William Simon, Ph.D.

William Simon, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 712
Rochester, NY 14642

Office: (585) 275-3034
Fax: (585) 275-6007

Journal Articles

Showing all 72 journal articles available.

2016 Jul
Kennedy RB, Simon WL, Gibson MJ, Goergen KM, Grill DE, Oberg AL, Poland GA. "The composition of immune cells serves as a predictor of adaptive immunity in a cohort of 50- to 74-year-old adults." Immunology. 2016 Jul; 148(3):266-75. Epub 2016 May 17.
2013 Jun
Simon W. "Letter to the editor: the RO1 grant bottleneck." Blood cells, molecules & diseases. 2013 Jun; 51(1):1-2. Epub 2013 Feb 20.
2011 Jul 15
Segel GB, Simon W, Lichtman MA. "Should we still be focused on red cell hemoglobin F as the principal explanation for the salutary effect of hydroxyurea in sickle cell disease?" Pediatric blood & cancer. 2011 Jul 15; 57(1):8-9. Epub 2011 Apr 07.
Segel GB; Simon W; Lichtman MA. "Should we still be focused on red cell hemoglobin F as the principal explanation for the salutary effect of hydroxyurea in sickle cell disease?". Pediatric Blood & Cancer. 2011; .
Simon, W. "Should Aspirin be Discontinued at Age 80?". Annals of Internal Medicine. 2009; 150: 396-404. Link
Simon W, Segel GB, Lichtman MA. "Early allogeneic stem cell transplantation for chronic myelogenous leukemia in the imatinib era: a preliminary assessment." Blood cells, molecules & diseases. 2006 37(2):116-24; discussion 125-7. Epub 2006 Aug 10.
Shrager, P.; Simon, W.; Kazarinova-Noyes, K.;. "Na+ Channel Reorganization in Demyelinated Axons. In Multiple Sclerosis as a Neuronal Disease". Edited by Stephen G. Waxman . Elsevier Academic Press. 2005; . Link
2003 Nov 5
Custer AW, Kazarinova-Noyes K, Sakurai T, Xu X, Simon W, Grumet M, Shrager P. "The role of the ankyrin-binding protein NrCAM in node of Ranvier formation." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2003 Nov 5; 23(31):10032-9.
2002 Oct
Weiss B, Clarkson TW, Simon W. "Silent latency periods in methylmercury poisoning and in neurodegenerative disease." Environmental health perspectives. 2002 Oct; 110 Suppl 5:851-4.
1999 Feb
Morsch R, Simon W, Coleman PD. "Neurons may live for decades with neurofibrillary tangles." Journal of neuropathology and experimental neurology. 1999 Feb; 58(2):188-97.
Simon W. "A simple stereoscopic endoscope." JSLS : Journal of the Society of Laparoendoscopic Surgeons. 1998 2(1):67-70.
Maillie, D.H.; Simon, W.;. "A method of estimating the loss of life expectancy from lifetime exposure to low dose rate radiation". Journal of the Franklin Institute. 1995; 332A(3): 93-100. Link
1994 Jun
Maillie HD, Simon W, Greenspan BS, Watts RJ, Quinn BR. "The influence of life table corrections for smokers and nonsmokers on the health effects of radon using the BEIR (biological effects of ioniziing radiation) IV method." Health physics. 1994 Jun; 66(6):615-20.
1993 Jul
Spar IL, Pryor KC, Simon W. "Effect of debt level on the residency preferences of graduating medical students." Academic medicine : journal of the Association of American Medical Colleges. 1993 Jul; 68(7):570-2.
1993 May
Maillie HD, Simon W, Watts RJ, Quinn BR. "Determining person-years of life lost using the BEIR V method." Health physics. 1993 May; 64(5):461-6.
Spar, I.; Simon, W.; Pryor, K.C.;. "The effect of debt level on the residency preferences of graduating medical students". Academic Medicine,. 1993; 68(3): 570-572. Link
1992 Sep
Maillie HD, Baker JV, Simon W, Watts RJ, Quinn BR. "Age related rejoining of broken chromosomes in human leukocytes following X-irradiation." Mechanisms of ageing and development. 1992 Sep; 65(2-3):229-38.
1992 Jul
Forbes GB, Simon W, Amatruda JM. "Is bioimpedance a good predictor of body-composition change?" The American journal of clinical nutrition. 1992 Jul; 56(1):4-6.
1988 Sep
Simon W, Segel GB, Lichtman MA. "Upper and lower time limits in the decision to recommend marrow transplantation for patients with chronic myelogenous leukaemia." British journal of haematology. 1988 Sep; 70(1):31-6.
Simon W. "Anatomy helper: computer-assisted anatomy instruction." Computer methods and programs in biomedicine. 1988 26(1):71-4.
Simon, W;. "Public School Teaching: An Alternative". Science. 1987; : 267. Link
1986 Nov
Segel GB, Simon W, Lichtman MA. "Variables influencing the timing of marrow transplantation in patients with chronic myelogenous leukemia." Blood. 1986 Nov; 68(5):1055-64.
1985 Sep
Coleman PD, Romano J, Lapham L, Simon W. "Cell counts in cerebral cortex of an autistic patient." Journal of autism and developmental disorders. 1985 Sep; 15(3):245-55.
1984 Jul
Segel GB, Simon W, Lichtman MA. "Multicomponent analysis of amino acid transport in human lymphocytes. Diminished L-system transport in chronic leukemic B lymphocytes." The Journal of clinical investigation. 1984 Jul; 74(1):17-24.
1983 Sep
Segel GB, Simon W, Lichtman MA. "A multicomponent analysis of amino acid transport systems in human lymphocytes. 1. Kinetic parameters of the A and L systems and pathways of uptake of naturally occurring amino acids in blood lymphocytes." Journal of cellular physiology. 1983 Sep; 116(3):372-8.
1981 Jul 10
Segel GB, Simon W, Lichtman AH, Lichtman MA. "The activation of lymphocyte plasma membrane (Na,K)-ATPase by EGTA is explained better by zinc than calcium chelation." The Journal of biological chemistry. 1981 Jul 10; 256(13):6629-32.
1981 Feb
Walters TE, Simon W, Chesler DA, Correia JA. "Attenuation correction in gamma emission computed tomography." Journal of computer assisted tomography. 1981 Feb; 5(1):89-94.
1980 Aug
Simon W, Blumenthal S. "A high resolution interactive image scanner." IEEE transactions on bio-medical engineering. 1980 Aug; 27(8):468-70.
1980 Jul
Simon W. "Avoiding megamouse experiments." Journal of toxicology and environmental health. 1980 Jul; 6(4):907-10.
1980 Jan
Simon W, Blumenthal S, Young JH, Elsbeck C. "The scientific laboratory instrument to computer coupler." IEEE transactions on bio-medical engineering. 1980 Jan; 27(1):55-7.
1979 Sep
Segel GB, Simon W, Lichtman MA. "Regulation of sodium and potassium transport in phytohemagglutinin-stimulated human blood lymphocytes." The Journal of clinical investigation. 1979 Sep; 64(3):834-41.
1978 Jan
Isenberg JF, Simon W. "Radionuclide axial tomography by half back-projection." Physics in medicine and biology. 1978 Jan; 23(1):154-8.
Lichtman MA, Chamberlain JK, Simon W, Santillo PA. "Parasinusoidal location of megakaryocytes in marrow: a determinant of platelet release." American journal of hematology. 1978 4(4):303-12.
Coleman, P.D.; Garvey, C.F.; Young, J.H.; Simon, W.;. "Semi-automatic tracking of neuronal processes". Computer Analysis of Neuronal Structures, Computers in Biology and Medicine, series editor Dr. George Moore, Plenum Press, NY. 1977; . Link
Eden, M.; Simon, W.;. "Direct measurement of red blood cell profiles". Three-Dimensional Imaging: Proceedings of SPIE's Twenty-first International Technical Symposium and Instrument Display, San Diego, CA. 1977; 120(3): 195. Link
Simon, W.; Walters, T.;. "A spinning mirror, autostereoscopic display". Three-Dimensional Imaging: Proceedings of SPIE's Twenty-first International Technical Symposium and Instrument Display, San Diego, CA. 1977; 120(3): 180. Link
Lichtman MA, Chamberlain JK, Simon W, Santillo PA. "The parasinusoidal location of megakaryocytes in marrow: a determinant of platelet release and a physiologic version of vascular invasion and metastasis." Transactions of the Association of American Physicians. 1977 90:313-23.
1976 Apr
Simon W, Eden M. "Three-dimensional measurements from scanning electron micrographs by electron scribing." The Review of scientific instruments. 1976 Apr; 47(4):443-4.
Simon, W.;. "Appendix In: Potassium transport in human blood lymphocytes treated with phytohemagglutinin by Segel, G.B. and Lichtman". M.A., Journal of Clinical Investigation. 1976; 58(3): 1558.
Walters, T.; Chesler, D.; Correia, J.; Brownell, G.L.; Simon, W.;. "Absorption correction in radionuclide axial tomography". Presented at Fourth International Conference on Medical Physics, Ottawa, Canada. 1976; . Link
1975 Sep 17
Neuman WF, Neuman MW, Sammon PJ, Simon W, Lane K. "The metabolism of labeled parathyroid hormone. III. Studies in rats." Calcified tissue research. 1975 Sep 17; 18(4):251-61.
Walters, T.E.; Simon, W.; Chesler, D.S.; Correia, J.A.;. "Radionuclide axial tomography corrected for internal gamma ray absorption". Information Processing in Scintigraphy: Proceedings of the IVth International Conference, Orsay, France. 1975; : 333.
Simon, W.;. "A three-dimensional computer display". Computer Graphics and Image Processing. 1975; 4(3): 396. Link
1974 Nov
Kay DB, Keyes JW, Simon W. "Radionuclide tomographic image reconstruction using Fourier transform techniques." Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1974 Nov; 15(11):981-6.
Simon, W.;. "Back-to-the-wall" effect?". Science, Nov. 1971, Jan 1974; Wall Street Journal, October 15, 1974. 1974; . Link
Keyes, J.W. Jr.; Kay, D.B.; Lees, D.E.B.; Simon, W.; Walters, T.E. ;. "Applied Comparison of Methods for Radionucleotide Transverse Section Tomography". In Proceedings of the First World Congress of Nuclear Medicine. World Federation of Nuclear Medicine and Biology. 1974; : 1281-1283. Link
Simon, W.; Walters, T.E.; Keyes, J.W. Jr. ;. "Experience with development of techniques of transverse section tomography as applied to". Techniques of Three-Dimensional Reconstruction: Proceedings of an International Workshop held at Brookhaven National Laboratory, Upton, NY. 1974; : 155. Link
1973 Aug
Garvey CF, Young JH, Coleman PD, Simon W. "Automated three-dimensional dendrite tracking system." Electroencephalography and clinical neurophysiology. 1973 Aug; 35(2):199-204.
1973 Apr
Gramiak R, Waag RC, Simon W. "Ciné ultrasound cardiography." Radiology. 1973 Apr; 107(1):175-80.
Keyes, J.W. Jr.; Simon, W. ;. "Computer techniques for radionuclide transverse section tomography and spatial (three-dimensional) imaging". Proceedings of the 3rd Symposium on Sharing of Computer Programs and Technology in Nuclear Medicine, USAEC, Oak Ridge. 1973; . Link
Lees, D.; Keyes, J.W. Jr.; Simon, W.;. "Reconstruction of radionuclide tomograms by the convolution method". Application of Optical Instrumentation in Medicine II. Proceedings, SPIE, Palos. 1973; .
Keyes, J.W. Jr.; Kay, D.B.; Simon, W.;. "Radionuclide three-dimensional spatial imaging". 21st Annual Meeting, Association of University Radiologists, Vancouver, BC. 1973; . Link
Keyes, J.W. Jr.; Kay, D.B.; Simon, W.;. "Digital reconstruction of three-dimensional radionuclide images". 20th Annual Meeting, Society of Nuclear Medicine, Miami Beach. 1973; . Link
Keyes, J.W. Jr.; Kay, D.B.; Lees, D.E.B.; Simon, W.;. "Comparison of methods for radionuclide tomography". Presented at RSNA Work-In-Progress Session, Chicago, November 28, 1973 and an updated version at "Optics in Diagnostic Medicine," Tucson, Arizona, January 10, 1974. 1973; . Link
Weiss, B.; Simon, W.;. "Quantitative perspectives on the long-term behavioral toxicity of methylmercury". Proceedings of 5th Rochester International Conference on Environmental Toxicity. University of Rochester, New York. 1972; . Link
1970 Jun
Simon W. "A scheme for accelerated floating point operation in small computers." Computers and biomedical research, an international journal. 1970 Jun; 3(3):238-40.
1970 Apr
Simon W. "A method of exponential separation applicable to small computers." Physics in medicine and biology. 1970 Apr; 15(2):355-60.
1970 Mar
Simon W. "The Rochester Ultimate Weapon. A high speed real-time interpretive computer language for biologists." Medical & biological engineering. 1970 Mar; 8(2):203-5.
1970 Jan
Simon W. "Reaching across the void." Journal of medical education. 1970 Jan; 45(1):60-1.
Simon, W.;. "A method of producing a three-dimensional cathode ray tube display". Behavioral Research Methods and Instrumentation. 1969; 1(3): 179. Link
Tretiak, O.J.; Eden, M.; Simon, W.;. "Pattern recognition and image processing: Internal structure from X-ray images". International Conference on Engineering in Medicine and Biology, Chicago. 1969; . Link
1968 Dec
Jones EA, Craigie A, Tavill AS, Simon W, Rosenoer VM. "Urea kinetics and the direct measurement of the synthetic rate of albumin utilizing [14C]carbonate." Clinical science. 1968 Dec; 35(3):553-64.
1968 Jun
Wright B, Simon W, Walsh BT. "A kinetic model of metabolism essential to differentiation in Dictyostelium discoideum." Proceedings of the National Academy of Sciences of the United States of America. 1968 Jun; 60(2):644-51.
1968 Jan
Simon W. "SNAP an interpretive real-time computer language for biology." Medical & biological engineering. 1968 Jan; 6(1):83-5.
1967 Nov
Houk J, Simon W. "Responses of Golgi tendon organs to forces applied to muscle tendon." Journal of neurophysiology. 1967 Nov; 30(6):1466-81.
Simon, W.; Costelli, W.P.; Rutstein, D.D.;. "Semi-automatic remote gas-liquid chromatographic analysis". Journal of Gas Chromatography. 1967; 5(3): 578. Link
1966 Nov
Herd JA, Leclair NR, Simon W. "Arterial pressure pulse contours during hemorrhage in anesthetized dogs." Journal of applied physiology. 1966 Nov; 21(6):1864-8.
Simon, W.;. "SNAP: Simplified numerical analysis and plotting program". Journal of the Association for the Advancement of Medical Instrumentation. 1966; . Link
Simon, W.; Drinker, P.A.;. "Laminar flow in a circular tube in longitudinal motion". Engineering Mechanics Division of Division Specialty Conference, Washington, D.C. 1966; . Link
1965 Nov
Simon W. "Photomicrography of deep fields." The Review of scientific instruments. 1965 Nov; 36(11):1654-5.
Simon, W.;. "The real-time sorting of neuro-electric action potentials in multiple unit studies". Electro-Encephalography and Clinical Neurophysiology. 1965; 18(3): 192. Link
Moore, G.P.; Simon, W.;. "Digital computer analysis of intercellular microelectrode recordings of neuronal activity". Meeting of the Biophysical Society, Chicago. 1964; . Link