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Barbara H. Iglewski, Ph.D.

Contact Information

Phone Numbers

Appointment: (585) 276-3000

Biography

Professional Background

Dr. Barbra Iglewski is Professor of Microbiology and Immunology and Director of International Programs at the University of Rochester Medical Center. She was the Chair of the Department of Microbiology and Immunology from 1986-2009 and the Vice Provost for Research and Graduate Education at the University of Rochester from 1995-1998.

Research

Dr. Iglewski has made many important contributions to the field of Pathogenic Microbiology and is best known for her elucidation of the molecular mechanism of action of Pseudomonas toxin A, the discovery of various other toxins and exoenzymes including the first type 3 secreted Pseudomonas toxin (exo S) and her landmark discovery that a type I quorum sensing system was a global regulator of virulence in a human pathogen. Dr. Iglewski has published over 150 research papers and book chapters and served as an editor of a number of books including the Encyclopedia of Microbiology. Dr. Iglewski is recognized by the Institute of Scientific Information as a highly cited scientist. This group comprises less than 0.5% of all publishing researchers. Her current research projects, supported by a merit award from the NIH, focus on the regulation of virulence and biofilm development in Pseudomonas aeruginosa.

Credentials

Faculty Appointments

Education

1960
BS | Allegheny College
Biology

1964
PhD | Penn State University
Microbiology, All Other

1962
MS | Penn State University
Microbiology, All Other

Awards

2009
Lifetime Mentor Award
Sponsor: URMC

2001 - 2010
NIH Health Merit Award R37

2001
Susan B. Anthony, Lifetime Achievement Award

1999
Arthur Kornberg, Research Award

1994
Alice Evans Award, American Society for Microbiology

1992
John W. Bullard Lecturer; Uniformed Services University of Health Sciences

1987
Honorary Lifetime Member - Sigma Delta Epsilon

1986
Fellow, American Academy of Microbiology

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Patents

Title: Autoinducer Molecules and Uses Therefor
U.S. Serial #: 10/844,037
Filed: May 11, 2004
Invented By: PesciEverett, EverettGreenberg, BarbaraIglewski, AndrewKende, JaredMilbank, JamesPearson

Title: Novel Autoinducer Molecules and Uses Therefor
U.S. Serial #: 09/945,325
Filed: Aug 31, 2001
Invented By: PesciEverett, EverettGreenberg, BarbaraIglewski, AndrewKende, JaredMilbank, JamesPearson

Publications

Journal Articles

10/2009
Van Alst NE, Wellington M, Clark VL, Haidaris CG, Iglewski BH. "Nitrite reductase NirS is required for type III secretion system expression and virulence in the human monocyte cell line THP-1 by Pseudomonas aeruginosa." Infection and immunity.. 2009 Oct 0; 77(10):4446-54. Epub 2009 Aug 03.

12/2008
Wagner VE, Iglewski BH. "P. aeruginosa Biofilms in CF Infection." Clinical reviews in allergy & immunology.. 2008 Dec 0; 35(3):124-34.

11/2007
Morici LA, Carterson AJ, Wagner VE, Frisk A, Schurr JR, Höner zu Bentrup K, Hassett DJ, Iglewski BH, Sauer K, Schurr MJ. "Pseudomonas aeruginosa AlgR represses the Rhl quorum-sensing system in a biofilm-specific manner." Journal of bacteriology.. 2007 Nov 0; 189(21):7752-64. Epub 2007 Aug 31.

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