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Transfusion Medicine

Clinical Service

Department Investigators

Neil Blumberg Blood transfusion immunology, clinical outcomes research
Scott A. Kirkley Blood transfusion immunology
Majed Refaai Hemostasis and thrombosis
Amy Schmidt  
Sherry Spinelli Platelets as mediators of inflammation

Current Awards

Neil Blumberg 
(site PI)
ABC-PICU randomized trial of longer vs. shorter storage of red cells
Neil Blumberg 
(consultant)
Eliminating mediators of toxicity from stored blood
Neil Blumberg 
(co-investigator)
Effect of cigarette smoke exposure and smoking cessation on vascular cell biology
Majed Refaai Clinical performance of the Investigational Hemochron MCS 7000 Whole Blood Coagulation System
Majed Refaai 
(co-investigator)
Evaluation of the ACCU-CHEK Inform II system in critically ill neonatal and pediatric patients
Majed Refaai External evaluation of Heparin and triferic drug interaction
Majed Refaai Transfusion of INTERCEPT platelet components
Majed Refaai Efficacy and safety of caplacizumab in patients with acquired TTP 
Majed Refaai Efficacy and safety of caplacizumab in patients with acquired TTP (prospective follow-up study)
Majed Refaai Study of Andexanet Alfa in patients receiving a Factor XA inhibitor who have acute major bleeding
Majed Refaai Treatment of Polycythemia Vera in United States clinical practices
Majed Refaai 
(co-investigator)
Romidepsin in HIV-infected adults with suppressed anemia on antitroviral therapy (clinical trial, AIDAS)
Majed Refaai 
(co-investigator)
(NIH) Leukapheresis of HIV patients and analyzing CD4+ and CD8+ T cells
Majed Refaai 
(co-investigator)
Plasma exchange to reduce anti-ABO IgG antibodies in kidney recipients
Sherry Spinelli Effect of cigarette smoke exposure and smoking cessation on vascular cell biology

Interdepartmental Collaborations

Environmental Medicine

Richard Phipps Immunobiology

University of Michigan

Mary Rogers Epidemiologic studies of blood transfusion utilization and clinical outcomes

Medicine: Hematology/Oncology

Charles Francis Hemostasis & response to injury

Pediatrics-Pulmonary and Intensive Care Medicine

Jill Cholette Transfusion immunology and clinical outcomes in pediatric cardiac surgery

Anesthesiology

Laurent Glance Transfusion practice and clinical outcomes in non-cardiac surgery

University of Houston, Texas

Sergey Shevkoplyas  Eliminating mediators of toxicity from stored blood

French National Blood Service

Olivier Garraud  Platelet biology

Medicine: Pulmonary/Critical Care

Anthony Pietropaoli  Biologic mediators of poor clinical outcome after red cell transfusions

Wilmot Cancer Institute (Medicine: Hematology/Oncology)

Jane Liesveld Transfusion practice and clinical outcomes in acute leukemia & stem cell transplant
Jason Mendler Transfusion practice and clinical outcomes in acute leukemia and stem cell transplant

 

Clinical Highlights

  • Laboratory directors: Neil Blumberg, Scott Kirkley, Majed Refaai, Amy Schmidt
  • Includes transfusion service, autologous donation program, stem cell processing laboratory, aphaerisis program, coagulation/hemostasis laboratory consultation service, immunohematology reference laboratory, and patient blood management program.
  • Provides washed transfusions to younger patients with acute leukemia based upon local data demonstrating improved short and long term survival.
  • Transfuses only blood components that are ABO identical to the patient, leukocyte reduced and irradiated.
  • Stem cell laboratory processes and stores peripheral stem cells and bone marrow products in preparation for transplant.