Clinical Trials, Health Services & Prevention

Research Project Areas

The University of Rochester is the lead site in a joint Rochester-Buffalo Center in the National Institute of Child Health and Human Development’s Neonatal Research Network . The Network is a collaborative group of 15 centers performing neonatal clinical trials and observational research. Current research endeavors include:

• The Budesonide in Babies (BiB) Trial
• Randomized Controlled Trial of Cycled Phototherapy
• Trial to Improve Red Cell Mass and Neuroprotection in Preterm Infants
• Neurodevelopmental Effects of Donor Human Milk vs. Preterm Formula in ELBW infants
• Milrinone in Congenital Diaphragmatic Hernia
• Moderately Preterm Infants with Caffeine at Home for Apnea Trial
• Management of the PDA Trial
• A Randomized Trial of Targeted Temperature Management With Whole Body Hypothermia For Moderate And Severe Hypoxic-Ischemic Encephalopathy In Premature Infants 33-35 Weeks Gestational Age
• Survey of Morbidity and Mortality in Very Low Birth Weight (VLBW) Infants
• Follow-Up of Infants Born Less Than or Equal to 26 Completed Weeks Gestational Age at 22-26 Months Corrected Age
• Follow-up of infants enrolled in the Hydrocortisone for BPD Trial at 5-6 years corrected age to assess functional developmental and respiratory outcomes at early school age
• Follow-up of infants enrolled in the TOP Trial at 5-6 years corrected age to assess neurological and functional outcomes at early school age based on neonatal transfusion threshold

Other research includes:

• High fidelity simulation technology for team training
• Telehealth simulation for training for neonatal emergencies
• Trial of Eat/Sleep/Console approach to neonatal opioid withdrawal syndrome
• Neonatal hemodynamic measurements and risk for acute kidney injury (put in kidney section, as well)
• Measurement of chest excursion during high frequency ventilation (put in lung section, as well)

Investigators

• Melissa Carmen, M.D.
• Patricia R. Chess, M.D., M.S.
• Rita Dadiz, D.O.
• Carl T. D’Angio, M.D., Chief
• Ronnie Guillet, M.D., Ph.D.
• Irina Prelipcean, M.D., F.A.A.P.
• Julie E. Riccio, M.D.
• Timothy P. Stevens, M.D., M.P.H.