SVGelinas JHuang WFlick LMSchwarz EMO'Keefe RJ (2009 Oct). Reduction of particle-induced osteolysis by interleukin-6 involves anti-inflammatory effect and inhibition of early osteoclast precursor differentiation. Bone. Guo RZhou QProulx STWood RJi RCRitchlin CTPytowski BZhu ZWang YJSchwarz EMXing L (2009 Sep). Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis. Arthritis and rheumatism. Crane DPGromov KLi DSøballe KWahnes CBüchner HHilton MJO'Keefe RJMurray CKSchwarz EM (2009 Aug). Efficacy of colistin-impregnated beads to prevent multidrug-resistant A. baumannii implant-associated osteomyelitis. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Xie CLiang BXue MLin ASLoiselle ASchwarz EMGuldberg REO'Keefe RJZhang X (2009 Aug). Rescue of impaired fracture healing in COX-2-/- mice via activation of prostaglandin E2 receptor subtype 4. The American journal of pathology. Loiselle AEBragdon GAJacobson JAHasslund SCortes ZESchwarz EMMitten DJAwad HAO'Keefe RJ (2009 Jun). Remodeling of murine intrasynovial tendon adhesions following injury: MMP and neotendon gene expression. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Reynolds DGShaikh SPapuga MOLerner ALO'Keefe RJSchwarz EMAwad HA (2009 May). muCT-based measurement of cortical bone graft-to-host union. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Naik AAXie CZuscik MJKingsley PSchwarz EMAwad HGuldberg RDrissi HPuzas JEBoyce BZhang XO'Keefe RJ (2009 Feb). Reduced COX-2 expression in aged mice is associated with impaired fracture healing. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Xie CMing XWang QSchwarz EMGuldberg REO'Keefe RJZhang X (2008 Dec). COX-2 from the injury milieu is critical for the initiation of periosteal progenitor cell mediated bone healing. Bone. Tsutsumi RHock CBechtold CDProulx STBukata SVIto HAwad HANakamura TO'Keefe RJSchwarz EM (2008 Oct). Differential effects of biologic versus bisphosphonate inhibition of wear debris-induced osteolysis assessed by longitudinal micro-CT. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Yazici CYanoso LXie CReynolds DGSamulski RJSamulski JYannariello-Brown JGertzman AAZhang XAwad HASchwarz EM (2008 Oct). The effect of surface demineralization of cortical bone allograft on the properties of recombinant adeno-associated virus coatings. Biomaterials. Wu QKim KOSampson ERChen DAwad HO'Brien TPuzas JEDrissi HSchwarz EMO'Keefe RJZuscik MJRosier RN (2008 Oct). Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice. Arthritis and rheumatism. Kaback LASoung do YNaik AGeneau GSchwarz EMRosier RNO'Keefe RJDrissi H (2008 Sep 1). Teriparatide (1-34 human PTH) regulation of osterix during fracture repair. Journal of cellular biochemistry. Guo RYamashita MZhang QZhou QChen DReynolds DGAwad HAYanoso LZhao LSchwarz EMZhang YEBoyce BFXing L (2008 Aug 22). Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins. The Journal of biological chemistry. Zhang XAwad HAO'Keefe RJGuldberg RESchwarz EM (2008 Aug). A perspective: engineering periosteum for structural bone graft healing. Clinical orthopaedics and related research. Mensah KASchwarz EMRitchlin CT (2008 Aug). Altered bone remodeling in psoriatic arthritis. Current rheumatology reports. Proulx STKwok EYou ZPapuga MOBeck CAShealy DJCalvi LMRitchlin CTAwad HABoyce BFXing LSchwarz EM (2008 Jul). Elucidating bone marrow edema and myelopoiesis in murine arthritis using contrast-enhanced magnetic resonance imaging. Arthritis and rheumatism. Eliseev RADong YFSampson EZuscik MJSchwarz EMO'Keefe RJRosier RNDrissi MH (2008 Jun 5). Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis. Oncogene. Hasslund SJacobson JADadali TBasile PUlrich-Vinther MSøballe KSchwarz EMO'Keefe RJMitten DJAwad HA (2008 Jun). Adhesions in a murine flexor tendon graft model: autograft versus allograft reconstruction. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Zhang QGuo RLu YZhao LZhou QSchwarz EMHuang JChen DJin ZGBoyce BFXing L (2008 May 9). VEGF-C, a lymphatic growth factor, is a RANKL target gene in osteoclasts that enhances osteoclastic bone resorption through an autocrine mechanism. The Journal of biological chemistry. Yao ZXing LQin CSchwarz EMBoyce BF (2008 Apr 11). Osteoclast precursor interaction with bone matrix induces osteoclast formation directly by an interleukin-1-mediated autocrine mechanism. The Journal of biological chemistry. Basile PDadali TJacobson JHasslund SUlrich-Vinther MSøballe KNishio YDrissi MHLangstein HNMitten DJO'Keefe RJSchwarz EMAwad HA (2008 Mar). Freeze-dried tendon allografts as tissue-engineering scaffolds for Gdf5 gene delivery. Molecular therapy : the journal of the American Society of Gene Therapy. Anandarajah APSchwarz EMTotterman SMonu JFeng CYShao THaas-Smith SARitchlin CT (2008 Mar). The effect of etanercept on osteoclast precursor frequency and enhancing bone marrow oedema in patients with psoriatic arthritis. Annals of the rheumatic diseases. Xie CXue MWang QSchwarz EMO'Keefe RJZhang X (2008 Feb). Tamoxifen-inducible CreER-mediated gene targeting in periosteum via bone-graft transplantation. The Journal of bone and joint surgery. American volume. Li DGromov KSøballe KPuzas JEO'Keefe RJAwad HDrissi HSchwarz EM (2008 Jan). Quantitative mouse model of implant-associated osteomyelitis and the kinetics of microbial growth, osteolysis, and humoral immunity. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Zhang QGuo RSchwarz EMBoyce BFXing L (2008). TNF inhibits production of stromal cell-derived factor 1 by bone stromal cells and increases osteoclast precursor mobilization from bone marrow to peripheral blood. Arthritis research & therapy. Kaback LASoung do YNaik ASmith NSchwarz EMO'Keefe RJDrissi H (2008 Jan). Osterix/Sp7 regulates mesenchymal stem cell mediated endochondral ossification. Journal of cellular physiology. Schwarz EM (2008). What potential biologic treatments are available for osteolysis? The Journal of the American Academy of Orthopaedic Surgeons. Proulx STKwok EYou ZPapuga MOBeck CAShealy DJRitchlin CTAwad HABoyce BFXing LSchwarz EM (2007 Dec). Longitudinal assessment of synovial, lymph node, and bone volumes in inflammatory arthritis in mice by in vivo magnetic resonance imaging and microfocal computed tomography. Arthritis and rheumatism. Proulx STKwok EYou ZBeck CAShealy DJRitchlin CTBoyce BFXing LSchwarz EM (2007 Nov). MRI and quantification of draining lymph node function in inflammatory arthritis. Annals of the New York Academy of Sciences. Boyce BFYao ZZhang QGuo RLu YSchwarz EMXing L (2007 Nov). New roles for osteoclasts in bone. Annals of the New York Academy of Sciences. Dong YFSoung do YChang YEnomoto-Iwamoto MParis MO'Keefe RJSchwarz EMDrissi H (2007 Nov). Transforming growth factor-beta and Wnt signals regulate chondrocyte differentiation through Twist1 in a stage-specific manner. Molecular endocrinology (Baltimore, Md.). Zuscik MJMa LBuckley TPuzas JEDrissi HSchwarz EMO'Keefe RJ (2007 Sep). Lead induces chondrogenesis and alters transforming growth factor-beta and bone morphogenetic protein signaling in mesenchymal cell populations. Environmental health perspectives. Awad HAZhang XReynolds DGGuldberg REO'Keefe RJSchwarz EM (2007 Aug). Recent advances in gene delivery for structural bone allografts. Tissue engineering. Soung do YDong YWang YZuscik MJSchwarz EMO'Keefe RJDrissi H (2007 Aug). Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Yamashita TYao ZLi FZhang QBadell IRSchwarz EMTakeshita SWagner EFNoda MMatsuo KXing LBoyce BF (2007 Jun 22). NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1. The Journal of biological chemistry. Xie CReynolds DAwad HRubery PTPelled GGazit DGuldberg RESchwarz EMO'Keefe RJZhang X (2007 Mar). Structural bone allograft combined with genetically engineered mesenchymal stem cells as a novel platform for bone tissue engineering. Tissue engineering. Reynolds DGHock CShaikh SJacobson JZhang XRubery PTBeck CAO'keefe RJLerner ALSchwarz EMAwad HA (2007). Micro-computed tomography prediction of biomechanical strength in murine structural bone grafts. Journal of biomechanics. Zhang QLu YProulx STGuo RYao ZSchwarz EMBoyce BFXing L (2007). Increased lymphangiogenesis in joints of mice with inflammatory arthritis. Arthritis research & therapy. Schwarz EMRitchlin CT (2007). Clinical development of anti-RANKL therapy. Arthritis research & therapy. Robertson GXie CChen DAwad HSchwarz EMO'Keefe RJGuldberg REZhang X (2006 Oct). Alteration of femoral bone morphology and density in COX-2-/- mice. Bone. Li TFChen DWu QChen MSheu TJSchwarz EMDrissi HZuscik MO'Keefe RJ (2006 Jul 28). Transforming growth factor-beta stimulates cyclin D1 expression through activation of beta-catenin signaling in chondrocytes. The Journal of biological chemistry. Boyce BFSchwarz EMXing L (2006 Jul). Osteoclast precursors: cytokine-stimulated immunomodulators of inflammatory bone disease. Current opinion in rheumatology. Dong YFSoung do YSchwarz EMO'Keefe RJDrissi H (2006 Jul). Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor. Journal of cellular physiology. Wood RWBaggs RBSchwarz EMMessing EM (2006 Jun). Initial observations of reduced uroflow in transgenic adenocarcinoma of murine prostate. Urology. Nishio YDong YParis MO'Keefe RJSchwarz EMDrissi H (2006 May 10). Runx2-mediated regulation of the zinc finger Osterix/Sp7 gene. Gene. Yao ZLi PZhang QSchwarz EMKeng PArbini ABoyce BFXing L (2006 Apr 28). Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression. The Journal of biological chemistry. Schwarz EMLooney RJDrissi MHO'Keefe RJBoyce BFXing LRitchlin CT (2006 Apr). Autoimmunity and bone. Annals of the New York Academy of Sciences. Maloney MDGoater JJParsons RIto HO'Keefe RJRubery PTDrissi MHSchwarz EM (2006 Apr). Safety and efficacy of ultraviolet-a light-activated gene transduction for gene therapy of articular cartilage defects. The Journal of bone and joint surgery. American volume. O'Keefe RJTiyapatanaputi PXie CLi TFClark CZuscik MJChen DDrissi HSchwarz EZhang X (2006 Apr). COX-2 has a critical role during incorporation of structural bone allografts. Annals of the New York Academy of Sciences. Kaneki HGuo RChen DYao ZSchwarz EMZhang YEBoyce BFXing L (2006 Feb 17). Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts. The Journal of biological chemistry. Anandarajah APSchwarz EM (2006 Feb 1). Anti-RANKL therapy for inflammatory bone disorders: Mechanisms and potential clinical applications. Journal of cellular biochemistry. Eliseev RASchwarz EMZuscik MJO'Keefe RJDrissi HRosier RN (2006 Jan 1). Smad7 mediates inhibition of Saos2 osteosarcoma cell differentiation by NFkappaB. Experimental cell research. Looney RJSchwarz EMBoyd AO'Keefe RJ (2006 Jan). Periprosthetic osteolysis: an immunologist's update. Current opinion in rheumatology. Li TFDarowish MZuscik MJChen DSchwarz EMRosier RNDrissi HO'Keefe RJ (2006 Jan). Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Andela VBSchwarz EMO'Keefe RJPuzas EJRosenblatt JDRosier RN (2005 Dec 19). A genome-wide expression profile and system-level integration of nuclear factor kappa B regulated genes reveals fundamental metabolic adaptations during cell growth and survival. FEBS letters. Eliseev RAZuscik MJSchwarz EMO'Keefe RJDrissi HRosier RN (2005 Dec 15). Increased radiation-induced apoptosis of Saos2 cells via inhibition of NFkappaB: a role for c-Jun N-terminal kinase. Journal of cellular biochemistry. Zhang XXie CLin ASIto HAwad HLieberman JRRubery PTSchwarz EMO'Keefe RJGuldberg RE (2005 Dec). Periosteal progenitor cell fate in segmental cortical bone graft transplantations: implications for functional tissue engineering. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Xing LSchwarz EMBoyce BF (2005 Dec). Osteoclast precursors, RANKL/RANK, and immunology. Immunological reviews. Soloviev ASchwarz EMDarowish MO'Keefe RJ (2005 Nov). Sphingomyelinase mediates macrophage activation by titanium particles independent of phagocytosis: a role for free radicals, NFkappaB, and TNFalpha. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Zhang QBadell IRSchwarz EMBoulukos KEYao ZBoyce BFXing L (2005 Sep). Tumor necrosis factor prevents alendronate-induced osteoclast apoptosis in vivo by stimulating Bcl-xL expression through Ets-2. Arthritis and rheumatism. Boyce BFLi PYao ZZhang QBadell IRSchwarz EMO'Keefe RJXing L (2005 Sep). TNF-alpha and pathologic bone resorption. The Keio journal of medicine. Wang YBelflower RMDong YFSchwarz EMO'Keefe RJDrissi H (2005 Sep). Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Koefoed MIto HGromov KReynolds DGAwad HARubery PTUlrich-Vinther MSoballe KGuldberg RELin ASO'Keefe RJZhang XSchwarz EM (2005 Aug). Biological effects of rAAV-caAlk2 coating on structural allograft healing. Molecular therapy : the journal of the American Society of Gene Therapy. Dong YDrissi HChen MChen DZuscik MJSchwarz EMO'Keefe RJ (2005 Aug 1). Wnt-mediated regulation of chondrocyte maturation: modulation by TGF-beta. Journal of cellular biochemistry. Mandelin JLiljeström MLi TFAinola MHukkanen MSalo JSantavirta SKonttinen YT (2005 Jul). Pseudosynovial fluid from loosened total hip prosthesis induces osteoclast formation. Journal of biomedical materials research. Part B, Applied biomaterials. Wei XZhang XZuscik MJDrissi MHSchwarz EMO'Keefe RJ (2005 Jul). Fibroblasts express RANKL and support osteoclastogenesis in a COX-2-dependent manner after stimulation with titanium particles. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Carmouche JJPuzas JEZhang XTiyapatanaputi PCory-Slechta DAGelein RZuscik MRosier RNBoyce BFO'Keefe RJSchwarz EM (2005 Jun). Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency. Environmental health perspectives. Gordon AHO'Keefe RJSchwarz EMRosier RNPuzas JE (2005 Apr 15). Nuclear factor-kappaB-dependent mechanisms in breast cancer cells regulate tumor burden and osteolysis in bone. Cancer research. Smith NDong YLian JBPratap JKingsley PDvan Wijnen AJStein JLSchwarz EMO'Keefe RJStein GSDrissi MH (2005 Apr). Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. Journal of cellular physiology. Mandelin JLi TFHukkanen MLiljeström MSalo JSantavirta SKonttinen YT (2005 Apr). Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K. The Journal of rheumatology. Clark CASchwarz EMZhang XZiran NMDrissi HO'Keefe RJZuscik MJ (2005 Mar 18). Differential regulation of EP receptor isoforms during chondrogenesis and chondrocyte maturation. Biochemical and biophysical research communications. Ito HKoefoed MTiyapatanaputi PGromov KGoater JJCarmouche JZhang XRubery PTRabinowitz JSamulski RJNakamura TSoballe KO'Keefe RJBoyce BFSchwarz EM (2005 Mar). Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy. Nature medicine. Yu SZhang XHe ZLiu Y (2005 Feb). [Corrosiveness of Ti-Fe-Mo-Mn-Nb-Zr alloys in various pH lactic acids]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. Li TFO'Keefe RJChen D (2005 Jan 1). TGF-beta signaling in chondrocytes. Frontiers in bioscience : a journal and virtual library. Schwarz EMO'Keefe RJLooney RJ (2004 Dec). Bone implant interface, osteolysis and potential therapies. Journal of musculoskeletal & neuronal interactions. Guldberg REOest MLin ASIto HChao XGromov KGoater JJKoefoed MSchwarz EMO'Keefe RJZhang X (2004 Dec). Functional integration of tissue-engineered bone constructs. Journal of musculoskeletal & neuronal interactions. Tiyapatanaputi PRubery PTCarmouche JSchwarz EMO'keefe RJZhang X (2004 Nov). A novel murine segmental femoral graft model. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Anandarajah APSchwarz EM (2004 Nov). Dynamic exercises in patients with rheumatoid arthritis. Annals of the rheumatic diseases. Li TFZuscik MJIonescu AMZhang XRosier RNSchwarz EMDrissi HO'Keefe RJ (2004 Oct 15). PGE2 inhibits chondrocyte differentiation through PKA and PKC signaling. Experimental cell research. Li TFDong YIonescu AMRosier RNZuscik MJSchwarz EMO'Keefe RJDrissi H (2004 Sep 10). Parathyroid hormone-related peptide (PTHrP) inhibits Runx2 expression through the PKA signaling pathway. Experimental cell research. Ritchlin CTSchwarz EMO'Keefe RJLooney RJ (2004 Sep). RANK, RANKL and OPG in inflammatory arthritis and periprosthetic osteolysis. Journal of musculoskeletal & neuronal interactions. Leung YYSchwarz EMSilvers CRMessing EMWood RW (2004 Aug). Uroflow in murine urethritis. Urology. Ferguson CMSchwarz EMPuzas JEZuscik MJDrissi HO'Keefe RJ (2004 Jul). Transforming growth factor-beta1 induced alteration of skeletal morphogenesis in vivo. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Ulrich-Vinther MDuch MRSøballe KO'Keefe RJSchwarz EMPedersen FS (2004 Jul). In vivo gene delivery to articular chondrocytes mediated by an adeno-associated virus vector. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Zuscik MJBaden JFWu QSheu TJSchwarz EMDrissi HO'Keefe RJPuzas JERosier RN (2004 May 15). 5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes. Journal of cellular biochemistry. Zhang XZiran NGoater JJSchwarz EMPuzas JERosier RNZuscik MDrissi HO'Keefe RJ (2004 May). Primary murine limb bud mesenchymal cells in long-term culture complete chondrocyte differentiation: TGF-beta delays hypertrophy and PGE2 inhibits terminal differentiation. Bone. Ionescu AMDrissi HSchwarz EMKato MPuzas JEMcCance DJRosier RNZuscik MJO'Keefe RJ (2004 Mar). CREB Cooperates with BMP-stimulated Smad signaling to enhance transcription of the Smad6 promoter. Journal of cellular physiology. Li PSchwarz EMO'Keefe RJMa LBoyce BFXing L (2004 Feb). RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Yu SZhang XHe ZGao ZWang C (2004 Feb). [The influence of Ce on microstructures and mechanics performances of Ti-Fe-Mo-Mn-Nb-Zr alloys]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. Li PSchwarz EMO'Keefe RJMa LLooney RJRitchlin CTBoyce BFXing L (2004 Jan). Systemic tumor necrosis factor alpha mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor alpha-transgenic mice. Arthritis and rheumatism. Bukata SVGelinas JWei XRosier RNPuzas JEZhang XSchwarz EMSong XYGriswold DEO'Keefe RJ (2004 Jan). PGE2 and IL-6 production by fibroblasts in response to titanium wear debris particles is mediated through a Cox-2 dependent pathway. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Ito HGoater JJTiyapatanaputi PRubery PTO'Keefe RJSchwarz EM (2004 Jan). Light-activated gene transduction of recombinant adeno-associated virus in human mesenchymal stem cells. Gene therapy. Drissi MHLi XSheu TJZuscik MJSchwarz EMPuzas JERosier RNO'Keefe RJ (2003 Dec 15). Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes. Journal of cellular biochemistry. Huang WDrissi MHO'Keefe RJSchwarz EM (2003 Dec). A rapid multiparameter approach to study factors that regulate osteoclastogenesis: demonstration of the combinatorial dominant effects of TNF-alpha and TGF-ss in RANKL-mediated osteoclastogenesis. Calcified tissue international. Puzas JEO'Keefe RJSchwarz EMZhang X (2003 Dec). Pharmacologic modulators of fracture healing: the role of cyclooxygenase inhibition. Journal of musculoskeletal & neuronal interactions. Schwarz EMCampbell DTotterman SBoyd AO'Keefe RJLooney RJ (2003 Nov). Use of volumetric computerized tomography as a primary outcome measure to evaluate drug efficacy in the prevention of peri-prosthetic osteolysis: a 1-year clinical pilot of etanercept vs. placebo. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Ulrich-Vinther MMaloney MDSchwarz EMRosier RO'Keefe RJ (2003 Nov). Articular cartilage biology. The Journal of the American Academy of Orthopaedic Surgeons. Andela VBPirri MSchwarz EMPuzas EJO'Keefe RJRosenblatt JDRosier RN (2003 Oct). The mevalonate synthesis pathway as a therapeutic target in cancer. Clinical orthopaedics and related research. Andela VBGordon AHZotalis GRosier RNGoater JJLewis GDSchwarz EMPuzas JEO'Keefe RJ (2003 Oct). NFkappaB: a pivotal transcription factor in prostate cancer metastasis to bone. Clinical orthopaedics and related research. Li XIonescu AMSchwarz EMZhang XDrissi HPuzas JERosier RNZuscik MJO'Keefe RJ (2003 Sep). Smad6 is induced by BMP-2 and modulates chondrocyte differentiation. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Zhang DSchwarz EMRosier RNZuscik MJPuzas JEO'Keefe RJ (2003 Sep). ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. Ionescu AMSchwarz EMZuscik MJDrissi HPuzas JERosier RNO'Keefe RJ (2003 Aug 1). ATF-2 cooperates with Smad3 to mediate TGF-beta effects on chondrocyte maturation. Experimental cell research. Li PSchwarz EM (2003 Aug). The TNF-alpha transgenic mouse model of inflammatory arthritis. Springer seminars in immunopathology. Flick LMWeaver JMUlrich-Vinther MAbuzzahab FZhang XDougall WCAnderson DO'Keefe RJSchwarz EM (2003 Jul). Effects of receptor activator of NFkappaB (RANK) signaling blockade on fracture healing. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Li XSchwarz EMZuscik MJRosier RNIonescu AMPuzas JEDrissi HSheu TJO'Keefe RJ (2003 Jun). Retinoic acid stimulates chondrocyte differentiation and enhances bone morphogenetic protein effects through induction of Smad1 and Smad5. Endocrinology. Andela VBGingold BISouza MDO'Keefe RJPuzas EJSchwarz EMRosier RN (2003 May 8). Clinical relevance of increased retinoid and cAMP transcriptional programs in tumor cells rendered non-malignant by dominant negative inhibition of NFkappaB. Cancer letters. Ritchlin CTHaas-Smith SALi PHicks DGSchwarz EM (2003 Mar). Mechanisms of TNF-alpha- and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis. The Journal of clinical investigation. Sheu TJSchwarz EMMartinez DAO'Keefe RJRosier RNZuscik MJPuzas JE (2003 Jan 3). A phage display technique identifies a novel regulator of cell differentiation. The Journal of biological chemistry. Huang WO'Keefe RJSchwarz EM (2003). Exposure to receptor-activator of NFkappaB ligand renders pre-osteoclasts resistant to IFN-gamma by inducing terminal differentiation. Arthritis research & therapy. Huang WSchwarz EM (2002 Dec). Mechanisms of bone resorption and new bone formation in spondyloarthropathies. Current rheumatology reports. Andela VBSheu TJPuzas EJSchwarz EMO'Keefe RJRosier RN (2002 Sep 20). Malignant reversion of a human osteosarcoma cell line, Saos-2, by inhibition of NFkappaB. Biochemical and biophysical research communications. Zuscik MJO'Keefe RJGunter TEPuzas JESchwarz EMRosier RN (2002 Sep). Parathyroid hormone-related peptide regulation of chick tibial growth plate chondrocyte maturation requires protein kinase A. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Ulrich-Vinther MCarmody EEGoater JJS balle KO'Keefe RJSchwarz EM (2002 Aug). Recombinant adeno-associated virus-mediated osteoprotegerin gene therapy inhibits wear debris-induced osteolysis. The Journal of bone and joint surgery. American volume. Ulrich-Vinther MMaloney MDGoater JJSøballe KGoldring MBO'Keefe RJSchwarz EM (2002 Aug). Light-activated gene transduction enhances adeno-associated virus vector-mediated gene expression in human articular chondrocytes. Arthritis and rheumatism. Soloviev ASchwarz EMKuprash DVNedospasov SAPuzas JERosier RNO'Keefe RJ (2002 Jul). The role of p105 protein in NFkappaB activation in ANA-1 murine macrophages following stimulation with titanium particles. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Zuscik MJPateder DBPuzas JESchwarz EMRosier RNO'Keefe RJ (2002 Jul). Lead alters parathyroid hormone-related peptide and transforming growth factor-beta1 effects and AP-1 and NF-kappaB signaling in chondrocytes. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. Zuscik MJD'Souza MIonescu AMGunter KKGunter TEO'Keefe RJSchwarz EMPuzas JERosier RN (2002 Jun 10). Growth plate chondrocyte maturation is regulated by basal intracellular calcium. Experimental cell research. Zhang XSchwarz EMYoung DAPuzas JERosier RNO'Keefe RJ (2002 Jun). Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. The Journal of clinical investigation. O'Keefe RJ (2002 Jun). Determination of responsiveness in biological systems is dependent on highly sensitive quantitative measures. Annals of the New York Academy of Sciences.