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Currently Enrolling Clinical Trials

Spine Surgery Pain

Gralise for Spine Surgery Pain (GRASSP)- A partially enriched, placebo controlled, randomized, double-blind cross over trial of Gralise for the treatment of post laminectomy pain syndrome.

For more information visit: open-studies or contact translational pain research at (585) 340-8926

Completed Clinical Trials

Failed Back Surgery Syndrome

A prospective randomized study of multicolumn implantable lead stimulation for predominant low back pain.

Painful Diabetic Neuropathy

Evaluation of the impact of subject and staff training on the pregabalin vs. placebo difference in subjects with painful diabetic neuropathy (PDN).

Chronic Low Back Pain & Opioid Induced Constipation

A Randomized, Double-blind, Double-dummy, Placebo-controlled, Active-controlled, Parallel-group, Multicenter Trial of Oxycodone/Naloxone controlled-release Tablets (OXN) to Assess the Analgesic Efficacy (Compared to Placebo) and the Management of Opioid-induced Constipation (Compared to Oxycodone Controlled-release Tablets (OXY)) in Opioid-experienced Subjects with Moderate to Severe Chronic Low Back Pain and a History of Opioid-induced Constipation who Require Around-the-clock Opioid Therapy.

Chronic Low Back Pain in Opioid Experienced & Opioid Naive Subjects

A Phase 3, Multi-Center, Randomized, Double-blind, Placebo-Controlled, Safety, Tolerability, and Efficacy Study of Oxycodone DETERx™ Versus Placebo in Opioid-Experienced and Opioid-Naive Subjects with Moderate-to-Severe Chronic Low Back Pain.

Post-Traumatic Peripheral Neuropathic Pain

A randomized double blind placebo controlled parallel Group study of the efficacy and safety of pregabalin (bid) in Subjects with post-traumatic peripheral neuropathic pain.

Opioid-induced Bowel Dysfunction Pivotal Assessment of Lubiprostone (OPAL)

A Multicenter, Randomized, Placebo-controlled, Double-blinded Study of the Efficacy and Safety of Lubiprostone in Subjects With Opioid-induced Bowel Dysfunction (OBD). The primary purpose of the study is to evaluate the efficacy and safety of lubiprostone administration in subjects with OBD.

PHN & PTN Study

A Multicenter, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42160443 in Subjects With Postherpetic Neuralgia and Post-traumatic Neuralgia, Followed by a Double Blind Safety Extension and an Open-label Safety Extension.

Lumbar Stenosis Study I

Lumbar Stenosis Outcomes Research (LUSTOR I): A randomized, Single-Site, Two-Period, Placebo-Controlled Crossover Trial Comparing Pregabalin With Placebo for the Treatment of Intermittent Neurogenic Claudication Associated With Lumbar Spinal Stenosis.

Lumbar Stenosis Study II

Lumbar Stenosis Outcomes Research (LUSTOR II): Opana IR Versus Placebo and Active Control for the Treatment of Walking Impairment in Lumbar Spinal Stenosis: A Double-Blind Randomized, Cross-Over Trial.