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Nina F. Schor, M.D., Ph.D.

Nina F. Schor, M.D., Ph.D.

About Me

Certified Specialties

Neurology with Special Qualification in Child Neurology - American Board of Psychiatry & Neurology

Pediatrics - American Board of Pediatrics

Faculty Appointments

Professor (Part-Time) - Department of Pediatrics (SMD)

Credentials

Post-doctoral Training & Residency

Chief Resident & Clinical Fellow in Neurology, Children's Hospital and Harvard Medical School, Boston, MA 1985 - 1986

Resident & Clinical Fellow in Neurology, Longwood Area Program, Harvard Medical School, Boston, MA 1983 - 1985

Resident & Clinical Fellow in Pediatrics, Children's Hospital and Harvard Medical School, Boston, MA 1982 - 1983

Intern & Clinical Fellow in Pediatrics, Children's Hospital and Harvard Medical School, Boston, MA 1981 - 1982

Education

MD | Cornell University Medical School. Medicine. 1981

PhD | Rockefeller University. Medical Biochemistry. 1980

BS | Yale University. Molecular Biophysics Biochemistry. 1975

Awards

National Research Mentoring Network Master Mentor. 2017

Keynote Speaker/Panel Member, Tri-Institutional MD-PhD Program 40th Anniversary Student Retreat. 2012

Fellow. 2012

Annual Pediatric Neurology Invited Lecturer. 2010

Keynote Speaker, University of Utah Neurology Retreat. 2010

Baldwin Lecturer. 2009

Dean's Distinguished Lecturer. 2008

E. Stanley Emery Professor. 2008

William H. Eilinger Endowed Chair of Pediatrics. 2007

Keynote Speaker. 2006

Distinguished Neurology Teacher Award. 2005

Best Doctors in America. 2004 - 2006

Distinguished Alumni Speaker Series Speaker. 2004

Distinguished Alumni Speaker. 2004

Named to Best Doctors in America. 2002

Craumer Endowed Professorship for Pediatrics Research. 2000

Volunteer in the Schools Award. 1999

Named to Best Doctors in America. 1999

Teaching Excellence Award, Second Year Medical School Class. 1997

Chancellor's Distinguished Teaching Award. 1996

Kenneth E. Schuitt-Dean's Master Educator Award. 1995

Conferral of tenure. 1991

Presidential Citation. 1991

Benjamin N. Cardozo High School Women in Science Award. 1990

Michael E. Miller Young Investigator Award. 1990

Child Neurology Fellows' Award for Excellence in Teaching. 1987 - 1989

Ruth Estrin Goldberg Memorial Award for Cancer Research. 1985

Alfred A. Richman Award for Cardiopulmonary Research. 1980

Cold Spring Harbor Laboratory Undergraduate Research Participant. 1973

Westinghouse Science Talent Search, First Prize. 1972

Yale National Scholar. 1972

National Merit Scholar. 1972

Tomorrow's Scientists and Engineers Award. 1972

American Academy of Achievement Award. 1972

Research

Dr. Nina F. Schor's research focuses on designing and testing in preclinical models targeted therapy for neuroblastoma, the most common solid tumor of childhood and a derivative of the neural crest. Therapeutic approaches that have been pioneered through her research which include:

(1) adju...
Dr. Nina F. Schor's research focuses on designing and testing in preclinical models targeted therapy for neuroblastoma, the most common solid tumor of childhood and a derivative of the neural crest. Therapeutic approaches that have been pioneered through her research which include:

(1) adjunctive use of 6-hydroxydopamine (tumor cell ablative agent) with TEMPOL (selective normal cell chemoprotectant);

(2) adjunctive use of neocarzinostatin (non-selective chemotherapeutic prodrug) with 6-mercaptodopamine (neural crest-selective activator of neocarzinostatin);

(3) caspase 3-dependent potentiation of apoptosis induced by enediyne chemotherapeutic agents in Bcl-2-overexpressing tumors; and

(4) potentiation of apoptosis induced by chemotherapeutic agents with agonists and antagonists at specific neurotrophin receptors.

In the process of this work, distinct lines of inquiry and drug and mechanism discovery have evolved.

Publications

Journal Articles

The National Institutes of Health Lasker Clinical Research Scholars Program: A Decade of Launching Clinician-Scientist Careers.

Dearolf CR, Lee JS, Pickett CL, Santangelo G, Schor NF

Academic medicine : journal of the Association of American Medical Colleges.. 2024 April 16 Epub 04/16/2024.

The Tangential Dialogue Between Science and Medicine: A Case in Point.

Schor NF

Pediatric neurology.. 2024 January 24153 :96-102. Epub 01/24/2024.

The continuing challenges facing gene-targeted therapies.

Schor NF

Developmental medicine and child neurology.. 2023 April 27 Epub 04/27/2023.

Proceedings of the First Pediatric Coma and Disorders of Consciousness Symposium by the Curing Coma Campaign, Pediatric Neurocritical Care Research Group, and NINDS: Gearing for Success in Coma Advancements for Children and Neonates.

Boerwinkle VL, Schor NF, Slomine BS, Molteni E, Ramirez JM, Rasmussen L, Wyckoff SN, Gonzalez MJ, Gillette K, Schober ME, Wainwright M, Suarez JI

Neurocritical care.. 2023 February 9 Epub 02/09/2023.

Academic Neurology and the COVID-19 Pandemic: Resilience, Hope, and Solutions.

Schor NF, Cudkowicz ME, Banwell B

Neurology.. 2022 December 1 Epub 12/01/2022.

Planning and Implementing Strategically: Year 1 of the NINDS 2021-2026 Strategic Plan.

Schor NF, Scott P, Litvina EY, Torborg C, Kim JL, Zalutsky R, Adams AB

Neurology.. 2022 October 18 Epub 10/18/2022.

The NINDS 2021-2026 Strategic Plan: Partnership and cross-cutting principles.

Schor NF, Scott P, Litvina EY, Torborg C, Kim J, Zalutsky R, Adams AB

Cell.. 2022 April 28185 (9):1445-1448. Epub 1900 01 01.

Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors .

Khazan N, Kim KK, Hansen JN, Singh NA, Moore T, Snyder CWA, Pandita R, Strawderman M, Fujihara M, Takamura Y, Jian Y, Battaglia N, Yano N, Teramoto Y, Arnold LA, Hopson R, Kishor K, Nayak S, Ojha D, Sharon A, Ashton JM, Wang J, Milano MT, Miyamoto H, Linehan DC, Gerber SA, Kawar N, Singh AP, Tabdanov ED, Dokholyan NV, Kakuta H, Jurutka PW, Schor NF, Rowswell-Turner RB, Singh RK, Moore RG

Journal of medicinal chemistry.. 2022 April 11 Epub 04/11/2022.

An Article-Based Format for Medical Specialty and Subspecialty Maintenance of Certification.

Faulkner LR, Juul D, Thomas CR, Anzia JM, Lewis SL, Schor NF, Shen L, Cowan D, Vondrak P

The Journal of continuing education in the health professions.. 2022 February 17 Epub 02/17/2022.

NINDS launches network to develop treatments for ultra-rare neurological diseases.

Schor NF, Tamiz AP, Koroshetz WJ, , Broome AM

Nature biotechnology.. 2021 November 4 Epub 11/04/2021.

Next Generation Strategies for Gene-Targeted Therapies of Central Nervous System Disorders: A Workshop Summary.

Morris JA, Boshoff CH, Schor NF, Wong LM, Gao G, Davidson BL

Molecular therapy : the journal of the American Society of Gene Therapy.. 2021 September 18 Epub 09/18/2021.

Seeking progress in disease modification in Parkinson disease.

Lungu C, Cedarbaum JM, Dawson TM, Dorsey ER, Faraco C, Federoff HJ, Fiske B, Fox R, Goldfine AM, Kieburtz K, Macklin EA, Matthews H, Rafaloff G, Saunders-Pullman R, Schor NF, Schwarzschild MA, Sieber BA, Simuni T, Surmeier DJ, Tamiz A, Werner MH, Wright CB, Wyse R

Parkinsonism & related disorders.. 2021 September 10 Epub 09/10/2021.

Neurodevelopmental Clues to Neurodegeneration.

Schor NF, Bianchi DW

Pediatric neurology.. 2021 August 6123 :67-76. Epub 08/06/2021.

Toward a Smoother Rocky Road.

Schor NF

JAMA neurology.. 2020 October 5 Epub 10/05/2020.

PRMT1 promotes neuroblastoma cell survival through ATF5.

Hua ZY, Hansen JN, He M, Dai SK, Choi Y, Fulton MD, Lloyd SM, Szemes M, Sen J, Ding HF, Angelastro JM, Fei X, Li HP, Wu CR, Yang SY, Malik K, Bao X, George Zheng Y, Liu CM, Schor NF, Li ZJ, Li XG

Oncogenesis.. 2020 May 159 (5):50. Epub 05/15/2020.

Saving neurology: Once more with feeling.

Schor NF, Brashear A

Neurology.. 2019 November 5 Epub 11/05/2019.

Women in medical school leadership positions: Implications for research.

Schor NF

Annals of neurology.. 2019 June 85 (6):789-792. Epub 04/09/2019.

Methylation of DNA and chromatin as a mechanism of oncogenesis and therapeutic target in neuroblastoma.

Ram Kumar RM, Schor NF

Oncotarget.. 2018 April 249 (31):22184-22193. Epub 04/24/2018.

A Life at the Interface: The 2017 Hower Award Lecture.

Schor NF

Pediatric neurology.. 2018 March 80 :3-7. Epub 12/07/2017.

The Decanal Divide: Women in Decanal Roles at U.S. Medical Schools.

Schor NF

Academic medicine : journal of the Association of American Medical Colleges.. 2018 February 93 (2):237-240. Epub 1900 01 01.

Using Chemistry to Target Neuroblastoma.

Hansen JN, Li X, Zheng YG, Lotta LT, Dedhe A, Schor NF

ACS chemical neuroscience.. 2017 October 188 (10):2118-2123. Epub 08/24/2017.

Chance juxtapositions and (un)biased methods in science: More efficient at inefficiency.

Schor NF

Neurology.. 2017 July 1889 (3):218-219. Epub 06/14/2017.

Methylation of the phosphatase-transcription activator EYA1 by protein arginine methyltransferase 1: mechanistic, functional, and structural studies.

Li X, Eberhardt A, Hansen JN, Bohmann D, Li H, Schor NF

FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2017 June 31 (6):2327-2339. Epub 02/17/2017.

Autism today: Have we put the cart before the horse?

Jeste SS, Schor NF

Neurology.. 2017 April 488 (14):1303-1304. Epub 03/08/2017.

The child neurology clinical workforce in 2015: Report of the AAP/CNS Joint Taskforce.

Kang PB, Bale JF, Mintz M, Joshi SM, Gilbert DL, Radabaugh C, Ruch-Ross H,

Neurology.. 2016 September 2787 (13):1384-92. Epub 08/26/2016.

Child neurologists and neurodevelopmental disabilities physicians: "Who-Who Are You?".

Schor NF, Schlaggar BL

Neurology.. 2016 September 2787 (13):1318-9. Epub 08/26/2016.

Protein arginine methyltransferase 1 is a novel regulator of MYCN in neuroblastoma.

Eberhardt A, Hansen JN, Koster J, Lotta LT, Wang S, Livingstone E, Qian K, Valentijn LJ, Zheng YG, Schor NF, Li X

Oncotarget.. 2016 September 277 (39):63629-63639. Epub 1900 01 01.

The Electronic Medical Record and Computerized Physician Order Entry: Challenges and Opportunities for Pediatrics.

Schor NF

The Journal of pediatrics.. 2016 September 176 :5-6. Epub 06/29/2016.

The "neuro" of neuroblastoma: Neuroblastoma as a neurodevelopmental disorder.

Ratner N, Brodeur GM, Dale RC, Schor NF

Annals of neurology.. 2016 July 80 (1):13-23. Epub 04/30/2016.

EYA1 expression and subcellular localization in neuroblastoma and its association with prognostic markers.

Hansen JN, Lotta LT, Eberhardt A, Schor NF, Li X

Journal of cancer research & therapy.. 2016 June 4 (2):11-18. Epub 05/05/2016.

Induction of Expression of p75 Neurotrophin Receptor Intracellular Domain Does Not Induce Expression or Enhance Activity of Mitochondrial Complex II.

Yang YP, Lotta L, Beutner G, Li X, Schor NF

Oxidative medicine and cellular longevity.. 2016 2016 :8752821. Epub 11/10/2015.

Cell Line-Dependent Variability of Coordinate Expression of p75NTR and CRABP1 and Modulation of Effects of Fenretinide on Neuroblastoma Cells.

Yang YP, Wang S, Li X, Schor NF

Oxidative medicine and cellular longevity.. 2016 2016 :7568287. Epub 12/30/2015.

Clinical and ethical judgment: A profound dilemma.

Pullicino PM, Ramos-Estebanez C, Gokhale S, Daly B, Schor NF

Neurology.. 2015 May 584 (18):1910. Epub 1900 01 01.

Author response.

Schor NF

Neurology.. 2015 May 584 (18):1911. Epub 1900 01 01.

Pursuit and achievement of leadership: a view from the top.

Schor NF

Annals of neurology.. 2014 December 76 (6):784-8. Epub 10/31/2014.

Comment: Autonomy vs beneficence.

Schor NF

Neurology.. 2014 October 783 (15):1370. Epub 1900 01 01.

Cerebellar Purkinje cell p75 neurotrophin receptor and autistic behavior.

Lotta LT, Conrad K, Cory-Slechta D, Schor NF

Translational psychiatry.. 2014 July 294 :e416. Epub 07/29/2014.

Abstracts.

Schor NF, Mink J

Annals of neurology.. 2014 July 15 Epub 07/15/2014.

p75 neurotrophin receptor and fenretinide-induced signaling in neuroblastoma.

Ganeshan VR, Schor NF

Cancer chemotherapy and pharmacology.. 2014 February 73 (2):271-9. Epub 11/20/2013.

Kidins220/ARMS is expressed in neuroblastoma tumors and stabilizes neurotrophic signaling in a human neuroblastoma cell line.

Rogers DA, Schor NF

Pediatric research.. 2013 November 74 (5):517-24. Epub 09/02/2013.

Reflections: neurology and the humanities: personal health information in verse.

Schor NF

Neurology.. 2013 October 2281 (17):e123. Epub 1900 01 01.

Introductory address for the John Howland Award recipient, Elizabeth R. McAnarney, MD.

Schor NF

Pediatric research.. 2013 October 74 (4):473-4. Epub 08/07/2013.

Life at the interface: adults with "pediatric" disorders of the nervous system.

Schor NF

Annals of neurology.. 2013 August 74 (2):158-63. Epub 1900 01 01.

Aiming at neuroblastoma and hitting other worthy targets.

Schor NF

Journal of child neurology.. 2013 June 28 (6):768-73. Epub 04/10/2013.

Why our patients (and we) need basic science research.

Schor NF

Neurology.. 2013 May 2880 (22):2070-5. Epub 1900 01 01.

Kidins220/ARMS depletion is associated with the neural-to Schwann-like transition in a human neuroblastoma cell line model.

Rogers DA, Schor NF

Experimental cell research.. 2013 March 10319 (5):660-9. Epub 01/16/2013.

Pediatric neurohospitalists: an idea that has come of age?

Schor NF, Carlson DW

Neurology.. 2013 March 580 (10):880-1. Epub 01/16/2013.

p75NTR: an enhancer of fenretinide toxicity in neuroblastoma.

Ganeshan V, Ashton J, Schor NF

Cancer chemotherapy and pharmacology.. 2013 March 71 (3):777-87. Epub 01/13/2013.

Adult neurology training during child neurology residency.

Schor NF

Neurology.. 2012 August 2179 (8):815-8. Epub 07/11/2012.

Robert J. Joynt, MD, PhD: a tribute.

Schor NF, Mink JW

Journal of child neurology.. 2012 August 27 (8):1077-8. Epub 1900 01 01.

Anticipatory guidance as a principle of faculty development: managing transition and change.

Schor NF, Guillet R, McAnarney ER

Academic medicine : journal of the Association of American Medical Colleges.. 2011 October 86 (10):1235-40. Epub 1900 01 01.

Pharmacologic management of high-risk neuroblastoma in children.

Ganeshan VR, Schor NF

Paediatric drugs.. 2011 August 113 (4):245-55. Epub 1900 01 01.

Pediatric residency preceding child neurology training.

Schor NF

Seminars in pediatric neurology.. 2011 June 18 (2):131-2. Epub 1900 01 01.

Necdin and neurotrophin receptors: interactors of relevance for neuronal resistance to oxidant stress.

Ingraham CA, Wertalik L, Schor NF

Pediatric research.. 2011 April 69 (4):279-84. Epub 1900 01 01.

What the halted phase III ?-secretase inhibitor trial may (or may not) be telling us.

Schor NF

Annals of neurology.. 2011 February 69 (2):237-9. Epub 1900 01 01.

Chopper is prodeath regardless of the effect of p75ICD on sensitivity to oxidative stress.

Qazi A, Halterman MW, Mi Z, Zhang T, Schor NF

Oxidative medicine and cellular longevity.. 2011 2011 :391659. Epub 09/05/2011.

The endoplasmic reticulum stress response factor CHOP-10 protects against hypoxia-induced neuronal death.

Halterman MW, Gill M, Dejesus C, Ogihara M, Schor NF, Federoff HJ

The Journal of biological chemistry.. 2010 July 9285 (28):21329-40. Epub 05/06/2010.

Differential roles of Trk and p75 neurotrophin receptors in tumorigenesis and chemoresistance ex vivo and in vivo.

Bassili M, Birman E, Schor NF, Saragovi HU

Cancer chemotherapy and pharmacology.. 2010 May 65 (6):1047-56. Epub 08/22/2009.

The child is father to the man: developmental roles for proteins of importance for neurodegenerative disease.

Rogers D, Schor NF

Annals of neurology.. 2010 February 67 (2):151-8. Epub 1900 01 01.

Reflections: neurology and the humanities. Prayer (dement me not).

Schor NF

Neurology.. 2010 January 1274 (2):179. Epub 1900 01 01.

Necdin and TrkA contribute to modulation by p75NTR of resistance to oxidant stress.

Ingraham CA, Schor NF

Experimental cell research.. 2009 December 10315 (20):3532-42. Epub 10/08/2009.

p75NTR-dependent modulation of cellular handling of reactive oxygen species.

Mi Z, Rogers DA, Mirnics ZK, Schor NF

Journal of neurochemistry.. 2009 July 110 (1):295-306. Epub 04/30/2009.

New approaches to pharmacotherapy of tumors of the nervous system during childhood and adolescence.

Schor NF

Pharmacology & therapeutics.. 2009 April 122 (1):44-55. Epub 01/23/2009.

In-tube transfection improves the efficiency of gene transfer in primary neuronal cultures.

Halterman MW, Giuliano R, Dejesus C, Schor NF

Journal of neuroscience methods.. 2009 March 15177 (2):348-54. Epub 10/30/2008.

Pharmacotherapy for adults with tumors of the central nervous system.

Schor NF

Pharmacology & therapeutics.. 2009 March 121 (3):253-64. Epub 11/27/2008.

Role of tyrosine phosphorylation in the antioxidant effects of the p75 neurotrophin receptor.

Zhang T, Mi Z, Schor NF

Oxidative medicine and cellular longevity.. 2009 2 (4):238-46. Epub 1900 01 01.

Reflections: neurology and the humanities. Developmental arrest.

Schor NF

Neurology.. 2008 September 2371 (13):1038. Epub 1900 01 01.

Molecular predictors of human nervous system cancer responsiveness to enediyne chemotherapy.

Rogers D, Nylander KD, Mi Z, Hu T, Schor NF

Cancer chemotherapy and pharmacology.. 2008 September 62 (4):699-706. Epub 03/13/2008.

Resident work hours: isolating one ledger column and missing the point.

Schor NF

Neurology.. 2008 July 2971 (5):374. Epub 1900 01 01.

Loss of c/EBP-beta activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons.

Halterman MW, De Jesus C, Rempe DA, Schor NF, Federoff HJ

Molecular and cellular neurosciences.. 2008 June 38 (2):125-37. Epub 02/13/2008.

Expression and p75 neurotrophin receptor dependence of cholesterol synthetic enzymes in adult mouse brain.

Korade Z, Mi Z, Portugal C, Schor NF

Neurobiology of aging.. 2007 October 28 (10):1522-31. Epub 08/02/2006.

p75NTR enhances PC12 cell tumor growth by a non-receptor mechanism involving downregulation of cyclin D2.

Fritz MD, Mirnics ZK, Nylander KD, Schor NF

Experimental cell research.. 2006 October 15312 (17):3287-97. Epub 06/28/2006.

Bcl-2 overexpression disrupts the morphology of PC12 cells through reduced ERK activation.

Mi Z, Mirnics ZK, Schor NF

Brain research.. 2006 September 271112 (1):46-55. Epub 08/17/2006.

Oxidation and cytotoxicity of 6-OHDA are mediated by reactive intermediates of COX-2 overexpressed in PC12 cells.

Tyurina YY, Kapralov AA, Jiang J, Borisenko GG, Potapovich AI, Sorokin A, Kochanek PM, Graham SH, Schor NF, Kagan VE

Brain research.. 2006 June 61093 (1):71-82. Epub 05/18/2006.

Child neurology: a trilogy.

Schor NF

Neurology.. 2006 February 2866 (4):613. Epub 1900 01 01.

Brain Mets: a poem in three voices.

Schor NF

Neurology.. 2006 February 1466 (3):457. Epub 1900 01 01.

Bcl-2-mediated potentiation of neocarzinostatin-induced apoptosis: requirement for caspase-3, sulfhydryl groups, and cleavable Bcl-2.

Mi Z, Hong B, Mirnics ZK, Tyurina YY, Kagan VE, Liang Y, Schor NF

Cancer chemotherapy and pharmacology.. 2006 February 57 (3):357-67. Epub 07/05/2005.

P75 neurotrophin receptor regulates expression of neural cell adhesion molecule 1.

Mirnics ZK, Yan C, Portugal C, Kim TW, Saragovi HU, Sisodia SS, Mirnics K, Schor NF

Neurobiology of disease.. 2005 December 20 (3):969-85. Epub 07/11/2005.

Transcriptome differences between the frontal cortex and hippocampus of wild-type and humanized presenilin-1 transgenic mice.

Unger T, Korade Z, Lazarov O, Terrano D, Schor NF, Sisodia SS, Mirnics K

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.. 2005 December 13 (12):1041-51. Epub 1900 01 01.

Neuroprotective effects of TEMPOL in central and peripheral nervous system models of Parkinson's disease.

Liang Q, Smith AD, Pan S, Tyurin VA, Kagan VE, Hastings TG, Schor NF

Biochemical pharmacology.. 2005 November 170 (9):1371-81. Epub 1900 01 01.

Cholesterol biosynthesis and the pro-apoptotic effects of the p75 nerve growth factor receptor in PC12 pheochromocytoma cells.

Yan C, Mirnics ZK, Portugal CF, Liang Y, Nylander KD, Rudzinski M, Zaccaro C, Saragovi HU, Schor NF

Brain research. Molecular brain research.. 2005 October 3139 (2):225-34. Epub 1900 01 01.

The p75 neurotrophin receptor in human development and disease.

Schor NF

Progress in neurobiology.. 2005 October 77 (3):201-14. Epub 11/16/2005.

The Scholarly Project Initiative: introducing scholarship in medicine through a longitudinal, mentored curricular program.

Schor NF, Troen P, Kanter SL, Levine AS

Academic medicine : journal of the Association of American Medical Colleges.. 2005 September 80 (9):824-31. Epub 1900 01 01.

Treatment with propofol: the new status quo for status epilepticus?

Schor NF, Riviello JJ

Neurology.. 2005 August 2365 (4):506-7. Epub 1900 01 01.

The intracellular domain of p75NTR as a determinant of cellular reducing potential and response to oxidant stress.

Tyurina YY, Nylander KD, Mirnics ZK, Portugal C, Yan C, Zaccaro C, Saragovi HU, Kagan VE, Schor NF

Aging cell.. 2005 August 4 (4):187-96. Epub 1900 01 01.

Presenilin-1-dependent transcriptome changes.

Mirnics K, Korade Z, Arion D, Lazarov O, Unger T, Macioce M, Sabatini M, Terrano D, Douglass KC, Schor NF, Sisodia SS

The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2005 February 925 (6):1571-8. Epub 1900 01 01.

Toward the definition of acute disseminated encephalitis of childhood.

Alper G, Schor NF

Current opinion in pediatrics.. 2004 December 16 (6):637-40. Epub 1900 01 01.

Prevention of catecholaminergic oxidative toxicity by 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl and its recycling complex with polynitroxylated albumin, TEMPOL/PNA.

Weinberg A, Nylander KD, Yan C, Ma L, Hsia CJ, Tyurin VA, Kagan VE, Schor NF

Brain research.. 2004 June 251012 (1-2):13-21. Epub 1900 01 01.

Effects of pH on the cytotoxicity of sodium trioxodinitrate (Angeli's salt).

Stoyanovsky DA, Schor NF, Nylander KD, Salama G

Journal of medicinal chemistry.. 2004 January 147 (1):210-7. Epub 1900 01 01.

Exploiting oxidative stress and signaling in chemotherapy of resistant neoplasms.

Schor NF, Kagan VE, Liang Y, Yan Ch, Tyurina Y, Tyurin V, Nylander KD

Biochemistry. Biokhimii?a?.. 2004 January 69 (1):38-44. Epub 1900 01 01.

Brain imaging and prophylactic therapy in children with migraine: recommendations versus reality.

Schor NF

The Journal of pediatrics.. 2003 December 143 (6):776-9. Epub 1900 01 01.

Early events in Bcl-2-enhanced apoptosis.

Liang Y, Yan C, Nylander KD, Schor NF

Apoptosis : an international journal on programmed cell death.. 2003 December 8 (6):609-16. Epub 1900 01 01.

The supportive academic environment: ingredients for success.

Schor NF

Pediatric neurology.. 2003 November 29 (5):370-3. Epub 1900 01 01.

Formation of nitroxyl and hydroxyl radical in solutions of sodium trioxodinitrate: effects of pH and cytotoxicity.

Ivanova J, Salama G, Clancy RM, Schor NF, Nylander KD, Stoyanovsky DA

The Journal of biological chemistry.. 2003 October 31278 (44):42761-8. Epub 08/14/2003.

DNA microarray profiling of developing PS1-deficient mouse brain reveals complex and coregulated expression changes.

Mirnics ZK, Mirnics K, Terrano D, Lewis DA, Sisodia SS, Schor NF

Molecular psychiatry.. 2003 October 8 (10):863-78. Epub 1900 01 01.

Bcl-2 mediates induction of neural differentiation.

Liang Y, Mirnics ZK, Yan C, Nylander KD, Schor NF

Oncogene.. 2003 August 2122 (35):5515-8. Epub 1900 01 01.

Building a division of child neurology: a tribute to Michael J. Painter, MD.

Schor NF, Crumrine PK

Journal of child neurology.. 2003 February 18 (2):127-30. Epub 1900 01 01.

TrkA as a life and death receptor: receptor dose as a mediator of function.

Yan C, Liang Y, Nylander KD, Schor NF

Cancer research.. 2002 September 162 (17):4867-75. Epub 1900 01 01.

p75-nerve growth factor as an antiapoptotic complex: independence versus cooperativity in protection from enediyne chemotherapeutic agents.

Yan C, Liang Y, Nylander KD, Wong J, Rudavsky RM, Saragovi HU, Schor NF

Molecular pharmacology.. 2002 April 61 (4):710-9. Epub 1900 01 01.

Role of caspase 3-dependent Bcl-2 cleavage in potentiation of apoptosis by Bcl-2.

Liang Y, Nylander KD, Yan C, Schor NF

Molecular pharmacology.. 2002 January 61 (1):142-9. Epub 1900 01 01.

Phosphatidylserine peroxidation during apoptosis. A signaling pathway for phagocyte clearance.

Tyurina YY, Tyurin VA, Liu SX, Smith CA, Shvedova AA, Schor NF, Kagan VE

Sub-cellular biochemistry.. 2002 36 :79-96. Epub 1900 01 01.

Signal transduction for clinicians: why should we care?

Schor NF

Pediatric neurology.. 2001 November 25 (5):361-7. Epub 1900 01 01.

Apoptosis in the absence of caspase 3.

Liang Y, Yan C, Schor NF

Oncogene.. 2001 October 420 (45):6570-8. Epub 1900 01 01.

Phospholipid signaling in apoptosis: peroxidation and externalization of phosphatidylserine.

Tyurina YY, Shvedova AA, Kawai K, Tyurin VA, Kommineni C, Quinn PJ, Schor NF, Fabisiak JP, Kagan VE

Toxicology.. 2000 August 7148 (2-3):93-101. Epub 1900 01 01.

Oxidative signaling pathway for externalization of plasma membrane phosphatidylserine during apoptosis.

Kagan VE, Fabisiak JP, Shvedova AA, Tyurina YY, Tyurin VA, Schor NF, Kawai K

FEBS letters.. 2000 July 14477 (1-2):1-7. Epub 1900 01 01.

Neurology of systemic autoimmune disorders: a pediatric perspective.

Schor NF

Seminars in pediatric neurology.. 2000 June 7 (2):108-17. Epub 1900 01 01.

Interaction between 6-hydroxydopamine and transferrin: "Let my iron go".

Borisenko GG, Kagan VE, Hsia CJ, Schor NF

Biochemistry.. 2000 March 2839 (12):3392-400. Epub 1900 01 01.

Cell line dependence of Bcl-2-induced alteration of glutathione handling.

Schor NF, Rudin CM, Hartman AR, Thompson CB, Tyurina YY, Kagan VE

Oncogene.. 2000 January 2019 (3):472-6. Epub 1900 01 01.

Differential membrane antioxidant effects of immediate and long-term estradiol treatment of MCF-7 breast cancer cells.

Schor NF, Tyurina YY, Tyurin VA, Kagan VE

Biochemical and biophysical research communications.. 1999 July 5260 (2):410-5. Epub 1900 01 01.

Selective oxidation and externalization of membrane phosphatidylserine: Bcl-2-induced potentiation of the final common pathway for apoptosis.

Schor NF, Tyurina YY, Fabisiak JP, Tyurin VA, Lazo JS, Kagan VE

Brain research.. 1999 June 12831 (1-2):125-30. Epub 1900 01 01.

Neuroblastoma as a neurobiological disease.

Schor NF

Journal of neuro-oncology.. 1999 January 41 (2):159-66. Epub 1900 01 01.

Glutamate-induced cytotoxicity in PC12 pheochromocytoma cells: role of oxidation of phospholipids, glutathione and protein sulfhydryls revealed by bcl-2 transfection.

Tyurin VA, Tyurina YY, Quinn PJ, Schor NF, Balachandran R, Day BW, Kagan VE

Brain research. Molecular brain research.. 1998 October 160 (2):270-81. Epub 1900 01 01.

Whimpers and bangs: of death and dying in the nervous system.

Schor NF

Journal of child neurology.. 1998 July 13 (7):307-12. Epub 1900 01 01.

Effect of inclusion of cost information on student and faculty evaluation of a computer-assisted, problem-based learning course.

Schor NF, Troen P

Academic medicine : journal of the Association of American Medical Colleges.. 1998 May 73 (5):541. Epub 1900 01 01.

The roles of mitotic arrest and protein synthesis in induction of apoptosis and differentiation in neuroblastoma cells in culture.

Smith TK, Nylander KD, Schor NF

Brain research. Developmental brain research.. 1998 February 10105 (2):175-80. Epub 1900 01 01.

Direct evidence for antioxidant effect of Bcl-2 in PC12 rat pheochromocytoma cells.

Tyurina YY, Tyurin VA, Carta G, Quinn PJ, Schor NF, Kagan VE

Archives of biochemistry and biophysics.. 1997 August 15344 (2):413-23. Epub 1900 01 01.

Interrater concordance for faculty grading of student performances in a problem-based learning course.

Schor NF, Troen P, Kanter SL, Janosky JE

Academic medicine : journal of the Association of American Medical Colleges.. 1997 February 72 (2):150-1. Epub 1900 01 01.

Apoptosis in development and disease of the nervous system: II. Apoptosis in childhood neurologic disease.

Gelbard HA, Boustany RM, Schor NF

Pediatric neurology.. 1997 February 16 (2):93-7. Epub 1900 01 01.

Clinical Pediatric Neurology: A Signs and Symptoms Approach

Schor NF.

Neurology. 1997; 49: 314.

Nerve growth factor (NGF)-mediated protection of neural crest cells from antimitotic agent-induced apoptosis: the role of the low-affinity NGF receptor.

Cortazzo MH, Kassis ES, Sproul KA, Schor NF

The Journal of neuroscience : the official journal of the Society for Neuroscience.. 1996 June 1516 (12):3895-9. Epub 1900 01 01.

Adjunctive treatment of murine neuroblastoma with 6-hydroxydopamine and Tempol.

Purpura P, Westman L, Will P, Eidelman A, Kagan VE, Osipov AN, Schor NF

Cancer research.. 1996 May 1556 (10):2336-42. Epub 1900 01 01.

Determinants of the response of neuroblastoma cells to DNA damage: the roles of pre-treatment cell morphology and chemical nature of the damage.

Hartsell TL, Hinman LM, Hamann PR, Schor NF

The Journal of pharmacology and experimental therapeutics.. 1996 May 277 (2):1158-66. Epub 1900 01 01.

Potentiation of enediyne-induced apoptosis and differentiation by Bcl-2.

Cortazzo M, Schor NF

Cancer research.. 1996 March 1556 (6):1199-203. Epub 1900 01 01.

Induction of apoptosis in murine and human neuroblastoma cell lines by the enediyne natural product neocarzinostatin.

Hartsell TL, Yalowich JC, Ritke MK, Martinez AJ, Schor NF

The Journal of pharmacology and experimental therapeutics.. 1995 October 275 (1):479-85. Epub 1900 01 01.

Bobble-head doll syndrome and drop attacks in a child with a cystic choroid plexus papilloma of the third ventricle. Case report.

Pollack IF, Schor NF, Martinez AJ, Towbin R

Journal of neurosurgery.. 1995 October 83 (4):729-32. Epub 1900 01 01.

Integrated case studies and medical decision making: a novel, computer-assisted bridge from the basic sciences to the clinics.

Schor NF, Troen P, Adler S, Williams JG, Kanter SL, Mahling DE, Sorrows B, Skogseid I, Bernier GM

Academic medicine : journal of the Association of American Medical Colleges.. 1995 September 70 (9):814-7. Epub 1900 01 01.

Phenoxyl radicals of etoposide (VP-16) can directly oxidize intracellular thiols: protective versus damaging effects of phenolic antioxidants.

Tyurina YY, Tyurin VA, Yalowich JC, Quinn PJ, Claycamp HG, Schor NF, Pitt BR, Kagan VE

Toxicology and applied pharmacology.. 1995 April 131 (2):277-88. Epub 1900 01 01.

G-protein expression during enediyne-induced neurite outgrowth in neuroblastoma.

Schor NF, Nylander KD, Constantine T, Schwartz MC

Brain research.. 1995 February 27673 (1):175-9. Epub 1900 01 01.

Effects of neocarzinostatin upon the development of tumors from murine neuroblastoma cells.

Will P, Guger KA, Schor NF

Cancer chemotherapy and pharmacology.. 1994 35 (2):115-20. Epub 1900 01 01.

Prevention of neocarzinostatin-induced cell death and morphologic change in SK-N-SH human neuroblastoma cells by continuous exposure to nerve growth factor.

Falcione M, Milligan KD, Schwartz MC, Schor NF

Biochemical pharmacology.. 1993 August 1746 (4):731-8. Epub 1900 01 01.

Neuronal 'differentiation' of murine neuroblastoma cells induced by neocarzinostatin: neural cell adhesion molecules.

Lowengrub JA, Schor NF

Brain research.. 1993 June 4613 (1):123-31. Epub 1900 01 01.

Nervous system dysfunction in children with paraneoplastic syndromes.

Schor NF

Journal of child neurology.. 1992 July 7 (3):253-8. Epub 1900 01 01.

Targeted enhancement of the biological activity of the antineoplastic agent, neocarzinostatin. Studies in murine neuroblastoma cells.

Schor NF

The Journal of clinical investigation.. 1992 March 89 (3):774-81. Epub 1900 01 01.

A neurologist's approach to neuroblastoma.

Schor NF

Journal of child neurology.. 1992 January 7 (1):93-8. Epub 1900 01 01.

(Book review) Advances in Neuroblastoma Research 3

Schor NF.

Pediat Pathol. 1992; 12: 141-142.

Brain glutamine synthetase activity and hyperoxia in neonatal rats.

Schor NF, Ahdab-Barmada M, Nemoto E

Brain research.. 1991 December 6566 (1-2):342-3. Epub 1900 01 01.

Cerebellar glutamine synthetase in children after hypoxia or ischemia.

Dao DN, Ahdab-Barmada M, Schor NF

Stroke.. 1991 October 22 (10):1312-6. Epub 1900 01 01.

Neuroblastoma: a neurochemical approach.

Schor NF

Journal of child neurology.. 1991 July 6 (3):220-8. Epub 1900 01 01.

Inactivation of gamma-glutamylcysteine synthetase by SAPH-3 disulfide: role of the histaminyl moiety.

Schor NF, Cheng B, Siuda JF

Journal of pharmaceutical sciences.. 1991 April 80 (4):311-2. Epub 1900 01 01.

Neocarzinostatin induces neuronal morphology of mouse neuroblastoma in culture.

Schor NF

The Journal of pharmacology and experimental therapeutics.. 1989 June 249 (3):906-10. Epub 1900 01 01.

Inactivation of mammalian brain glutamine synthetase by oxygen radicals.

Schor NF

Brain research.. 1988 July 19456 (1):17-21. Epub 1900 01 01.

Mechanisms of synergistic toxicity of the radioprotective agent, WR2721, and 6-hydroxydopamine.

Schor NF

Biochemical pharmacology.. 1988 May 137 (9):1751-62. Epub 1900 01 01.

Depletion of glutathione by the radioprotective agent S-2-(3-aminopropylamino)ethyl phosphorothioic acid (WR2721).

Schor NF

Biochemical pharmacology.. 1988 February 137 (3):562-3. Epub 1900 01 01.

Adjunctive use of ethiofos (WR-2721) with free radical-generating chemotherapeutic agents in mice: new caveats for therapy.

Tabachnik Schor NF

Cancer research.. 1987 October 1547 (20):5411-4. Epub 1900 01 01.

Association of lupuslike anticoagulant and nonvasculitic cerebral infarction.

Tabachnik-Schor NF, Lipton SA

Archives of neurology.. 1986 August 43 (8):851-2. Epub 1900 01 01.

Protein binding of N-2-mercaptoethyl-1,3-diaminopropane via mixed disulfide formation after oral administration of WR 2721.

Tabachnik NF, Blackburn P, Peterson CM, Cerami A

The Journal of pharmacology and experimental therapeutics.. 1982 February 220 (2):243-6. Epub 1900 01 01.

Biochemical and rheological characterization of sputum mucins from a patient with cystic fibrosis.

Tabachnik NF, Blackburn P, Cerami A

The Journal of biological chemistry.. 1981 July 25256 (14):7161-5. Epub 1900 01 01.

Surgical treatment and the patient with cystic fibrosis.

Tabachnik NF

Surgery, gynecology & obstetrics.. 1981 June 152 (6):837-45. Epub 1900 01 01.

Studies on the reduction of sputum viscosity in cystic fibrosis using an orally absorbed protected thiol.

Tabachnik NF, Peterson CM, Cerami A

The Journal of pharmacology and experimental therapeutics.. 1980 August 214 (2):246-9. Epub 1900 01 01.

Separation of younger red cells with improved survival in vivo: an approach to chronic transfusion therapy.

Piomelli S, Seaman C, Reibman J, Tytun A, Graziano J, Tabachnik N, Corash L

Proceedings of the National Academy of Sciences of the United States of America.. 1978 July 75 (7):3474-8. Epub 1900 01 01.

A second specific endonuclease from Haemophilus aegyptius.

Roberts RJ, Breitmeyer JB, Tabachnik NF, Myers PA

Journal of molecular biology.. 1975 January 591 (1):121-3. Epub 1900 01 01.

Effects of aldehydes on the chlorophyll content of E. gracilis.

Tabachnik NF.

Chemistry. 1973; 46: 25-26.

Levetiracetam for the prophylaxis of migraine headaches in children and adolescents. (Submitted 2006).

Vaisleib II, Neft R, Schor NF.

TBD. .

Books

Pediatric Neurology (2006)

Chapter: Neurological Sequelae of Rheumatologic Disease (in press)

Authors: Schor NF, Sheets R, Szer IS, Ashwal S

Publisher: Mosby 2006

Current Management in Child Neurology (2005)

Chapter: Migraine in Children and Adolescents

Authors: Schor NF

Publisher: BC Decker, Hamilton, Ontario, Canada 2005

Neurology of Neuroblastoma: Neuroblastoma as a Neurobiological Disease (2002)

Authors: Schor NF

Publisher: Kluwer Academic Publishers, Boston, MA 2002

Problem-based Learning: Case Studies, Experience and Practice (2001)

Chapter: No Money Where Your Mouth Is.

Authors: Schor NF

Publisher: Kogan Page, London, UK 2001

Subcellular Biochemistry (2001)

Chapter: Phosphatidylserine peroxidation during apoptosis: a signaling pathway for phagocyte clearance by macrophages

Authors: Tyurina YY, Tyurin VA, Liu SX, Smith CA, Shvedova AA, Schor NF, Kagan VE.

Publisher: Kluwer Academic/Plenum Publishers, New York, NY 2001

Pediatrics: a Problem-based Review (2000)

Chapter: Enlarged abdomen in a 3-month-old boy

Authors: Schor NF

Publisher: WB Saunders Co., Philadelphia, PA 2000

Pediatrics: a Problem-based Review (2000)

Chapter: Jumpiness of feet and eyes in a 4-year-old girl

Authors: Schor NF

Publisher: WB Saunders Co., Philadelphia, PA 2000

Seminars in Pediatric Neurology Series (2000)

Chapter: Neuroimmunology

Authors: Schor NF (editor)

Publisher: WB Saunders Co., Philadelphia, PA 2000

Neuroimmunology. Seminars in Pediatric Neurology Series (2000)

Chapter: Neurological implications of systemic autoimmune disease

Authors: Schor NF

Publisher: WB Saunders Co., Philadelphia, PA 2000

Apoptosis in Neurobiology (1999)

Chapter: Neurooncology and Cancer Therapy

Authors: Schor NF

Publisher: CRC Press, Boca Raton, FL 1999

Current Pediatric Therapy (1998)

Chapter: Neuroblastoma

Authors: Schor NF

Publisher: WB Saunders Co., Philadelphia, PA 1998

Cancer Therapeutics: Experimental and Clinical Agents (1997)

Chapter: The Enediynes

Authors: Schor NF

Publisher: Humana Press Inc., Totowa, NJ 1997