Core Center Grant (P30)

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) recently awarded a Research Core Center (P30) in musculoskeletal biology and medicine to theUniversity of Rochester, which runs from August 2011 through July 2016. This URCCMBM, which is led by Dr. Edward Schwarz (Director) and Dr. Michael Zuscik (Co-Director), provides shared facilities and services to groups of established, currently funded investigators addressing scientific problems in musculoskeletal biology and medicine, in order to improve efficiency, accelerate the pace of research, and ensure greater productivity. Additionally, through its unique Enrichment Program designed to expand the research base, the URCCMBM aims to facilitate the development and promotion of Research Assistant Professors and New Physician-Scientists. There are three Cores. The Administrative Core oversees the entire program and run the Enrichment Program that includes: a Mentoring sub-Core, a Clinical Research sub-Core, a Visiting Professor Program, Travel Grants and an Annual Research Symposium.The Histology, Biochemistry, and Molecular Imaging (HBMI) Core, which is led by Dr. Jennifer Jonason (Director) and Dr. Brendan Boyce (Co-Director), will facilitate cellular and molecular assays, histology and morphometry. The Biomechanics and Multimodal Tissue Imaging (BMTI) Core, which is run by Dr. Hani Awad (Director) and Dr. Edward Puzas (Co-Director), will facilitate in vivotranslational research (mechanical testing, micro-CT, in vivo multispectral and ultrasound imaging). The URCCMBM is heavily leveraged by institutional support from the School of Medicine & Dentistry and the NIH funded CTSI. Finally, the URCCMBMB will award pilot project grants (four $25,000 grants per year) to Physician-Scientists and Research Assistant Professors who have not received NIH R01 or equivalent grant funding as Principal Investigator, for research aimed at improving the diagnosis, treatment and prevention of diseases and injuries of the musculoskeletal system and its component tissues. Key public health problems addressed by this research include, but are not limited to osteoporosis, osteoarthritis, and muscular dystrophies. The URCCMBM intends to combine and provide additional resources for research into these areas of human health.


Core Center

Upcoming Speakers

February 9, 2016 - Special Lab Meeting (Adolph Auditorium, Rm. 1-7619 (8:30-9:30 am)

Yunpeng Yang - Identification of the effective sources of vascular progenitors for bone tissue engineering
Tao Wang - Electrospun Nanofiber-Based Biomimetic Periosteum for Cranial Bone Defect Repair

February 10, 2016 (Neuman Room, Rm 1-6823 (8:30-9:30 am)

Javier Rangel-Moreno - Small Inhibitors of nuclear export deplete autoreactive plasma cells in murine lupus
Wen Sun - B cells inhibit osteoblast differentiation in inflammatory arthritis


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