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Brian James Blyth, M.D.

Brian James Blyth, M.D.

Emergency Medicine

UR Medicine Faculty The University of Rochester Medical Faculty Group (URMFG) consists of over 900 specialist and primary care providers spanning 19 departments. URMFG is certified by the National Committee for Quality Assurance.
Accountable Health Partner Accountable Health Partners (AHP) is a network of over 2,000 community and UR medical faculty and a dozen leading hospitals throughout the region. AHP offers a full range of care.
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About Me

Professional Background

Dr. Blyth is currently a Associate Professor of Clinical Emergency Medicine.

Certified Specialties

Emergency Medicine - American Board of Emergency Medicine

Credentials

Residency & Fellowship

Residency, Emergency Medicine, University of Rochester Medical Center. 2000 - 2002

Internship, Emergency Medicine, University of Rochester Medical Center. 1999 - 2000

Education

MD | University of Pittsburgh. 1999

Awards

Army Commendation Medal   . 2008 - 2008

Army Commendation Medal   . 2006

The Course in Scientific Management. 2005

Emergency Medicine Faculty Teaching Award. 2004

Army Commendation Medal   . 2003

Emergency Medicine Resident Teaching Award. 2002

Excellence in Emergency Medicine Award for Graduating Medical Students. 1999

Howard Hughes Medical Institute Fellowship Award. 1997 - 1998

University of Rochester Medical Center Departmental Research Fellow 2002-2003
Department of Emergency Medicine
Rochester, NY

Research

The research efforts of the Blyth laboratory focus on traumatic brain injury. The overarching goal of our laboratory is to reduce the morbidity and mortality associated with traumatic brain injury. To accomplish this goal we rely on a translational approach: both clinical and basic studies are us...
The research efforts of the Blyth laboratory focus on traumatic brain injury. The overarching goal of our laboratory is to reduce the morbidity and mortality associated with traumatic brain injury. To accomplish this goal we rely on a translational approach: both clinical and basic studies are used to identify and solve relevant research questions that might lead to improved therapeutics for this disease. Ultimately, promising therapies are tested for efficacy through clinical trials. Laboratory resources include a repository of patient samples collected through a multicenter research network that includes six medical centers located throughout upstate New York with 300,000 patient visits per year. Data and clinical samples collected through this network are housed at a central repository located within the laboratory. Physically, the laboratory consists of state of the art bench research facilities within the Center for Neural Development and Disease at the University of Rochester Medical Center. We utilize patient based studies as well as cell culture and animal models of disease. Several mouse and rat models of traumatic brain injury are utilized. Relevant questions are identified through studies of large numbers of human patients and examined in detail in animal models. Mechanistic insights gleaned through this approach may then allow for novel therapeutics that can then be developed for clinical trials.

Publications

Journal Articles

Subject-specific increases in serum S-100B distinguish sports-related concussion from sports-related exertion.

Kiechle K, Bazarian JJ, Merchant-Borna K, Stoecklein V, Rozen E, Blyth B, Huang JH, Dayawansa S, Kanz K, Biberthaler P

PloS one.. 2014 9 (1):e84977. Epub 01/08/2014.

Classification accuracy of serum Apo A-I and S100B for the diagnosis of mild traumatic brain injury and prediction of abnormal initial head computed tomography scan.

Bazarian JJ, Blyth B, He H, Mookerjee S, Jones C, Kiechle K, Moynihan R, Wojcik S, Grant WD, Secreti L, Triner W, Moscati R, Leinhart A, Ellis G, Khan J

Journal of neurotrauma.. 2013 October 1530 (20):1747-54. Epub 08/24/2013.

Elevated serum ubiquitin carboxy-terminal hydrolase L1 is associated with abnormal blood-brain barrier function after traumatic brain injury.

Blyth B, Farahvar A, He H, Nayak A, Yang C, Shaw G, Bazarian JJ

Journal of neurotrauma.. 2011 December 28 (12):2453-62. Epub 08/08/2011.

Traumatic alterations in consciousness: traumatic brain injury.

Blyth BJ, Bazarian JJ

Emergency medicine clinics of North America.. 2010 August 28 (3):571-94. Epub 1900 01 01.

Sex differences in outcome after mild traumatic brain injury.

Bazarian JJ, Blyth B, Mookerjee S, He H, McDermott M

Journal of neurotrauma.. 2010 March 27 (3):527-39. Epub 1900 01 01.

Validation of serum markers for blood-brain barrier disruption in traumatic brain injury.

Blyth B, Farhavar A, Gee C, Hawthorn B, He H, Nayak A, Stocklein V, Bazarian JJ

Journal of neurotrauma.. 2009 September 26 (9):1497-1507. Epub 1900 01 01.

Diffusion tensor imaging detects clinically important axonal damage after mild traumatic brain injury: a pilot study.

Bazarian JJ, Zhong J, Blyth B, Zhu T, Kavcic V, Peterson D

Journal of neurotrauma.. 2007 September 24 (9):1447-59. Epub 1900 01 01.

Impact of creatine kinase correction on the predictive value of S-100B after mild traumatic brain injury.

Bazarian JJ, Beck C, Blyth B, von Ahsen N, Hasselblatt M

Restorative neurology and neuroscience.. 2006 24 (3):163-72. Epub 1900 01 01.

The neurosteroid allopregnanolone modulates oxytocin expression in the hypothalamic paraventricular nucleus.

Blyth BJ, Hauger RL, Purdy RH, Amico JA.

AM. J. Physiol. 2000; 278(3): R684-91.