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James R. Campbell, M.D., M.P.H.

Contact Information

Phone Numbers

Office: (585) 922-5658

Fax: (585) 922-3929

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Biography

Research

Dr. Campbell's research focuses on childhood lead toxicity, with two major projects underway:
Lead exposure and bone development: Basic-science research and our own preliminary studies show that lead exposure can adversely affect the development of bone density. The current study, being conducted with the Department of Orthopedics, is investigating whether lead exposure is a risk factor for the development of osteoporosis. We are conducting cross-sectional studies on 8-9 year old children, 18-19 year-old adolescents and 60-65 year old adults. All subjects are having their bone density measured by DEXA, and their bone lead level measured by KXRF; the URMC is one of the few institutions in the country to have KXRF technology. This project is funded by the National Institute of Environmental Health Sciences of the NIH.

Lead exposure and humoral immunity: Basic-science research studies show that lead exposure can adversely affect the development of antibodies after an infection or immunization. The current study, being conducted with the Cancer Institute, is investigating whether lead exposure is associated with lowered humoral response after vaccination with the HPV vaccine. We will enroll 11-12 year old girls with a broad-range of past lead exposure based on blood lead levels obtained at ages 1-3 years. All will have blood drawn before the vaccine is administered and at 1, 2, and 6 months after the first vaccine. This project is funded by the National Institute of Environmental Health Sciences at NIH.

Credentials

Specialties

  • Pediatrics

Education

1980
BS | University of Akron
Chemistry

1985
MD | Medical College Ohio
Medicine

1993
MPH | University of Rochester School of Medicine and Dentistry
Public Health

Post-doctoral Training & Residency

06/01/1985 - 06/30/1986
Internship in Pediatrics at University Hospitals Case Medical Center/Case Western Reserve University

07/01/1986 - 06/30/1988
Residency in Pediatrics at University Hospitals Case Medical Center/Case Western Reserve University

07/01/1988 - 06/30/1991
Fellowship in Pediatrics at University of Rochester School of Medicine & Dentistry

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Awards

2008
Member, Environmental Health Sciences Center Department of Environmental Medicine
Sponsor: University of Rochester
Location: Rochester, NY

1990
Rochester Academy of Medicine Library Award for the best paper in Medical History
Location: Rochester, NY

1985
Award for Academic Excellence in Pathology
Sponsor: Medical College Ohio
Location: Toledo, OH

1984
International Physicians of Northwest Ohio Scholarship
Sponsor: Medical College Ohio
Location: Toledo, OH

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Publications

Journal Articles

1/2011
Eisenberg KW, van Wijngaarden E, Fisher SG, Korfmacher KS, Campbell JR, Fernandez ID, Cochran J, Geltman PL. "Blood lead levels of refugee children resettled in Massachusetts, 2000 to 2007." American journal of public health.. 2011 Jan 0; 101(1):48-54. Epub 2010 Nov 18.

2011
Campbell JR. "Noninferiority trials". AAP Grand Rounds. 2011; 26(27).

7/2009
van Wijngaarden E, Campbell JR, Cory-Slechta DA. "Bone lead levels are associated with measures of memory impairment in older adults." Neurotoxicology.. 2009 Jul 0; 30(4):572-80. Epub 2009 May 27.

Books & Chapters

2007
Chapter Title: Lead poisoning
Book Title: Pediatric Clinical Advisor
Author List: Schaffer S, Campbell JR
Edited By: Garfunkel L
Published By: Mosby, Inc.2007 in St. Louis, MO

2007
Chapter Title: Intussusception
Book Title: Pediatric Clinical Advisor
Author List: Campbell JR
Edited By: Garfunkel L
Published By: Mosby, Inc.2007 in St. Louis, MO

2004
Chapter Title: Lead toxicity in the skeleton and its role in osteoporosis
Book Title: Nutrition and Bone Health
Author List: Puzas JE, Campbell JR, O'Keefe R, Rosier RN
Published By: Humana Press2004 in Totowa, NJ

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