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URMC / Labs / Tivarus Lab / Projects / Functional connectivity in the brain using resting state fMRI in patients with brain tumors

Functional connectivity in the brain using resting state fMRI in patients with brain tumors

This project seeks to evaluate if language lateralization obtained from resting state fMRI can replace standard assessment using task fMRI. We also ask how functional connections in the brain are altered by brain lesions and their locations in the brain, and how these may influence the language lateralization assessment.

Language laterality index

Figure 1: Language Laterality Index, t-fMRI and rs-fMRI.

Regions with higher FC

Figure 2: Regions with higher FC in healthy controls and higher FC in patients with tumors in the left hemisphere (than in the right hemisphere).