Karlene K. Gunter, Ph.D.

Karlene K. Gunter, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 712
Rochester, NY 14642

Office: (585) 275-3753
Fax: (585) 275-6007

Journal Articles

Showing all 46 journal articles available.

2013 Jan
Gunter TE, Gerstner B, Gunter KK, Malecki J, Gelein R, Valentine WM, Aschner M, Yule DI. "Manganese transport via the transferrin mechanism." Neurotoxicology. 2013 Jan; 34:118-27. Epub 2012 Nov 09.
2010 Nov 15
Gunter TE, Gerstner B, Lester T, Wojtovich AP, Malecki J, Swarts SG, Brookes PS, Gavin CE, Gunter KK. "An analysis of the effects of Mn2+ on oxidative phosphorylation in liver, brain, and heart mitochondria using state 3 oxidation rate assays." Toxicology and applied pharmacology. 2010 Nov 15; 249(1):65-75. Epub 2010 Aug 26.
2009 Jul
Gunter TE, Gavin CE, Gunter KK. "The case for manganese interaction with mitochondria." Neurotoxicology. 2009 Jul; 30(4):727-9. Epub 2009 May 22.
2009 Jan 1
Vanwinkle BA, de Mesy Bentley KL, Malecki JM, Gunter KK, Evans IM, Elder A, Finkelstein JN, Oberdörster G, Gunter TE. "Nanoparticle (NP) uptake by type I alveolar epithelial cells and their oxidant stress response." Nanotoxicology. 2009 Jan 1; 3(4):307-318.
2006 Sep
Gunter TE, Gavin CE, Aschner M, Gunter KK. "Speciation of manganese in cells and mitochondria: a search for the proximal cause of manganese neurotoxicity." Neurotoxicology. 2006 Sep; 27(5):765-76. Epub 2006 May 07.
Gunter KK, Aschner M, Miller LM, Eliseev R, Salter J, Anderson K, Gunter TE. "Determining the oxidation states of manganese in NT2 cells and cultured astrocytes." Neurobiology of aging. 2006 27(12):1816-26. Epub 2005 Nov 14.
2005 Jul 15
Gunter KK, Aschner M, Miller LM, Eliseev R, Salter J, Anderson K, Hammond S, Gunter TE. "Determining the oxidation states of manganese in PC12 and nerve growth factor-induced PC12 cells." Free radical biology & medicine. 2005 Jul 15; 39(2):164-81. Epub 2005 Mar 31.
2004 Jun 1
Gunter TE, Yule DI, Gunter KK, Eliseev RA, Salter JD. "Calcium and mitochondria." FEBS letters. 2004 Jun 1; 567(1):96-102.
2004 Jan
Gunter TE, Miller LM, Gavin CE, Eliseev R, Salter J, Buntinas L, Alexandrov A, Hammond S, Gunter KK. "Determination of the oxidation states of manganese in brain, liver, and heart mitochondria." Journal of neurochemistry. 2004 Jan; 88(2):266-80.
2003 Oct 1
Eliseev RA, Gunter KK, Gunter TE. "Bcl-2 prevents abnormal mitochondrial proliferation during etoposide-induced apoptosis." Experimental cell research. 2003 Oct 1; 289(2):275-81.
2003 Apr 18
Eliseev RA, Salter JD, Gunter KK, Gunter TE. "Bcl-2 and tBid proteins counter-regulate mitochondrial potassium transport." Biochimica et biophysica acta. 2003 Apr 18; 1604(1):1-5.
2002 Jul
Gunter KK, Miller LM, Aschner M, Eliseev R, Depuis D, Gavin CE, Gunte TE. "XANES spectroscopy: a promising tool for toxicology: a tutorial." Neurotoxicology. 2002 Jul; 23(2):127-46.
2002 Jun 10
Zuscik MJ, D'Souza M, Ionescu AM, Gunter KK, Gunter TE, O'Keefe RJ, Schwarz EM, Puzas JE, Rosier RN. "Growth plate chondrocyte maturation is regulated by basal intracellular calcium." Experimental cell research. 2002 Jun 10; 276(2):310-9.
2002 Feb
Eliseev RA, Gunter KK, Gunter TE. "Bcl-2 sensitive mitochondrial potassium accumulation and swelling in apoptosis." Mitochondrion. 2002 Feb; 1(4):361-70.
Gunter, K.; Miller, K., L.; Aschner, M., M.; Eliseev, R.; Depuis, D.; Gavin, C. E.; Gunter, T. E.;. "XANES spectroscopy: A promising tool for Toxicology: A tutorial". Neurotox. 2002; 23(3): 127-146. Link
2001 May
Gunter KK, Gunter TE. "Measurements of intracellular free calcium concentration in biological systems." Current protocols in toxicology. 2001 May; Chapter 2:Unit 2.5.
2001 Apr 2
Buntinas L, Gunter KK, Sparagna GC, Gunter TE. "The rapid mode of calcium uptake into heart mitochondria (RaM): comparison to RaM in liver mitochondria." Biochimica et biophysica acta. 2001 Apr 2; 1504(2-3):248-61.
Eliseev, R.A.; Gunter, K.K.; Gunter, T.E.;. "Bcl-2 sensitive mitochondrial potassium accumulation and". Mitochondrion. 2001; 1504(3): 248-61. Link
Gunter TE, Gunter KK. "Uptake of calcium by mitochondria: transport and possible function." IUBMB life. 2001 52(3-5):197-204.
Pfeiffer DR, Gunter TE, Eliseev R, Broekemeier KM, Gunter KK. "Release of Ca2+ from mitochondria via the saturable mechanisms and the permeability transition." IUBMB life. 2001 52(3-5):205-12.
2000 Jul
Chen K, Gunter K, Maines MD. "Neurons overexpressing heme oxygenase-1 resist oxidative stress-mediated cell death." Journal of neurochemistry. 2000 Jul; 75(1):304-13.
Gavin CE, Gunter KK, Gunter TE. "Manganese and calcium transport in mitochondria: implications for manganese toxicity." Neurotoxicology. 1999 20(2-3):445-53.
1998 Aug 10
Gunter TE, Buntinas L, Sparagna GC, Gunter KK. "The Ca2+ transport mechanisms of mitochondria and Ca2+ uptake from physiological-type Ca2+ transients." Biochimica et biophysica acta. 1998 Aug 10; 1366(1-2):5-15.
Gunter TE, Buntinas L, Sparagna GC, Gunter KK. "The interaction of mitochondria with pulses of calcium." BioFactors (Oxford, England). 1998 8(3-4):205-7.
1995 Nov 17
Sparagna GC, Gunter KK, Sheu SS, Gunter TE. "Mitochondrial calcium uptake from physiological-type pulses of calcium. A description of the rapid uptake mode." The Journal of biological chemistry. 1995 Nov 17; 270(46):27510-5.
1994 Oct
Gunter KK, Gunter TE. "Transport of calcium by mitochondria." Journal of bioenergetics and biomembranes. 1994 Oct; 26(5):471-85.
1994 Aug
Zuscik MJ, Gunter TE, Rosier RN, Gunter KK, Puzas JE. "Activation of phosphoinositide metabolism by parathyroid hormone in growth plate chondrocytes." Cell calcium. 1994 Aug; 16(2):112-22.
1994 Aug
Gunter TE, Gunter KK, Sheu SS, Gavin CE. "Mitochondrial calcium transport: physiological and pathological relevance." The American journal of physiology. 1994 Aug; 267(2 Pt 1):C313-39.
1994 May 15
Sparagna GC, Gunter KK, Gunter TE. "A system for producing and monitoring in vitro calcium pulses similar to those observed in vivo." Analytical biochemistry. 1994 May 15; 219(1):96-103.
1994 Mar
Baysal K, Jung DW, Gunter KK, Gunter TE, Brierley GP. "Na(+)-dependent Ca2+ efflux mechanism of heart mitochondria is not a passive Ca2+/2Na+ exchanger." The American journal of physiology. 1994 Mar; 266(3 Pt 1):C800-8.
Zuscik MJ, Puzas JE, Rosier RN, Gunter KK, Gunter TE. "Cyclic-AMP-dependent protein kinase activity is not required by parathyroid hormone to stimulate phosphoinositide signaling in chondrocytes but is required to transduce the hormone's proliferative effect." Archives of biochemistry and biophysics. 1994 315(2):352-61.
1992 Jul
Gavin CE, Gunter KK, Gunter TE. "Mn2+ sequestration by mitochondria and inhibition of oxidative phosphorylation." Toxicology and applied pharmacology. 1992 Jul; 115(1):1-5.
1991 Nov 15
Gunter KK, Zuscik MJ, Gunter TE. "The Na(+)-independent Ca2+ efflux mechanism of liver mitochondria is not a passive Ca2+/2H+ exchanger." The Journal of biological chemistry. 1991 Nov 15; 266(32):21640-8.
1991 Jan
Gavin CE, Gunter KK, Gunter TE. "Mn2+ transport across biological membranes may be monitored spectroscopically using the Ca2+ indicator dye antipyrylazo III." Analytical biochemistry. 1991 Jan; 192(1):44-8.
1990 Aug
Gunter TE, Zuscik MJ, Puzas JE, Gunter KK, Rosier RN. "Cytosolic free calcium concentrations in avian growth plate chondrocytes." Cell calcium. 1990 Aug; 11(7):445-57.
1990 Mar 1
Gavin CE, Gunter KK, Gunter TE. "Manganese and calcium efflux kinetics in brain mitochondria. Relevance to manganese toxicity." The Biochemical journal. 1990 Mar 1; 266(2):329-34.
1988 Sep
Gunter TE, Restrepo D, Gunter KK. "Conversion of esterified fura-2 and indo-1 to Ca2+-sensitive forms by mitochondria." The American journal of physiology. 1988 Sep; 255(3 Pt 1):C304-10.
Gunter TE, Wingrove DE, Banerjee S, Gunter KK. "Mechanisms of mitochondrial calcium transport." Advances in experimental medicine and biology. 1988 232:1-14.
1986 Jul
Jensen BD, Gunter KK, Gunter TE. "The efficiencies of the component steps of oxidative phosphorylation. II. Experimental determination of the efficiencies in mitochondria and examination of the equivalence of membrane potential and pH gradient in phosphorylation." Archives of biochemistry and biophysics. 1986 Jul; 248(1):305-23.
Gunter TE, Chace JH, Puskin JS, Gunter KK. "Mechanism of sodium independent calcium efflux from rat liver mitochondria." Biochemistry. 1983 22(26):6341-51.
1982 Feb
Gunter KK, Gunter TE, Jarkowski A, Rosier RN. "A method of resuspending small vesicles separated from suspension by protamine aggregation and centrifugation." Analytical biochemistry. 1982 Feb; 120(1):113-24.
1979 Jul 15
Rosier RN, Gunter TE, Tucker DA, Gunter KK. "A rapid method for separating small vesicles from suspension." Analytical biochemistry. 1979 Jul 15; 96(2):384-90.
1978 Apr 28
Gunter TE, Rosier RN, Tucker DA, Gunter KK. "Uptake of calcium and manganese by rat liver submitochondrial particles." Annals of the New York Academy of Sciences. 1978 Apr 28; 307:246-7.
1978 Jan 24
Gunter TE, Gunter KK, Puskin JS, Russell PR. "Efflux of Ca2+ and Mn2+ from rat liver mitochondria." Biochemistry. 1978 Jan 24; 17(2):339-45.
1976 Aug 24
Puskin JS, Gunter TE, Gunter KK, Russell PR. "Evidence for more than one Ca2+ transport mechanism in mitochondria." Biochemistry. 1976 Aug 24; 15(17):3834-42.
1972 Mar
Gunter TE, Gunter KK. "Pressure dependence of the helix-coil transition temperature for polynucleic acid helices." Biopolymers. 1972 Mar; 11(3):667-78.


Gunter, K. K., and T. E. Gunter. ""Measurements of intracellular free calcium concentration in biological systems."". Current Protocols in Toxicology. M. Maines, L.G. Costa, D. J. Reed, S. Sassa, and I. G. Sipes. New York, New York: John Wiley & Sons, 1999. 2.5.1-2.5.53
Sparagna, G., K. K. Gunter, S.-S. Sheu and T. E. Gunter.. ""Can mitochondria sequester pulses from physiological calcium pulses?"". What is Controlling Life?. E. Gnaiger, F. N. Gellerich and M. Wyss. Innsbruck, Austria: Innsbruck Univ. Press, 1994. 154-158
Gunter, K. K., R. N. Rosier, D. A. Tucker and T. E. Gunter.. ""Evidence for separate active mitochondrial efflux mechanisms for Ca2+ and Mn2+".". Calcium Binding Proteins and Cell Function. RH.Wasserman,RP.Corradino,E.Carafoli,RH.Kretsinger,DH.MacLennan,FL. Siege. Amsterdam, London, New York: Elsevier/North Holland, 1979. 498-500