Thomas Edgar Gunter, Ph.D.

Thomas Edgar Gunter, Ph.D.

Contact Information

University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave., Box 712
Rochester, NY 14642

Office: (585) 275-3129
Fax: (585) 275-6007

Journal Articles

Showing all 83 journal articles available.

2013
Martinez-Finley EJ, Gavin CE, Aschner M, Gunter TE. "Manganese neurotoxicity and the role of reactive oxygen species." Free radical biology & medicine. 2013 62:65-75. Epub 2013 Feb 08.
2013
Gunter TE, Gerstner B, Gunter KK, Malecki J, Gelein R, Valentine WM, Aschner M, Yule DI. "Manganese transport via the transferrin mechanism." Neurotoxicology. 2013 34:118-27. Epub 2012 Nov 09.
2010
Gunter TE, Gerstner B, Lester T, Wojtovich AP, Malecki J, Swarts SG, Brookes PS, Gavin CE, Gunter KK. "An analysis of the effects of Mn2+ on oxidative phosphorylation in liver, brain, and heart mitochondria using state 3 oxidation rate assays." Toxicology and applied pharmacology. 2010 249(1):65-75. Epub 2010 Aug 26.
2009
Gunter TE, Sheu SS. "Characteristics and possible functions of mitochondrial Ca(2+) transport mechanisms." Biochimica et biophysica acta. 2009 1787(11):1291-308. Epub 2009 Jan 06.
2009
Gunter TE, Gavin CE, Gunter KK. "The case for manganese interaction with mitochondria." Neurotoxicology. 2009 30(4):727-9. Epub 2009 May 22.
2009
Eliseev RA, Malecki J, Lester T, Zhang Y, Humphrey J, Gunter TE. "Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effect." The Journal of biological chemistry. 2009 284(15):9692-9. Epub 2009 Feb 19.
2009
Vanwinkle BA, de Mesy Bentley KL, Malecki JM, Gunter KK, Evans IM, Elder A, Finkelstein JN, Oberdörster G, Gunter TE. "Nanoparticle (NP) uptake by type I alveolar epithelial cells and their oxidant stress response." Nanotoxicology. 2009 3(4):307-318.
2008
Brookes PS, Parker N, Buckingham JA, Vidal-Puig A, Halestrap AP, Gunter TE, Nicholls DG, Bernardi P, Lemasters JJ, Brand MD. "UCPs--unlikely calcium porters." Nature cell biology. 2008 10(11):1235-7; author reply 1237-40.
2007
Eliseev RA, Filippov G, Velos J, VanWinkle B, Goldman A, Rosier RN, Gunter TE. "Role of cyclophilin D in the resistance of brain mitochondria to the permeability transition." Neurobiology of aging. 2007 28(10):1532-42. Epub 2006 Jul 31.
2006
Gunter TE, Gavin CE, Aschner M, Gunter KK. "Speciation of manganese in cells and mitochondria: a search for the proximal cause of manganese neurotoxicity." Neurotoxicology. 2006 27(5):765-76. Epub 2006 May 07.
2006
Gunter KK, Aschner M, Miller LM, Eliseev R, Salter J, Anderson K, Gunter TE. "Determining the oxidation states of manganese in NT2 cells and cultured astrocytes." Neurobiology of aging. 2006 27(12):1816-26. Epub 2005 Nov 14.
2005
Gunter KK, Aschner M, Miller LM, Eliseev R, Salter J, Anderson K, Hammond S, Gunter TE. "Determining the oxidation states of manganese in PC12 and nerve growth factor-induced PC12 cells." Free radical biology & medicine. 2005 39(2):164-81. Epub 2005 Mar 31.
2004
Eliseev RA, Vanwinkle B, Rosier RN, Gunter TE. "Diazoxide-mediated preconditioning against apoptosis involves activation of cAMP-response element-binding protein (CREB) and NFkappaB." The Journal of biological chemistry. 2004 279(45):46748-54. Epub 2004 Aug 23.
2004
Gunter TE, Yule DI, Gunter KK, Eliseev RA, Salter JD. "Calcium and mitochondria." FEBS letters. 2004 567(1):96-102.
2004
Gunter TE, Miller LM, Gavin CE, Eliseev R, Salter J, Buntinas L, Alexandrov A, Hammond S, Gunter KK. "Determination of the oxidation states of manganese in brain, liver, and heart mitochondria." Journal of neurochemistry. 2004 88(2):266-80.
2003
Eliseev RA, Gunter KK, Gunter TE. "Bcl-2 prevents abnormal mitochondrial proliferation during etoposide-induced apoptosis." Experimental cell research. 2003 289(2):275-81.
2003
Eliseev RA, Salter JD, Gunter KK, Gunter TE. "Bcl-2 and tBid proteins counter-regulate mitochondrial potassium transport." Biochimica et biophysica acta. 2003 1604(1):1-5.
2002
Zuscik MJ, O'Keefe RJ, Gunter TE, Puzas JE, Schwarz EM, Rosier RN. "Parathyroid hormone-related peptide regulation of chick tibial growth plate chondrocyte maturation requires protein kinase A." Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2002 20(5):1079-90.
2002
Zuscik MJ, D'Souza M, Ionescu AM, Gunter KK, Gunter TE, O'Keefe RJ, Schwarz EM, Puzas JE, Rosier RN. "Growth plate chondrocyte maturation is regulated by basal intracellular calcium." Experimental cell research. 2002 276(2):310-9.
2002
Eliseev RA, Gunter KK, Gunter TE. "Bcl-2 sensitive mitochondrial potassium accumulation and swelling in apoptosis." Mitochondrion. 2002 1(4):361-70.
2002
Gunter, K. K.; Miller, L.M.; Aschner, M.; Eliseev, R.; Depuis, D.; Gavin, C. E.; Gunter, T. E.;. "XANES spectroscopy: A Promising tool for toxicology: A tutorial". Neurotox. 2002; 23(3): 127 146. Link
2001
Gunter KK, Gunter TE. "Measurements of intracellular free calcium concentration in biological systems." Current protocols in toxicology. 2001 Chapter 2:Unit 2.5.
2001
Buntinas L, Gunter KK, Sparagna GC, Gunter TE. "The rapid mode of calcium uptake into heart mitochondria (RaM): comparison to RaM in liver mitochondria." Biochimica et biophysica acta. 2001 1504(2-3):248-61.
2001
Gunter TE, Gunter KK. "Uptake of calcium by mitochondria: transport and possible function." IUBMB life. 2001 52(3-5):197-204.
2001
Pfeiffer DR, Gunter TE, Eliseev R, Broekemeier KM, Gunter KK. "Release of Ca2+ from mitochondria via the saturable mechanisms and the permeability transition." IUBMB life. 2001 52(3-5):205-12.
2000
Gunter TE, Buntinas L, Sparagna G, Eliseev R, Gunter K. "Mitochondrial calcium transport: mechanisms and functions." Cell calcium. 2000 28(5-6):285-96.
1999
Gunter, K.K.; Gunter, T. E.;. "Measurements of intracellular free calcium concentration in biological systems". Current Protocols in Toxicology; M. Maines, L.G. Costa, D. J. Reed, S. Sassa, and I. G. Sipes, eds; John Wiley & Sons; New York, New York. 1999; : pp 2.5.1 - 2.5.53. Link
1999
Gavin CE, Gunter KK, Gunter TE. "Manganese and calcium transport in mitochondria: implications for manganese toxicity." Neurotoxicology. 1999 20(2-3):445-53.
1998
Gunter TE, Buntinas L, Sparagna GC, Gunter KK. "The Ca2+ transport mechanisms of mitochondria and Ca2+ uptake from physiological-type Ca2+ transients." Biochimica et biophysica acta. 1998 1366(1-2):5-15.
1998
Reynolds, S. D.; Zuscik, M. J.; Gunter,T. E.; O'Keefe, R. J.; Puzas, J. E.; Rosier , R. N.; Reynolds, P. R. ;. "PTH and PTHrp effects on growth plate chondrocytes: an overview". In: Cells and Materials. 1998; 7(3): 289 - 300. Link
1998
Gunter TE, Buntinas L, Sparagna GC, Gunter KK. "The interaction of mitochondria with pulses of calcium." BioFactors (Oxford, England). 1998 8(3-4):205-7.
1997
Zuscik MJ, Gunter TE, Puzas JE, Rosier RN. "Characterization of voltage-sensitive calcium channels in growth plate chondrocytes." Biochemical and biophysical research communications. 1997 234(2):432-8.
1997
Gavin, C. E.; Gunter, T. E.;. "Manganese dynamics in brain mitochondria". In: Mineral and Metal Neurotoxicology, edited by M. Yasui, K. Ota, M. J. Strong and M. A. Verity. Boca Raton & New York: CRC Press. 1997; : p. 305-310. Link
1995
Sparagna GC, Gunter KK, Sheu SS, Gunter TE. "Mitochondrial calcium uptake from physiological-type pulses of calcium. A description of the rapid uptake mode." The Journal of biological chemistry. 1995 270(46):27510-5.
1995
Li, K.-X.; Williford, D.; Gunter, T.; Sheu, S.-S. ;. "Recurrence of calcium transients in rat cardiomyocytes induced by electrical stimulation in calcium-free Tyrode's solution". Biophys. J. 1995; 68(3): a178. Link
1994
Gunter TE. "Cation transport by mitochondria." Journal of bioenergetics and biomembranes. 1994 26(5):465-9.
1994
Gunter KK, Gunter TE. "Transport of calcium by mitochondria." Journal of bioenergetics and biomembranes. 1994 26(5):471-85.
1994
Zuscik MJ, Gunter TE, Rosier RN, Gunter KK, Puzas JE. "Activation of phosphoinositide metabolism by parathyroid hormone in growth plate chondrocytes." Cell calcium. 1994 16(2):112-22.
1994
Gunter TE, Gunter KK, Sheu SS, Gavin CE. "Mitochondrial calcium transport: physiological and pathological relevance." The American journal of physiology. 1994 267(2 Pt 1):C313-39.
1994
Sparagna GC, Gunter KK, Gunter TE. "A system for producing and monitoring in vitro calcium pulses similar to those observed in vivo." Analytical biochemistry. 1994 219(1):96-103.
1994
Baysal K, Jung DW, Gunter KK, Gunter TE, Brierley GP. "Na(+)-dependent Ca2+ efflux mechanism of heart mitochondria is not a passive Ca2+/2Na+ exchanger." The American journal of physiology. 1994 266(3 Pt 1):C800-8.
1994
Sparagna, G.; Gunter, K. K.; Sheu, S.-S. Gunter, T. E.;. "Can mitochondria sequester pulses from physiological calcium pulses?". In: What is Controlling Life?, edited by E. Gnaiger, F. N. Gellerich and M. Wyss. Innsbruck, Austria: Innsbruck Univ. Press. 1994; : p. 154-158. Link
1994
Zuscik MJ, Puzas JE, Rosier RN, Gunter KK, Gunter TE. "Cyclic-AMP-dependent protein kinase activity is not required by parathyroid hormone to stimulate phosphoinositide signaling in chondrocytes but is required to transduce the hormone's proliferative effect." Archives of biochemistry and biophysics. 1994 315(2):352-61.
1992
Gavin CE, Gunter KK, Gunter TE. "Mn2+ sequestration by mitochondria and inhibition of oxidative phosphorylation." Toxicology and applied pharmacology. 1992 115(1):1-5.
1991
Gunter KK, Zuscik MJ, Gunter TE. "The Na(+)-independent Ca2+ efflux mechanism of liver mitochondria is not a passive Ca2+/2H+ exchanger." The Journal of biological chemistry. 1991 266(32):21640-8.
1991
Gavin CE, Gunter KK, Gunter TE. "Mn2+ transport across biological membranes may be monitored spectroscopically using the Ca2+ indicator dye antipyrylazo III." Analytical biochemistry. 1991 192(1):44-8.
1990
Gunter TE, Zuscik MJ, Puzas JE, Gunter KK, Rosier RN. "Cytosolic free calcium concentrations in avian growth plate chondrocytes." Cell calcium. 1990 11(7):445-57.
1990
Gunter TE, Pfeiffer DR. "Mechanisms by which mitochondria transport calcium." The American journal of physiology. 1990 258(5 Pt 1):C755-86.
1990
Gavin CE, Gunter KK, Gunter TE. "Manganese and calcium efflux kinetics in brain mitochondria. Relevance to manganese toxicity." The Biochemical journal. 1990 266(2):329-34.
1988
Gunter TE, Restrepo D, Gunter KK. "Conversion of esterified fura-2 and indo-1 to Ca2+-sensitive forms by mitochondria." The American journal of physiology. 1988 255(3 Pt 1):C304-10.
1988
Gunter TE, Wingrove DE, Banerjee S, Gunter KK. "Mechanisms of mitochondrial calcium transport." Advances in experimental medicine and biology. 1988 232:1-14.
1986
Wingrove DE, Gunter TE. "Kinetics of mitochondrial calcium transport. II. A kinetic description of the sodium-dependent calcium efflux mechanism of liver mitochondria and inhibition by ruthenium red and by tetraphenylphosphonium." The Journal of biological chemistry. 1986 261(32):15166-71.
1986
Wingrove DE, Gunter TE. "Kinetics of mitochondrial calcium transport. I. Characteristics of the sodium-independent calcium efflux mechanism of liver mitochondria." The Journal of biological chemistry. 1986 261(32):15159-65.
1986
Gunter TE, Jensen BD. "The efficiencies of the component steps of oxidative phosphorylation. I. A simple steady state theory." Archives of biochemistry and biophysics. 1986 248(1):289-304.
1986
Jensen BD, Gunter KK, Gunter TE. "The efficiencies of the component steps of oxidative phosphorylation. II. Experimental determination of the efficiencies in mitochondria and examination of the equivalence of membrane potential and pH gradient in phosphorylation." Archives of biochemistry and biophysics. 1986 248(1):305-23.
1984
Wingrove DE, Amatruda JM, Gunter TE. "Glucagon effects on the membrane potential and calcium uptake rate of rat liver mitochondria." The Journal of biological chemistry. 1984 259(15):9390-4.
1983
Terman BI, Gunter TE. "Characterization of the submandibular gland microsomal calcium transport system." Biochimica et biophysica acta. 1983 730(1):151-60.
1983
Gunter TE, Chace JH, Puskin JS, Gunter KK. "Mechanism of sodium independent calcium efflux from rat liver mitochondria." Biochemistry. 1983 22(26):6341-51.
1982
Gunter KK, Gunter TE, Jarkowski A, Rosier RN. "A method of resuspending small vesicles separated from suspension by protamine aggregation and centrifugation." Analytical biochemistry. 1982 120(1):113-24.
1981
Rosier RN, Tucker DA, Meerdink S, Jain I, Gunter TE. "Ca2+ transport against its electrochemical gradient in cytochrome oxidase vesicles reconstituted with mitochondrial hydrophobic proteins." Archives of biochemistry and biophysics. 1981 210(2):549-64.
1980
Puskin JS, Gunter TE, Coene MT. "On the role of inorganic phosphate in divalent-cation sequestration by mitochondria." European journal of biochemistry. 1980 106(2):425-9.
1980
Rosier RN, Gunter TE. "Calcium uptake by cytochrome oxidase vesicles." FEBS letters. 1980 109(1):99-103.
1979
Rosier RN, Gunter TE, Tucker DA, Gunter KK. "A rapid method for separating small vesicles from suspension." Analytical biochemistry. 1979 96(2):384-90.
1979
Gunter, K. K.; Rosier, R. N.; Tucker, D. A.; Gunter, T. E.;. "Evidence for separate active mitochondrial efflux mechanisms for Ca2+ and Mn2+". In: Calcium Binding Proteins and Cell Function, edited by R.H.Wasserman, R. P. Corradino, E. Carafoli, R. H. Kretsinger, D. H. MacLennan and F. L. Siege. Amsterdam, London, New York: Elsevier/North Holland. 1979; : p. 498-500. Link
1978
Gunter TE, Rosier RN, Tucker DA, Gunter KK. "Uptake of calcium and manganese by rat liver submitochondrial particles." Annals of the New York Academy of Sciences. 1978 307:246-7.
1978
Gunter TE, Gunter KK, Puskin JS, Russell PR. "Efflux of Ca2+ and Mn2+ from rat liver mitochondria." Biochemistry. 1978 17(2):339-45.
1977
Keith AD, Snipes W, Mehlhorn RJ, Gunter T. "Factors restricting diffusion of water-soluble spin labels." Biophysical journal. 1977 19(3):205-18.
1976
Puskin JS, Gunter TE, Gunter KK, Russell PR. "Evidence for more than one Ca2+ transport mechanism in mitochondria." Biochemistry. 1976 15(17):3834-42.
1976
Armbrecht HJ, Gunter TE, Puskin JS, Terepka AR. "An electron paramagnetic resonance study of Mn2+ uptake by the chick chorioallantoic membrane." Biochimica et biophysica acta. 1976 426(3):557-69.
1976
Armbrecht HJ, Terepka AR, Gunter TE. "Energy-dependent Mn2+ and Ca2+ uptake by the embryonic chick chorioallantoic membrane." Biochimica et biophysica acta. 1976 426(3):547-56.
1976
Terepka, A. R.; Coleman, J. R.; Armbrecht, H. J.; Gunter, T. E.;. "Transcellular transport of calcium". Symp. Soc. Exp. Biol. 1976; 30(3): 117-140. Link
1975
Gunter RE, Puskin JS, Russell PR. "Quantitative magnetic resonance studies of manganese uptake by mitochondria." Biophysical journal. 1975 15(4):319-33.
1975
Puskin JS, Gunter TE. "Electron paramagnetic resonance of copper ion and manganese ion complexes with the ionophore A23187." Biochemistry. 1975 14(1):187-91.
1975
Gunter TE, Puskin JS. "The use of electron paramagnetic resonance in studies of free and bound divalent cation: the measurement of membrane potentials in mitochondria." Annals of the New York Academy of Sciences. 1975 264:112-23.
1973
Puskin JS, Gunter TE. "Ion and pH gradients across the transport membrane of mitochondria following Mn ++ uptake in the presence of acetate." Biochemical and biophysical research communications. 1973 51(3):797-803.
1972
Puskin JS, Gunter TE. "Evidence for the transport of manganous ion against an activity gradient by mitochondria." Biochimica et biophysica acta. 1972 275(3):302-7.
1972
Gunter TE, Puskin JS. "Manganous ion as a spin label in studies of mitochondrial uptake of manganese." Biophysical journal. 1972 12(6):625-35.
1972
Gunter TE, Gunter KK. "Pressure dependence of the helix-coil transition temperature for polynucleic acid helices." Biopolymers. 1972 11(3):667-78.
1967
Gunter, T. E.;. "Electron paramagnetic resonance studies of the radiolysis of H2O in the solid state". J. Chem. Phys. 1967; 46(3): 3818-3829. Link
1967
Gunter, T. E.; Jeffries, C. D;. "Proton spin-lattice relaxation in (Nd,La)2Mg3(NO3)12√°24H2O in high fields and low temperatures". Phys. Rev. 1967; 159(3): 290-295. Link
1967
Gunter, T. E.;. "Electron spin resonance of radicals in irradiated hydrogen-oxygen systems in the solid state". In: Solid State Biophysics, edited by S. J. Wyard. New York: McGraw-Hill Book Co. 1967; : p. 157. Link
1966
Gunter, T. E.;. "Paramagnetic resonance of OH radical in solids and proton spin-lattice relaxation at high fields and low temperatures". University of California, Berkeley, Calif. 1966; . Link
1964
GUNTER TE, JEFFRIES CD. "EPR STUDIES ON OH RADICAL IDENTIFICATION IN IRRADIATED H2O. UCRL-11387 SUPPL." UCRL [reports]. 1964 15:8-13.