CONTACT INFORMATIONBIOGRAPHYCREDENTIALSAWARDSPUBLICATIONSVIDEOSThomas A. Gasiewicz, Ph.D.Contact InformationPhone NumbersAdministrative: (585) 275-6728LocationsUniversity of Rochester Medical CenterSchool of Medicine and Dentistry601 Elmwood Ave, Box EHSCRochester, NY 14642Additional LinksEnvironmental Health Sciences CenterFaculty AppointmentsProfessor - Department of Environmental Medicine (SMD) BiographyProfessional BackgroundThomas A. Gasiewicz received his B.S. in Chemistry from Canisius College and went on to study Toxicology at the University of Rochester, where he received his PhD in 1977.ResearchReceptor-mediated Modulation of Gene Expression and Association with Biological and Toxic Responses While genetics is known to influence the initiation, progression, and outcome of a variety of human diseases including cancer, it is clear that these are also influenced to a great extent by a number of other factors. These include, for example, exposure to chemicals in the environment, diet and aging. The overall goal of the research in this laboratory is to determine how certain chemicals and substances in the diet influence, in both a positive and negative manner, the processes that influence the progression and outcomes of disease. By understanding the molecular mechanisms by which these factors act, we will also be providing information that can be used in the design of tools for more effective diagnosis and treatment of these diseases.CredentialsEducation1972BS | Canisius CollegeChemistry1977PhD | Univ Rochester Sch Med/DentToxicologyPost-doctoral Training & Residency1977 - 1980National Institutes of Health Postdoctoral Fellow, Center in Toxicology, Department of Biochemistry, Vanderbilt University, Nashville, TNAwards2005Paper of the Year, Immunotoxicology Specialty Section, Society of Toxicology, 20051999Best Paper in Toxicology and Applied Pharmacology, 19981998University of Rochester, School of Medicine, Alumni Award for Excellence in Graduate Education1989 - 1990Visiting Associate Professor, Department of Pharmacology, Stanford University1987 - 1990International Life Sciences Institute Research Foundation Award1977 - 1980National Institutes of Health Postdoctoral Fellowship AwardVIEW ALL expand_morePublicationsJournal Articles2018Bennett JA, Singh KP, Welle SL, Boule LA, Lawrence BP, Gasiewicz TA. "Conditional deletion of Ahr alters gene expression profiles in hematopoietic stem cells." PloS one.. 2018 13(11):e0206407. Epub 2018 Nov 02. 8/2017Zhai W, Sun Y, Jiang M, Wang M, Gasiewicz TA, Zheng J, Chang C. "Differential regulation of LncRNA-SARCC suppresses VHL-mutant RCC cell proliferation yet promotes VHL-normal RCC cell proliferation via modulating androgen receptor/HIF-2?/C-MYC axis under hypoxia." Oncogene.. 2017 Aug 0; 36(31):4525. Epub 2017 Apr 03. 2017Gasiewicz TA, Singh KP, Casado FL. "Aryl Hydrocarbon Receptor and Stem Cells." Stem cells international. 2017 2017:4602854. Epub 2017 Jan 09. VIEW ALL PUBLICATIONSVideosplay_circle_filledTaking On Environmental AgentsClose WindowSchedule an appointment with Thomas A. Gasiewicz, Ph.D.Please answer the following questions to help us find the right appointment for you.Important: If you believe that you have a medical or psychiatric emergency, please call 911 or go to the nearest hospital. This website is not intended for emergency care.Have you seen this provider in the last 2 years?YesNoExisting Patient Schedule or request a follow up appointment online through MyChart. If you do not have a MyChart account, please close this window and call the appointment phone number. Thomas A. Gasiewicz, Ph.D. is currently scheduling for the following appointment type(s): Our policy does not permit patients to establish care with multiple providers within the same practice or specialty without prior approval. If you choose a new provider in the same office, we will cancel the appointment. Please contact the office directly with questions on this policy.