Kathleen E. McGrath, Ph.D.

Kathleen E. McGrath, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 703
Rochester, NY 14642

Office: (585) 275-5073

Journal Articles

Showing all 43 journal articles available.

2017 Jan 1
McGrath KE, Catherman SC, Palis J. "Delineating stages of erythropoiesis using imaging flow cytometry." Methods : a companion to Methods in enzymology. 2017 Jan 1; 112:68-74. Epub 2016 Aug 28.
2016 Sep 22
Gnanapragasam MN, McGrath KE, Catherman S, Xue L, Palis J, Bieker JJ. "EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation." Blood. 2016 Sep 22; 128(12):1631-41. Epub 2016 Aug 01.
2016 Feb
Frame JM, Fegan KH, Conway SJ, McGrath KE, Palis J. "Definitive Hematopoiesis in the Yolk Sac Emerges from Wnt-Responsive Hemogenic Endothelium Independently of Circulation and Arterial Identity." Stem cells. 2016 Feb; 34(2):431-44. Epub 2015 Oct 23.
Niswander LM, Palis J, McGrath KE. "Imaging Flow Cytometric Analysis of Primary Bone Marrow Megakaryocytes." Methods in molecular biology. 2016 1389:265-77.
2015 Dec
McGrath KE, Frame JM, Palis J. "Early hematopoiesis and macrophage development." Seminars in immunology. 2015 Dec; 27(6):379-87. Epub 2016 Mar 25.
2015 Aug
McGrath KE. "Utilization of imaging flow cytometry to define intermediates of megakaryopoiesis in vivo and in vitro." Journal of immunological methods. 2015 Aug; 423:45-51. Epub 2015 Mar 17.
2015 Jun 30
McGrath KE, Frame JM, Fegan KH, Bowen JR, Conway SJ, Catherman SC, Kingsley PD, Koniski AD, Palis J. "Distinct Sources of Hematopoietic Progenitors Emerge before HSCs and Provide Functional Blood Cells in the Mammalian Embryo." Cell reports. 2015 Jun 30; 11(12):1892-904. Epub 2015 Jun 18.
2015 Jun 9
Kim AR, Olsen JL, England SJ, Huang YS, Fegan KH, Delgadillo LF, McGrath KE, Kingsley PD, Waugh RE, Palis J. "Bmi-1 Regulates Extensive Erythroid Self-Renewal." Stem cell reports. 2015 Jun 9; 4(6):995-1003. Epub 2015 May 28.
2014 Aug
McGrath KE, Fegan K, Catherman S, Palis J. "Emergence of the neutrophil lineage in the mammalian embryo." Experimental hematology. 2014 Aug; 42(8 Suppl):S13.
2014 Jul 10
Niswander LM, Fegan KH, Kingsley PD, McGrath KE, Palis J. "SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury." Blood. 2014 Jul 10; 124(2):277-86. Epub 2014 Apr 15.
2014 Jun 19
McGrath KE. "Red cell island dances: switching hands." Blood. 2014 Jun 19; 123(25):3847-8.
2014 Apr
Niswander LM, McGrath KE, Kennedy JC, Palis J. "Improved quantitative analysis of primary bone marrow megakaryocytes utilizing imaging flow cytometry." Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2014 Apr; 85(4):302-12. Epub 2014 Jan 16.
Cadiz-Rivera B, Fromm G, de Vries C, Fields J, McGrath KE, Fiering S, Bulger M. "The chromatin "landscape" of a murine adult ?-globin gene is unaffected by deletion of either the gene promoter or a downstream enhancer." PloS one. 2014 9(5):e92947. Epub 2014 May 09.
2013 Dec
Frame JM, McGrath KE, Palis J. "Erythro-myeloid progenitors: "definitive" hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells." Blood cells, molecules & diseases. 2013 Dec; 51(4):220-5. Epub 2013 Oct 02.
2013 Feb 7
Kingsley PD, Greenfest-Allen E, Frame JM, Bushnell TP, Malik J, McGrath KE, Stoeckert CJ, Palis J. "Ontogeny of erythroid gene expression." Blood. 2013 Feb 7; 121(6):e5-e13. Epub 2012 Dec 12.
2013 Feb
Porter RL, Georger M, Bromberg O, McGrath KE, Frisch BJ, Becker MW, Calvi LM. "Prostaglandin E2 increases hematopoietic stem cell survival and accelerates hematopoietic recovery after radiation injury." Stem cells. 2013 Feb; 31(2):372-83.
2012 Sep 20
Peslak SA, Wenger J, Bemis JC, Kingsley PD, Koniski AD, McGrath KE, Palis J. "EPO-mediated expansion of late-stage erythroid progenitors in the bone marrow initiates recovery from sublethal radiation stress." Blood. 2012 Sep 20; 120(12):2501-11. Epub 2012 Aug 13.
2012 Jul 17
Sturgeon CM, Chicha L, Ditadi A, Zhou Q, McGrath KE, Palis J, Hammond SM, Wang S, Olson EN, Keller G. "Primitive erythropoiesis is regulated by miR-126 via nonhematopoietic Vcam-1+ cells." Developmental cell. 2012 Jul 17; 23(1):45-57. Epub 2012 Jun 28.
2011 May 12
Fromm G, Cadiz-Rivera B, de Vries C, Getman M, McGrath KE, Kingsley PD, Fields J, Fiering S, Bulger M. "An embryonic stage-specific enhancer within the murine ?-globin locus mediates domain-wide histone hyperacetylation." Blood. 2011 May 12; 117(19):5207-14. Epub 2011 Feb 14.
2011 Apr 28
McGrath KE, Frame JM, Fromm GJ, Koniski AD, Kingsley PD, Little J, Bulger M, Palis J. "A transient definitive erythroid lineage with unique regulation of the ?-globin locus in the mammalian embryo." Blood. 2011 Apr 28; 117(17):4600-8. Epub 2011 Mar 04.
2011 Apr
Peslak SA, Wenger J, Bemis JC, Kingsley PD, Frame JM, Koniski AD, Chen Y, Williams JP, McGrath KE, Dertinger SD, Palis J. "Sublethal radiation injury uncovers a functional transition during erythroid maturation." Experimental hematology. 2011 Apr; 39(4):434-45. Epub 2011 Feb 01.
2011 Mar 3
England SJ, McGrath KE, Frame JM, Palis J. "Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus." Blood. 2011 Mar 3; 117(9):2708-17. Epub 2010 Dec 02.
2010 Nov 1
Berahovich RD, Zabel BA, Penfold ME, Lewén S, Wang Y, Miao Z, Gan L, Pereda J, Dias J, Slukvin II, McGrath KE, Jaen JC, Schall TJ. "CXCR7 protein is not expressed on human or mouse leukocytes." The Journal of immunology : official journal of the American Association of Immunologists. 2010 Nov 1; 185(9):5130-9. Epub 2010 Oct 01.
Palis J, Malik J, McGrath KE, Kingsley PD. "Primitive erythropoiesis in the mammalian embryo." The International journal of developmental biology. 2010 54(6-7):1011-8.
2008 Jul 31
McGrath KE, Bushnell TP, Palis J. "Multispectral imaging of hematopoietic cells: where flow meets morphology." Journal of immunological methods. 2008 Jul 31; 336(2):91-7. Epub 2008 May 15.
2008 Mar 1
Tober J, McGrath KE, Palis J. "Primitive erythropoiesis and megakaryopoiesis in the yolk sac are independent of c-myb." Blood. 2008 Mar 1; 111(5):2636-9. Epub 2008 Jan 03.
2008 Feb 15
McGrath KE, Kingsley PD, Koniski AD, Porter RL, Bushnell TP, Palis J. "Enucleation of primitive erythroid cells generates a transient population of "pyrenocytes" in the mammalian fetus." Blood. 2008 Feb 15; 111(4):2409-17. Epub 2007 Nov 21.
2007 Feb 15
Tober J, Koniski A, McGrath KE, Vemishetti R, Emerson R, de Mesy-Bentley KK, Waugh R, Palis J. "The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis." Blood. 2007 Feb 15; 109(4):1433-41. Epub 2006 Oct 24.
2006 Feb 15
Kingsley PD, Malik J, Emerson RL, Bushnell TP, McGrath KE, Bloedorn LA, Bulger M, Palis J. ""Maturational" globin switching in primary primitive erythroid cells." Blood. 2006 Feb 15; 107(4):1665-72. Epub 2005 Nov 01.
Tober,J. M.; Koniski,A.; McGrath,K. E.; Vemishetti,R.; Emerson,R.; de Mesy-Bentley,K. K.; Waugh,R.; Palis,J.;. "The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis". Blood. 2006; . Link
2005 Sep
McGrath KE, Palis J. "Hematopoiesis in the yolk sac: more than meets the eye." Experimental hematology. 2005 Sep; 33(9):1021-8.
2004 Dec
Reynolds SD, Giangreco A, Hong KU, McGrath KE, Ortiz LA, Stripp BR. "Airway injury in lung disease pathophysiology: selective depletion of airway stem and progenitor cell pools potentiates lung inflammation and alveolar dysfunction." American journal of physiology. Lung cellular and molecular physiology. 2004 Dec; 287(6):L1256-65. Epub 2004 Aug 06.
2003 Mar 1
McGrath KE, Koniski AD, Malik J, Palis J. "Circulation is established in a stepwise pattern in the mammalian embryo." Blood. 2003 Mar 1; 101(5):1669-76. Epub 2002 Oct 24.
2003 Feb 7
Ji RP, Phoon CK, Aristizábal O, McGrath KE, Palis J, Turnbull DH. "Onset of cardiac function during early mouse embryogenesis coincides with entry of primitive erythroblasts into the embryo proper." Circulation research. 2003 Feb 7; 92(2):133-5.
2001 Jun
Keith Ho HC, McGrath KE, Brodbeck KC, Palis J, Schick BP. "Serglycin proteoglycan synthesis in the murine uterine decidua and early embryo." Biology of reproduction. 2001 Jun; 64(6):1667-76.
2001 Apr
Kingsley PD, McGrath KE, Maltby KM, Koniski AD, Ramchandran R, Palis J. "Subtractive hybridization reveals tissue-specific expression of ahnak during embryonic development." Development, growth & differentiation. 2001 Apr; 43(2):133-43.
1999 Sep 15
McGrath KE, Koniski AD, Maltby KM, McGann JK, Palis J. "Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4." Developmental biology. 1999 Sep 15; 213(2):442-56.
1997 Dec 19
McGrath KE, Seidler FJ, Slotkin TA. "Convergent control of serotonin transporter expression by glucocorticoids and cocaine in fetal and neonatal rat brain." Brain research. Developmental brain research. 1997 Dec 19; 104(1-2):209-13.
1997 Oct
McGrath KE, Palis J. "Expression of homeobox genes, including an insulin promoting factor, in the murine yolk sac at the time of hematopoietic initiation." Molecular reproduction and development. 1997 Oct; 48(2):145-53.
1997 Jan
McGrath KE, Smothers JF, Dadd CA, Madireddi MT, Gorovsky MA, Allis CD. "An abundant nucleolar phosphoprotein is associated with ribosomal DNA in Tetrahymena macronuclei." Molecular biology of the cell. 1997 Jan; 8(1):97-108.
1995 Jul 1
Palis J, McGrath KE, Kingsley PD. "Initiation of hematopoiesis and vasculogenesis in murine yolk sac explants." Blood. 1995 Jul 1; 86(1):156-63.
McGrath KE, Yu SM, Heruth DP, Kelly AA, Gorovsky MA. "Regulation and evolution of the single alpha-tubulin gene of the ciliate Tetrahymena thermophila." Cell motility and the cytoskeleton. 1994 27(3):272-83.
Gaertig J, Thatcher TH, McGrath KE, Callahan RC, Gorovsky MA. "Perspectives on tubulin isotype function and evolution based on the observation that Tetrahymena thermophila microtubules contain a single alpha- and beta-tubulin." Cell motility and the cytoskeleton. 1993 25(3):243-53.


Campbell RA, McGrath KE. "Polyamine Stress: A Variable Nonspecific Component of Disease?". Polyamines: Basic Clinical Aspects. AE Inahori et al. The Netherlands: VNU Science Press, 1984. 487-499