Marc W. Halterman, M.D., Ph.D.

Marc W. Halterman, M.D., Ph.D.

Contact Information

Rochester General Hospital
1425 Portland Avenue
Department of Neurology
Rochester, NY 14621

Lab: (585) 275-6663

Research Bio

Dr. Halterman's laboratory studies the damage associated with global brain ischemia, with a particular focus on identifying novel therapeutic targets in transcriptional signaling networks. Using a variety of models, they study the effects of hypoxia-ischemia on both the adult nervous system as well as the progenitor cells active within the immature and adult brain. His laboratory is supported by grants from the NIH/NINDS. He also has extensive experience in the field of gene therapy and holds several patents in the areas of gene transfer, drug discovery and medical informatics.

Awards & Honors (National)

K99/R00 Fellowship | NIH/NINDS 2008 - Present
NIH Individual Pre-doctoral Combined MD PhD Fellowship | National instititues of Health | University of Rochester 1998

Awards & Honors (Local)

Henry C. Buswell Fellowship Award | Department of Medicine, URMC 2007
Doctor of Medicine with Distinction in Research | University of Rochester SMD | University of Rochester 2002
Gilbert B. Forbes Prize in Pediatric Research | University of Rochester 1994
Alpha Omega Alpha | University of Rochester


DUSP1/MKP-1 as a Therapeutic Target for Stroke

United States Serial NO.: 13/501,066
Filed Date: October 9, 2010
Title: Methods of Treatment and Screening Assays for HIF-1Alpha Regulation
Invented by: Marc Halterman

Recent Journal Articles

Showing the 5 most recent journal articles. 36 available »

2016 Jun
Sims MH, Fagnano M, Halterman JS, Halterman MW. "Provider impressions of the use of a mobile crowdsourcing app in medical practice." Health informatics journal. 2016 Jun; 22(2):221-31. Epub 2014 Aug 28.
2015 Apr 2
Hansen J, Snow C, Tuttle E, Ghoneim DH, Yang CS, Spencer A, Gunter SA, Smyser CD, Gurnett CA, Shinawi M, Dobyns WB, Wheless J, Halterman MW, Jansen LA, Paschal BM, Paciorkowski AR. "De novo mutations in SIK1 cause a spectrum of developmental epilepsies." American journal of human genetics. 2015 Apr 2; 96(4):682-90.
2014 Jul
Sims MH, Bigham J, Kautz H, Halterman MW. "Crowdsourcing medical expertise in near real time." Journal of hospital medicine. 2014 Jul; 9(7):451-6. Epub 2014 Apr 17.
2014 Jan 16
Matthews TA, Abel A, Demme C, Sherman T, Pan PW, Halterman MW, Parkkila S, Nehrke K. "Expression of the CHOP-inducible carbonic anhydrase CAVI-b is required for BDNF-mediated protection from hypoxia." Brain research. 2014 Jan 16; 1543:28-37. Epub 2013 Nov 23.
2012 Oct
Rininger A, Dejesus C, Totten A, Wayland A, Halterman MW. "MKP-1 antagonizes C/EBP? activity and lowers the apoptotic threshold after ischemic injury." Cell death and differentiation. 2012 Oct; 19(10):1634-43. Epub 2012 Apr 20.

Current Appointments

Associate Professor - Department of Neurology, Neurology - RGH (SMD) - Primary
Associate Professor - Department of Neuroscience (SMD)
Associate Professor - Department of Pediatrics (SMD)
Associate Professor - Center for Neural Development & Disease


Neurology - American Board of Psychiatry and Neurology


PhD | Microbiology | Univ Rochester Sch Med/Dent2002
MD | Medicine | Univ Rochester Sch Med/Dent2002
MS | Microbiology | Univ Rochester Sch Med/Dent1999
BS | Chemistry | Georgetown University1992

Post-Doctoral Training & Residency

Research at University of Rochester Medical Center01/01/2007 - 07/01/2007
Fellowship in Neurology at University of Rochester Medical Center
Residency in Neurology at University of Rochester Medical Center07/01/2003 - 06/30/2006
Internship in Internal Medicine at University of Rochester Medical Center06/24/2002 - 06/23/2003