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William H. Merigan, Ph.D.

Contact Information

Phone Numbers

Office: (585) 275-4872

Research Labs

Biography

Professional Background

Dr. Merigan's research examines the role of retinal ganglion cells in visual perception in the primate (human and macaque). The primate retina contains at least 14 different types of retinal ganglion cells, and each type forms a complete network across the retina. Because the size, shape andprojections of each of the cell types is distinctive, it is thought that they may play quite different and possibly independent roles invisual function,but at present relatively little is known about this question. Some clues about possible functions of different ganglion cell classes comes from their structure (some extend across large swaths of retina, while others get input from tiny regions of retina), their physiology (some ganglion cells respond to color, while others are color blind), and their projections into the brain (some ganglion cells project to visual cortex while others reach the superchiasmatic nucleus, which is thought to be important in diurnal rhythms).

Credentials

Faculty Appointments

Education

1967
BA | Boston College
Psychology

1972
MS | Univ of Maryland
Psychology

1975
PhD | Univ of Maryland
Psychology, All Other

Publications

Journal Articles

2/2015
Kotterman MA, Yin L, Strazzeri JM, Flannery JG, Merigan WH, Schaffer DV. "Antibody neutralization poses a barrier to intravitreal adeno-associated viral vector gene delivery to non-human primates." Gene therapy.. 2015 Feb 0; 22(2):116-26. Epub 2014 Dec 11.

1/1/2015
Yang Q, Yin L, Nozato K, Zhang J, Saito K, Merigan WH, Williams DR, Rossi EA. "Calibration-free sinusoidal rectification and uniform retinal irradiance in scanning light ophthalmoscopy." Optics letters.. 2015 Jan 1; 40(1):85-8.

5/7/2014
Yin L, Masella B, Dalkara D, Zhang J, Flannery JG, Schaffer DV, Williams DR, Merigan WH. "Imaging light responses of foveal ganglion cells in the living macaque eye." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2014 May 7; 34(19):6596-605.

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