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Jennifer H. Anolik, M.D., Ph.D.

Allergy, Immunology & Rheumatology

Clinical Interests

Lupus; Rheumatology

Contact Information

Phone Numbers

Appointment: (585) 486-0901

Fax: (585) 442-3214

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Research Labs

Her lab focuses on the investigation of B cell tolerance, B cell development and the effects of therapy in lupus, and the development of a murine model of B cell depletion.

Lab: (585) 273-2179

Visit Lab Website

Biography

Dr. Anolik is an adult rheumatologist who practices in the University of Rochester's Lupus Clinic. Her research interests include the role of B cells in the pathophysiology of human systemic lupus and the study of new immuno-modulatory treatments for lupus. As part of the research group at the University of Rochester she has been one of the pioneers in the use of B-cell depletion for the therapy of autoimmune diseases and investigation of the effects of B cell depletion on immune function in SLE patients. She has also pioneered the use of tonsil biopsy as a means of probing immune dysregulation in autoimmune diseases, including SLE and RA.

Research

Dr. Anolik's research interests include the role of B cells in the pathophysiology of human systemic lupus and the study of new immuno-modulatory treatments for lupus. As part of the research group at the University of Rochester she has been one of the pioneers in the use of B-cell depletion for the therapy of autoimmune diseases and investigation of the effects of B cell depletion on immune function in SLE patients. She has also pioneered the use of tonsil biopsy as a means of probing immune dysregulation in autoimmune diseases, including SLE and RA.

Credentials

Faculty Appointments

Specialties

  • Internal Medicine
  • Rheumatology - American Board of Internal Medicine

Education

1988
BA | Swarthmore College
Chemistry

1994
PhD | Univ Rochester Sch Med/Dent
Biochemistry

1996
MD | Univ Rochester Sch Med/Dent
Medicine

Post-doctoral Training & Residency

07/01/1999 - 06/30/2001
Fellowship in Rheumatology at University of Rochester Medical Center

07/01/1997 - 06/30/1999
Residency in Internal Medicine at University of Rochester Medical Center

07/01/1999 - 06/30/2001
Fellowship in Rheumatology at University of Rochester Medical Center

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Awards

2015
American Society for Clinical Investigation

2008
Eisenberg Memorial Lupus Lectureship
Sponsor: University of MO-Columbia
Location: Columbia, MO

2006 - 2008
Lawrence Kohn Senior Teaching Fellow

2005
Edmund Dubois Memorial Lectureship Award
Sponsor: American College of Rheumatology

2003
Buswell Fellowship
Sponsor: University of Rochester Dept of Medicine
Location: Rochester, NY

2001
Rheumatology Fellow Award
Sponsor: American College of Rheumatology

2000 - 2002
NIH Training Grant T32-AI07169-16
Sponsor: University of Rochester
Location: Rochester, NY

1999 - 2000
Stuber Fellowship
Sponsor: University of Rochester
Location: Rochester, NY

1999
Raphael Dolin Resident Research Award
Sponsor: University of Rochester
Location: Rochester, NY

1994 - 1996
Medical Scientist Training Program Scholarship
Sponsor: NIH
Location: University of Rochester

1991 - 1992
Stotz Fellowship
Sponsor: University of Rochester Biochemisty Dept
Location: Rochester, NY

1988 - 1990
Medical Scientist Training Program Scholarship
Sponsor: NIH
Location: University of Rochester

1988 - 1989
Dean's Letter of Recognition
Sponsor: University of Rochester
Location: Rochester, NY

1988
Sigma Xi Scientific Research Society
Location: Swathmore College

1988
Outstanding Senior Chemistry Student Award
Sponsor: American Institutue ofChemists
Location: Swathmore College

1988
Phi Beta Kappa
Location: Swathmore College

1987
Summer Research Fellowship
Sponsor: Dana Foundation
Location: Swathmore College

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Publications

Journal Articles

4/2016
Meednu N, Zhang H, Owen T, Sun W, Wang V, Cistrone C, Rangel-Moreno J, Xing L, Med B, Anolik JH. "Production of RANKL by Memory B Cells: A Link Between B Cells and Bone Erosion in Rheumatoid Arthritis." Arthritis & rheumatology.. 2016 Apr 0; 68(4):805-16.

9/2015
Bird AK, Meednu N, Anolik JH. "New insights into B cell biology in systemic lupus erythematosus and Sjögren's syndrome." Current opinion in rheumatology.. 2015 Sep 0; 27(5):461-7.

2015
Adlowitz DG, Barnard J, Biear JN, Cistrone C, Owen T, Wang W, Palanichamy A, Ezealah E, Campbell D, Wei C, Looney RJ, Sanz I, Anolik JH. "Expansion of Activated Peripheral Blood Memory B Cells in Rheumatoid Arthritis, Impact of B Cell Depletion Therapy, and Biomarkers of Response." PloS one. 2015 10(6):e0128269. Epub 2015 Jun 05.

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Videos

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First New Lupus Drug in 50 Years: What Promise Might it Hold?

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Pop Star Brings Disease to Spotlight