July 22, 2015
Brian Ho wins scholarship competition
Brian's work showing axons originating from cells in the bed nucleus of the stria terminalis overlying the
dorsal tiersubpopulation of dopamine cells (pink dots).
Congratulations to Brian Ho, a rising senior at the University of Rochester, who has been in the Fudge lab since January. Brian was the winner of a competition sponsored by Delta Sonic, that assists promising students with a cash scholarship. In our lab, Brian's work focuses on how brain regions involved in threat responses, such as the bed nucleus of the stria terminalis and central amygdala nucleus, interact with specific dopamine neuron subpopulations.
July 22, 2015
Danielle deCampo makes the move with Golisano Children's Hospital
Danielle is completing a sub-internship in Pediatrics this summer--and they moved the hospital! The amazing undertaking of relocating from the old Pediatrics ward to beautiful new building took everyone's efforts. (Danielle is second from right).
July 20, 2015
Infants can use their expectations about the world to rapidly shape their developing brains, researchers have found.
A series of experiments with infants 5 to 7 months old has shown that portions of babies' brains responsible for visual processing respond not just to the presence of visual stimuli, but also to the mere expectation of visual stimuli, according to researchers from the University of Rochester and the University of South Carolina.
That type of complex neural processing was once thought to happen only in adults—not infants—whose brains are still developing important neural connections.
We show that in situations of learning and situations of expectations, babies are in fact able to really quickly use their experience to shift the ways different areas of their brain respond to the environment,said Lauren Emberson, who conducted the study at the University of Rochester's Baby Lab while a research associate with Richard Aslin in the department of brain and cognitive sciences.
For more information, visit the University of Rochester Newscenter.
July 7, 2015
Researcher Wins Auditory Neuroscience Award
Laurel Carney, a professor of Biomedical Engineering, has been recognized for her work by the premier scientific organization in the field of acoustics. The Acoustical Society of America has awarded Carney the William and Christine Hartmann Prize in Auditory Neuroscience.
It's truly a great honor to receive an award created by Bill and Christine Hartmann, two of my role models,said Carney.
I welcome the challenge to emulate their life of discovery, presentation, publication, service, and education throughout the world.
William and Christine Hartmann established the award with a donation to recognize and honor
research that links auditory physiology with auditory perception or behavior in humans or other animals.William Hartmann is a physicist, psychoacoustician, and former president of the Acoustical Society of America. His contributions to the field involved pitch perception, signal detection, modulation detection, and the localization of sound.
In her research lab, Carney is working to better understand how the brain translates sounds into patterns of electrical impulses. By studying physiology, human hearing, and computer models, Carney hopes to learn how the brain distinguishes sounds in noisy environments and why even a small degree of hearing loss can lead to major problems. Her ultimate goal is to develop effective strategies to help people who have experienced hearing loss.
Carney earned her M.S. and Ph.D. degrees in electrical engineering at the University of Wisconsin-Madison. She was an associate professor of biomedical engineering at Boston University and professor of biomedical engineering at Syracuse University before joining the faculty at the University of Rochester in 2007, where she serves as professor in three departments—biomedical engineering, neurobiology and anatomy, and electrical and computer engineering.
For additional information, visit the Rochester Newsroom.
July 1, 2015
Mink Receives First Ever Tourette’s Association of America Award
Jonathan Mink, M.D., Ph.D., chief of Child Neurology at Golisano Children’s Hospital, is the first recipient of the Tourette Association of America’s Oliver Sacks Award for Excellence. The award, named for the famous British neurologist, was to be presented at the First World Congress on Tourette Syndrome and Tic Disorders, but due to a scheduling conflict, representatives from TAA instead traveled to Rochester to present him with the award in a surprise ceremony.
The award is in recognition of his many years of leadership, mentorship, research, and care on behalf of all people touched by Tourette syndrome and tic disorders around the world.
June 22, 2015
Two NGP students are presenting their defense seminars next week.
Wei Sun defends on Monday June 29th and Adam Pallus defends on July 1st
To read their abstracts, visit the Defense Seminars site.
June 14, 2015
Kerry O'Banion, interim chair of the Department of Neurobiology and Anatomy, and University President Emeritus Thomas Jackson will present
Patent Infringement: COX Fighting, from noon to 1 p.m. Wednesday, June 17, in Helen Wood Hall Auditorium. The event is part of the CTSI workshop series,
Good Advice: Case Studies in Clinical Research, Regulation, and the Law.
June 10, 2015
Laurel Carney, Ph.D.
Laurel H. Carney has been awarded the William and Christine Hartmann Prize in Auditory Neuroscience by the Acoustical Society of America (ASA). The award was presented at the 169th meeting of the ASA on 20 May 2015 in Pittsburgh, Pennsylvania.
The William and Christine Hartmann Prize in Auditory Neuroscience was established in 2011 through a generous donation by Bill and Chris Hartmann to the Acoustical Society of America to recognize and honor research that links auditory physiology with auditory perception or behavior in humans or other animals.
The Acoustical Society of America provides an important scientific home for researchers pursuing questions related to sound and hearing. This group has positively shaped many of our careers, especially by providing access to an incredible group of mentors and role models. Receiving an award created by Bill and Christine Hartmann, two of my own role models, is truly a great honor. This award presents a challenge for me to emulate their life of discovery, presentation, publication, service, and education throughout the world, said Carney.
The goal of Dr. Carney's research program is to understand how the brain hears. The initial response of brain cells to sound is a complicated pattern of electrical pulses, a pattern that is modified and interpreted by millions of cells in many parts of the brain. Studies of physiology, human hearing, and computer models are combined to understand how this process works in listeners with normal hearing, so that an answer can be found to the question: How is the brain so good at hearing in noisy environments? Another goal is to understand why only relatively small amounts of hearing loss cause significant problems. Why does background noise (such as that in a busy restaurant) become so problematic for people with hearing loss? Answers to both of these questions will lead to better strategies for aiding listeners with hearing loss.
For more information, visit the Department of Biomedical Engineering story.
June 9, 2015
John J. Foxe, Ph.D., a nationally-regarded scientist in the field of neurobiology, has been named the research director of the DelMonte Neuromedicine Institute (DNI) and the Kilian J. and Caroline F. Schmitt Chair of the Department of Neurobiology and Anatomy at the University of Rochester School of Medicine and Dentistry.
The University of Rochester has long been home to some of the nation's most innovative and groundbreaking research in the field of neuroscience and neuromedicine,said Joel Seligman, president of the University of Rochester.
John's appointment signals our determination to make this field a centerpiece of our progress as a University and Medical Center.
I am honored to be taking the helm of the DNI at this incredibly exciting time in modern neuroscience research,said Foxe.
The University of Rochester is already world-renowned for its superb work in this field and we now have the opportunity to build an even stronger presence. Tens of millions of Americans suffer from a major mental illness each year, be it depression or anxiety, a major psychotic disorder, or Alzheimer's disease, stroke, or addiction. And the list goes on. The National Institutes of Health estimates that only about half of these people ever receive treatment. We can and we must do better. It is only through research that we can develop new effective treatments and I am committed to placing the DNI and the University of Rochester at the very forefront of these efforts.
June 4, 2015
Suzanne Haber, Ph.D.
Suzanne Haber leads a research team to investigate OCD. She says the disease is characterized by intrusive, ruminating thoughts (obsessions), and impulses to carry out repetitive behaviors (compulsions), despite the awareness by most patients that these behaviors don't make sense.
The goal of a new $10 million grant awarded to the scientists is to improve our understanding of the brain networks that play a central role in obsessive-compulsive disorder (OCD). Together with leading mental health researchers at four other institutions in the U.S., they will pinpoint specific abnormalities within the brain circuits that are associated with the disease and use this information to guide new treatment options for the three million-plus Americans who live with the disorder.
The five-year grant from the National Institute of Mental Health (NIMH) establishes a new Silvio O. Conte Center for Basic and Translational Mental Health Research at the University of Rochester. Conte Centers are designed to bring scientists with diverse but complimentary backgrounds together to improve the diagnosis and treatment of mental health disorders.
For more information, please visit the URMC newsroom article.
May 11, 2015
Ben Crane Awarded Nicholas Torok Vestibular Award by the American Neurotology Society
Otolaryngology associate professor, Benjamin Crane, MD, PhD, was awarded the Nicholas Torok Vestibular Award by the American Neurotology Society at the 50th Annual meeting in Boston on April 25th. The title of his presentation was
An automated vestibular rehabilitation method for unilateral vestibular hypofunction.
The $1500 award is offered by the Society for the best lecture on an innovative observation, experience or technique in the field of Vestibular Basic Science, i.e., physiology, pathology or subjects serving clinical progress.
March 10, 2015
Congratulations to Nguyen Mai
Nguyen Mai, MD/PhD student
Congrats to Nguyen Mai, MD/PhD student, in Dr. Marc Halterman's lab for receiving an individual fellowship F30 from NIH's National Institute of Neurological Disorders and Stroke for her work on
Role of lung-brain coupling on neutrophil priming and reperfusion injury following global cerebral ischemia.
March 10, 2015
VasoMark advances to the next phase!
A group of students from Neuroscience Graduate Program and Neurosurgery Residency Program have teamed up to compete in the National Institutes of Health
Neuro Startup Challenge. This new effort offers pre- and post-doctoral students from biomedical, legal, and business backgrounds the opportunity to compete for licenses to patented technologies from the NIH portfolio.
The teams model a business around the intellectual property, and seek startup funding from partnering angel investor and venture capitalist firms in order to bring the proposed technology to the biomedical marketplace. The NGP and Neurosurgery team, named VasoMark, selected two patents for the development of a minimally invasive diagnostic for the detection of primary and recurrent malignant brain tumors. VasoMark successfully completed Phase I of the competition, where they developed a two-minute elevator pitch and executive summary describing their intended entrepreneurial use of the selected technology. They are currently developing a business plan and live investor pitch describing their business model, intended market, and future areas of expansion for their selected patents.
February 13, 2015
At upper left, a healthy astrocyte (a supportive brain cell) is shown in blue between green sheaths of myelin, which are produced by oligodendrocytes, the tentacled objects also seen in green.In individuals suffering from Progressive multifocal leukoencephalopathy, JC viruses (red particles) first infect the astrocyte (upper right) and mutate, eventually causing the astrocyte to explode (bottom image). The viruses then infect the oligodendrocytes.
When University researchers Steven Goldman and Maiken Nedergaard created a mouse model whose brains consisted of both animal neurons and human glia cells, their study initially focused on findings that the human cells essentially made the mice smarter.
However, they also created a powerful new platform for researchers to study human glial cells in experimental animals. And that is providing new insights into Progressive multifocal leukoencephalopathy (PML).
The study, out today in the journal Cell Stem Cell, suggests that the evolution of a subset of glia called astrocytes – which are larger and more complex in humans than other species – may have been one of the key events that led to the higher cognitive functions that distinguish us from other species.
For more information please visit the URMC Newsroom article.
February 4, 2015
NBA Faculty Candidate: Krishnan Padmanabhan, PhD
Krishnan Padmanabhan, PhD
Faculty candidate Dr. Padmanabhan, Junior Fellow Crick-Jacobs Center for Theoretical and Computational Biolgy The Salk Institute of Biological Studies, will present the talk
The Role of Diversity in the Neural ComputationsMonday, February 23rd at 2:00pm in K-307 (3-6408)
A key question in neuroscience is to understand how neuronal circuits process sensory information and generate behaviors in response to that information. Consider the sense of smell for instance. In a single sniff, mammals can synthesize data about dozens of volitile chemical compounds to create a singular unified perception, like the smell of coffee. In the olfactory system of mice, feedforward projections from the principle cells of the main olfactory bulb relay information about these odors directly to cortical regions as an early step toward forming a sensory percept. Feedback projections from these cortical areas back to early olfactory structures dynamically impact the way incoming odor information is processed based on such features as experience, memory and brain state. How these two computations are done, and how the olfactory system uses these computations to generate behavior remain open questions.
In my talk, I will discuss our recent work tackling 2 aspects of this process.
- How the biophysical properties of neurons improves information transmission in the feedforward direction.
- How the anatomy of connections from the higher processing areas may reveal key computational principles about sensory processing.
February 1, 2015
MSTP Announces 40th Anniversary Celebration!
The Medical Scientist Training Program (MSTP) is excited to announce a celebration of the 40th anniversary of the MSTP NIH training grant on Friday, October 9, 2015.
The keynote speaker will be an MSTP alumni from the Class of 1980: Edward Rubin, MD, PhD, Director, DOE Joint Genome Institute.
EddyRubin is an internationally-known geneticist and medical researcher at the Lawrence Berkeley National Laboratory in Berkeley, California, where he became head of the Genomic Sciences Division in 1998. In 2002 he assumed the directorship of the DOE Joint Genome Institute (JGI) to lead the JGI ’s involvement in the Human Genome Project (HGP).
For more information and schedule of events for the day, please visit the MSTP 40th Anniversary page.
January 12, 2015
NIH Neuro Start Up Challenge
Several neuroscience graduate students and clinicians from the University of Rochester are involved in the NIH Neuro Start Up Challenge and have developed their elevator pitch and executive summary as part of the public voting phase. We encourage the neuroscience community to visit their Showcase page and provide votes and constructive feedback on the discussion board this week. Public voting will run Monday, January 12th through Friday, January 16th.
Team: University of Rochester- 8&9.A (Inventions 8 and 9)
Company Name: VasoMark
About the Challenge: The Neuro Start Up Challenge, launched by the NIH in partnership with the CAI and HPN, is designed to bring brain-related, patented technologies from the NIH to market. Teams of medical, scientific and business experts compete in several phases to create a company and execute a business plan with the ultimate goal of launching their start-up.
Thank you for your support