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Faculty Research Interests

Francis Gigliotti, M.D., Chief

  • Pneumocystis carinii pneumonia
  • Infections in the immunocompromised host
  • Inflammatory lung injury
  • Opportunistic infections

Samir Bhagwat, Ph.D.

  • Monoclonal antibodies for the study of P. carinii
  • Lung damage from P. carinii: pathogenesis and prevention
  • Chemokine regulation of immune cell recruitment during Pneumocystis pneumonia

Mary T. Caserta, M.D.

  • Viral respiratory infections in children
  • Effects of psychosocial factors on susceptibility to infectious diseases
  • Epidemiology and clinical consequences of infection with human herpesvirus-6 and herpesvirus-7 in children with special emphasis on epidemiology and pathogenesis

Cynthia Christy, M.D.

  • Improving medical education especially relating to professionalism issues.

Damian J. Krysan, M.D., Ph.D.

  • Antifungal and antibiotic drug discovery
  • Fungal pathogenesis

Jennifer Nayak, M.D.

  • Understanding how a child's early exposure to influenza shapes immunity and poises the immune system to respond to subsequent influenza challenge
  • Utilizing CD4 T cell-mediated immunity to improve vaccines directed against pandemic strains of influenza
  • Understanding how pre-existing CD4 T cells directed against influenza influence the ability of B cells to respond to influenza vaccination

Jing Wang, Ph.D.

  • Macrophage mediated fungal clearance and lung injury during Pneumocystis pneumonia
  • Mechanism of immune mediated lung injury during infectious diseases
  • Seeking new strategies to treat inflammatory lung diseases

Geoffrey A. Weinberg, M.D.

  • Integration of vaccine-preventable enteric and respiratory disease epidemiologic and laboratory surveillance  with research on the improvement of vaccine delivery and efficacy (New Vaccine Surveillance Network, funded by CDC contract);
  • Clinical trials of new pharmaceuticals, biologics, and vaccines in children and pregnant women infected with HIV (International Maternal, Pediatric, and Adolescent Clinical Trials Network, funded by NIH/NICHD contract).

Melanie Wellington, M.D., Ph.D.

  • Host defense against infection with Candida
  • Fungal pathogenesis
  • Programmed cell death pathways in the immune response to fungi

Terry W. Wright, Ph.D.

  • Role of alveolar epithelial cells in respiratory pathogen detection
  • Modulation of T cell immune responses as adjunctive therapy for PcP
  • Macrophage phenotype: modulation of inflammation and host defense