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Kristin Scheible, M.D.

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Office: (585) 275-2972

Fax: (585) 756-7780

URMFGA member of the University of Rochester Medical Faculty Group

groupAn Accountable Health Partner

assignmentAccepting New Patients

Research Labs

Faculty Appointments

Patient Care Setting



As a neonatologist, Dr. Scheible's first and foremost goal is to provide excellent clinical care to her patients. She believes it is critical to work collaboratively with parents and bedside care providers to achieve the best outcomes for our babies, even in highly complex clinical situations. She encourages her care team to incorporate parental concerns into their daily assessment. By doing so, they can have a complete understanding of the patient's condition not just based on objective data available to us, but also the more subtle, and difficult to gather, "intuition" that only a parent can provide.

As part of the extracorporeal membrane oxygenation team (ECMO) team, Dr. Scheible has a special interest in caring for babies with persistent pulmonary hypertension, who struggle with adapting their circulation to an ex-utero environment. The complex, labile physiology and individual variability that such babies experience is exceptionally challenging, and requires an intensive, interdisciplinary approach to help them transition.

She feels that as neonatologists her job is not to just address the immediate problem, but also understand the long-term risks and benefits of each of our treatments. For her, balancing these short and long term goals, in cooperation with the parents and care team, is the most difficult and rewarding aspect of being a Neonatologist.

Dr. Scheible has received the "Patient and Family Centered Care Award" and holds "Bronze Star" level which is direct recognition from the families and patients in which she serves.


Advanced NICU care has improved survival of very premature infants, but their improved survival is accompanied by long-term complications such as impaired lung function. Infants born prematurely are highly susceptible to recurrent, severe respiratory viruses, suggesting a state of immune deficiency, specifically T cell immunity. They also suffer from diseases characterized by chronic inflammation associated with T cell activation, including bronchopulmonary dysplasia. This clinical paradox (T cells able to activate but not protect) is not well explained.

Our lab is interested in understanding the specific ways in which premature birth disrupts normal T cell development, and the impact of abnormal T cell development on a premature infant's clinical outcomes. Our lab primarily uses high parameter flow cytometric and high-throughput sequencing approaches to interrogate T cell receptor, cytokine signaling and functional differences that are intrinsic to T cells in various stages of fetal development. We work closely with investigators in Neonatology, Obstetrics, Infectious Diseases, Microbiology, Immunology, Genetics, Biostatistics and Computational Biology to understand in vitro T cell behavior in the context of longitudinal, translational human studies, including the Prematurity and Respiratory Outcomes Program and Respiratory Pathogens Research Center.

Dr. Scheible is a member of the Society for Pediatric Research and fellow, of the American Academy of Pediatrics.



  • Neonatal-Perinatal Medicine - American Board of Pediatrics
  • Pediatrics


MD | University of Rochester School of Medicine & Dentistry

Post-doctoral Training & Residency

07/01/2007 - 06/30/2010
Fellowship in Neonatology at University of Rochester Medical Center

07/01/2005 - 06/30/2007
Residency in Pediatrics at University of Rochester Medical Center

06/15/2004 - 06/30/2005
Internship in Pediatrics at University of Rochester Medical Center

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American Thoracic Society Abstract Award

University of Rochester Bronze Star
Location: University of Rochester

Patient-and Family-Centered Care Award

Patient-and Family-Centered Care Award

2011 - 2016
University of Rochester Strong Star
Location: University of Rochester

Pediatric Research Society, Young Investigator

NICHD Fellows Conference (nominated/selected attendee)

2008 - 2011
Ruth L. Kirschstein National Research Service Award, (T32, Francis Gigliotti)

Janet M. Glascow Memorial Achievement Award
Sponsor: University of Rochester School of Medicine and Dentistry
Location: Rochester, NY

Summer Fellowship in Anesthesiology

Outstanding Graduate in the Faculty of Arts and Letters
Sponsor: SUNY Buffalo
Location: Buffalo, NY

Lucia Maria Haupt Award in Anthropology
Sponsor: SUNY Buffalo
Location: Buffalo, NY

Kreyer Prize for Excellence in German
Location: University of Rochester

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Journal Articles

McDavid A, Corbett AM, Dutra JL, Straw AG, Topham DJ, Pryhuber GS, Caserta MT, Gill SR, Scheible KM, Holden-Wiltse J. "Eight practices for data management to enable team data science." Journal of clinical and translational science.. 2020 Jun 23; 5(1):e14. Epub 2020 Jun 23.

Grier A, McDavid A, Wang B, Qiu X, Java J, Bandyopadhyay S, Yang H, Holden-Wiltse J, Kessler HA, Gill AL, Huyck H, Falsey AR, Topham DJ, Scheible KM, Caserta MT, Pryhuber GS, Gill SR. "Neonatal gut and respiratory microbiota: coordinated development through time and space." Microbiome.. 2018 Oct 26; 6(1):193. Epub 2018 Oct 26.

Scheible KM, Emo J, Laniewski N, Baran AM, Peterson DR, Holden-Wiltse J, Bandyopadhyay S, Straw AG, Huyck H, Ashton JM, Tripi KS, Arul K, Werner E, Scalise T, Maffett D, Caserta M, Ryan RM, Reynolds AM, Ren CL, Topham DJ, Mariani TJ, Pryhuber GS. "T cell developmental arrest in former premature infants increases risk of respiratory morbidity later in infancy." JCI insight.. 2018 Feb 22; 3(4)Epub 2018 Feb 22.