URMC / Labs / Xu Lab / Publications Recent Publications Chandrasekaran SGiang UBXu LDeLouise LA (2016 Oct). In vitro assays for determining the metastatic potential of melanoma cell lines with characterized in vivo invasiveness. Biomedical microdevices. Tiwary SXu L (2016). FRIZZLED7 Is Required for Tumor Initiation and Metastatic Growth of Melanoma Cells. PloS one. Stoveken HMHajduczok AGXu LTall GG (2015 May 12). Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist. Proceedings of the National Academy of Sciences of the United States of America. Hamann JAust GAraç DEngel FBFormstone CFredriksson RHall RAHarty BLKirchhoff CKnapp BKrishnan ALiebscher ILin HHMartinelli DCMonk KRPeeters MCPiao XPrömel SSchöneberg TSchwartz TWSinger KStacey MUshkaryov YAVallon MWolfrum UWright MWXu LLangenhan TSchiöth HB (2015). International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. Pharmacological reviews. Liebscher IAckley BAraç DAriestanti DMAust GBae BIBista BRBridges JPDuman JGEngel FBGiera SGoffinet AMHall RAHamann JHartmann NLin HHLiu MLuo RMogha AMonk KRPeeters MCPrömel SRessl SSchiöth HBSigoillot SMSong HTalbot WSTall GGWhite JPWolfrum UXu LPiao X (2014 Dec). New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors. Annals of the New York Academy of Sciences. Yang LFriedland SCorson NXu L (2014 Feb 15). GPR56 inhibits melanoma growth by internalizing and degrading its ligand TG2. Cancer research. Tiwary SPreziosi MRothberg PGZeitouni NCorson NXu L (2014). ERBB3 is required for metastasis formation of melanoma cells. Oncogenesis. Chen YSoong JMohanty SXu LScott G (2013 Oct 10). The neural guidance receptor Plexin C1 delays melanoma progression. Oncogene. Araç DAust GCalebiro DEngel FBFormstone CGoffinet AHamann JKittel RJLiebscher ILin HHMonk KRPetrenko APiao XPrömel SSchiöth HBSchwartz TWStacey MUshkaryov YAWobus MWolfrum UXu LLangenhan T (2012 Dec). Dissecting signaling and functions of adhesion G protein-coupled receptors. Annals of the New York Academy of Sciences. Yang LXu L (2012 Apr). GPR56 in cancer progression: current status and future perspective. Future oncology (London, England). Yang LChen GMohanty SScott GFazal FRahman ABegum SHynes ROXu L (2011 Aug 15). GPR56 Regulates VEGF production and angiogenesis during melanoma progression. Cancer research. Dimond PCarlson KBouvier MGerard CXu LCovic LAgarwal AErnst OPJanz JMSchwartz TWGardella TJMilligan GKuliopulos ASakmar TPHunt SW (2011 May). G protein-coupled receptor modulation with pepducins: moving closer to the clinic. Annals of the New York Academy of Sciences. Xu LBegum SBarry MCrowley DYang LBronson RTHynes RO (2010 Apr). GPR56 plays varying roles in endogenous cancer progression. Clinical & experimental metastasis. Mohanty SXu L (2010). Experimental metastasis assay. Journal of visualized experiments : JoVE. Xu L (2010). GPR56 interacts with extracellular matrix and regulates cancer progression. Advances in experimental medicine and biology. Chen GYang LBegum SXu L (2010 Jan 01). GPR56 Is Essential for Testis Development and Male Fertility in Mice. Developmental Dynamics. Li SJin ZKoirala SBu LXu LHynes ROWalsh CACorfas GPiao X (2008 May 28). GPR56 regulates pial basement membrane integrity and cortical lamination. The Journal of neuroscience : the official journal of the Society for Neuroscience. Xu LShen SSHoshida YSubramanian ARoss KBrunet JPWagner SNRamaswamy SMesirov JPHynes RO (2008 May). Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases. Molecular cancer research : MCR. Xu LHynes RO (2007 Jan 15). GPR56 and TG2: possible roles in suppression of tumor growth by the microenvironment. Cell cycle (Georgetown, Tex.). Xu LBegum SHearn JDHynes RO (2006 Jun 13). GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis. Proceedings of the National Academy of Sciences of the United States of America. Xu LPaulsen JYoo YGoodwin EBStrome S (2001 Nov). Caenorhabditis elegans MES-3 is a target of GLD-1 and functions epigenetically in germline development. Genetics. Xu LStrome S (2001 Nov). Depletion of a novel SET-domain protein enhances the sterility of mes-3 and mes-4 mutants of Caenorhabditis elegans. Genetics. Xu LFong YStrome S (2001 Apr 24). The Caenorhabditis elegans maternal-effect sterile proteins, MES-2, MES-3, and MES-6, are associated in a complex in embryos. Proceedings of the National Academy of Sciences of the United States of America. Williams CXu LBlumenthal T (1999 Jan). SL1 trans splicing and 3'-end formation in a novel class of Caenorhabditis elegans operon. Molecular and cellular biology.