Alex Rosenberg Alexander Rosenberg, Ph.D. View Dr. Rosenberg's profile Ph.D. 1993 University of Pittsbugh Research Assistant Professor Division of Allergy/Immunology and Rheumatology Research Overview Dr. Rosenberg's group provides bioinformatics expertise and services through collaborations with many investigators within the University of Rochester Medical Center as well as through the Data Visualization and Bioinformatics Service Center that he runs. His team works with many data-rich platforms including gene expression microarrays, next-generation sequencing (including RNAseq and B cell repertoire analysis) and multi-parameter flow cytometry. He is involved with many aspects of bioinformatics, from data modeling, database development, and software pipelines for high-throughput workflows through analysis and visualization of complex data sets. Dr. Rosenberg is part of the Rochester Center for Health Informatics where he works on network analysis and visualization of high-dimensional data. Select Publications Tipton CM; Fucile CF; Darce J; Chida A; Ichikawa T; Gregoretti I; Schieferl S; Hom J; Jenks S; Feldman RJ; Mehr R; Wei C; Lee FE; Cheung WC; Rosenberg AF; Sanz I. "Diversity, cellular origin and auto reactivity of antibody-secreting cell expansions in acute systemic lupus erythematosus". Nature Immunology. 2015; : In press. Rosenberg A, Fan H, Chiu YG, Bolce R, Tabechian D, Barrett R, Moorehead S, Baribaud F, Liu H, Peffer N, Shealy D, Schwarz EM, Ritchlin CT. "Divergent gene activation in peripheral blood and tissues of patients with rheumatoid arthritis, psoriatic arthritis and psoriasis following infliximab therapy." PloS one. 2014 9(10):e110657. Epub 2014 Oct 21. Roberts ME, Kaminski D, Jenks SA, Maguire C, Ching K, Burbelo PD, Iadarola M, Rosenberg A, Coca A, Anolik J, Sanz I. "Primary Sjögren's syndrome is characterized by distinct phenotypic and transcriptional profiles of IgD+ unswitched memory B cells." Arthritis & rheumatology. 2014 Sep; 66(9):2558-69. Palanichamy A, Bauer JW, Yalavarthi S, Meednu N, Barnard J, Owen T, Cistrone C, Bird A, Rabinovich A, Nevarez S, Knight JS, Dedrick R, Rosenberg A, Wei C, Rangel-Moreno J, Liesveld J, Sanz I, Baechler E, Kaplan MJ, Anolik JH. "Neutrophil-mediated IFN activation in the bone marrow alters B cell development in human and murine systemic lupus erythematosus." The Journal of immunology : official journal of the American Association of Immunologists. 2014 Feb 1; 192(3):906-18. Epub 2013 Dec 30. Hilchey SP, Rosenberg AF, Hyrien O, Secor-Socha S, Cochran MR, Brady MT, Wang JC, Sanz I, Burack WR, Quataert SA, Bernstein SH. "Follicular lymphoma tumor-infiltrating T-helper (T(H)) cells have the same polyfunctional potential as normal nodal T(H) cells despite skewed differentiation." Blood. 2011 Sep 29; 118(13):3591-602. Epub 2011 Aug 05.