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Robert A. Mooney, Ph.D.


Showing all 87 journal articles & 0 books available

Journal Articles

Favazzo LJ, Gill AL, Farnsworth CW, Mooney RA, Gill SR. "Response of and contributes to virulence and metabolism." Journal of bacteriology.. 2019 Feb 19; Epub 2019 Feb 19.

Moriarty TF, Harris LG, Mooney RA, Wenke JC, Riool M, Zaat SAJ, Moter A, Schaer TP, Khanna N, Kuehl R, Alt V, Montali A, Liu J, Zeiter S, Busscher HJ, Grainger DW, Richards RG. "Recommendations for design and conduct of preclinical in vivo studies of orthopedic device-related infection." Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2019 Jan 22; Epub 2019 Jan 22.

Farnsworth CW, Schott EM, Benvie A, Kates SL, Schwarz EM, Gill SR, Zuscik MJ, Mooney RA. "Exacerbated Foot Infections in Obese/Diabetic Mice Are Associated with Impaired Germinal Center Reactions, Ig Class Switching, and Humoral Immunity." The Journal of immunology : official journal of the American Association of Immunologists.. 2018 Jul 15; 201(2):560-572. Epub 2018 Jun 01.

Farnsworth CW, Schott EM, Benvie AM, Zukoski J, Kates SL, Schwarz EM, Gill SR, Zuscik MJ, Mooney RA. "Obesity/type 2 diabetes increases inflammation, periosteal reactive bone formation, and osteolysis during Staphylococcus aureus implant-associated bone infection." Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2018 Jun 0; 36(6):1614-1623. Epub 2018 Jan 03.

Schott EM, Farnsworth CW, Grier A, Lillis JA, Soniwala S, Dadourian GH, Bell RD, Doolittle ML, Villani DA, Awad H, Ketz JP, Kamal F, Ackert-Bicknell C, Ashton JM, Gill SR, Mooney RA, Zuscik MJ. "Targeting the gut microbiome to treat the osteoarthritis of obesity." JCI insight.. 2018 Apr 19; 3(8)Epub 2018 Apr 19.

Wexler O, Gough MS, Morgan MA, Mack CM, Apostolakos MJ, Doolin KP, Mooney RA, Arning E, Bottiglieri T, Pietropaoli AP. "Methionine Metabolites in Patients With Sepsis." Journal of intensive care medicine.. 2018 Jan 0; 33(1):37-47. Epub 2016 Sep 02.

Farnsworth CW, Schott EM, Jensen SE, Zukoski J, Benvie AM, Refaai MA, Kates SL, Schwarz EM, Zuscik MJ, Gill SR, Mooney RA. "Adaptive Upregulation of Clumping Factor A (ClfA) by Staphylococcus aureus in the Obese, Type 2 Diabetic Host Mediates Increased Virulence." Infection and immunity.. 2017 Jun 0; 85(6)Epub 2017 May 23.

Dar QA, Schott EM, Catheline SE, Maynard RD, Liu Z, Kamal F, Farnsworth CW, Ketz JP, Mooney RA, Hilton MJ, Jonason JH, Prawitt J, Zuscik MJ. "Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis." PloS one.. 2017 12(4):e0174705. Epub 2017 Apr 06.

Hamada D, Maynard R, Schott E, Drinkwater CJ, Ketz JP, Kates SL, Jonason JH, Hilton MJ, Zuscik MJ, Mooney RA. "Suppressive Effects of Insulin on Tumor Necrosis Factor-Dependent Early Osteoarthritic Changes Associated With Obesity and Type 2 Diabetes Mellitus." Arthritis & rheumatology.. 2016 Jun 0; 68(6):1392-402.

Beier EE, Inzana JA, Sheu TJ, Shu L, Puzas JE, Mooney RA. "Effects of Combined Exposure to Lead and High-Fat Diet on Bone Quality in Juvenile Male Mice." Environmental health perspectives.. 2015 Oct 0; 123(10):935-43. Epub 2015 Apr 10.

Farnsworth CW, Shehatou CT, Maynard R, Nishitani K, Kates SL, Zuscik MJ, Schwarz EM, Daiss JL, Mooney RA. "A humoral immune defect distinguishes the response to Staphylococcus aureus infections in mice with obesity and type 2 diabetes from that in mice with type 1 diabetes." Infection and immunity.. 2015 Jun 0; 83(6):2264-74. Epub 2015 Mar 23.

Barry CT, Hazard C, Hah Z, Cheng G, Partin A, Mooney RA, Chuang KH, Cao W, Rubens DJ, Parker KJ. "Shear wave dispersion in lean versus steatotic rat livers." Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.. 2015 Jun 0; 34(6):1123-9.

Shu L, Beier E, Sheu T, Zhang H, Zuscik MJ, Puzas EJ, Boyce BF, Mooney RA, Xing L. "High-fat diet causes bone loss in young mice by promoting osteoclastogenesis through alteration of the bone marrow environment." Calcified tissue international.. 2015 Apr 0; 96(4):313-23. Epub 2015 Feb 13.

Barry CT, Hah Z, Partin A, Mooney RA, Chuang KH, Augustine A, Almudevar A, Cao W, Rubens DJ, Parker KJ. "Mouse liver dispersion for the diagnosis of early-stage Fatty liver disease: a 70-sample study." Ultrasound in medicine & biology.. 2014 Apr 0; 40(4):704-13. Epub 2014 Jan 10.

David MA, Jones KH, Inzana JA, Zuscik MJ, Awad HA, Mooney RA. "Tendon repair is compromised in a high fat diet-induced mouse model of obesity and type 2 diabetes." PloS one.. 2014 9(3):e91234. Epub 2014 Mar 21.

Brown ML, Yukata K, Farnsworth CW, Chen DG, Awad H, Hilton MJ, O'Keefe RJ, Xing L, Mooney RA, Zuscik MJ. "Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus." PloS one.. 2014 9(6):e99656. Epub 2014 Jun 09.

Shi J, Liang Q, Wang Y, Mooney R, Boyce B, Xing L. "Use of a whole-slide imaging system to assess the presence and alteration of lymphatic vessels in joint sections of arthritic mice." Biotechnic & histochemistry : official publication of the Biological Stain Commission.. 2013 Nov 0; 88(8):428-39. Epub 2012 Nov 23.

Inzana JA, Kung M, Shu L, Hamada D, Xing LP, Zuscik MJ, Awad HA, Mooney RA. "Immature mice are more susceptible to the detrimental effects of high fat diet on cancellous bone in the distal femur." Bone.. 2013 Nov 0; 57(1):174-83. Epub 2013 Aug 14.

Mirando AJ, Liu Z, Moore T, Lang A, Kohn A, Osinski AM, O'Keefe RJ, Mooney RA, Zuscik MJ, Hilton MJ. "RBP-J?-dependent Notch signaling is required for murine articular cartilage and joint maintenance." Arthritis and rheumatism.. 2013 Oct 0; 65(10):2623-33.

Curtin WM, Menegus MA, Patru MM, Peterson CJ, Metlay LA, Mooney RA, Stanwood NL, Scheible AL, Dorgan A. "Midtrimester fetal herpes simplex-2 diagnosis by serology, culture and quantitative polymerase chain reaction." Fetal diagnosis and therapy.. 2013 33(2):133-6. Epub 2012 Oct 11.

Barry CT, Mills B, Hah Z, Mooney RA, Ryan CK, Rubens DJ, Parker KJ. "Shear wave dispersion measures liver steatosis." Ultrasound in medicine & biology.. 2012 Feb 0; 38(2):175-82. Epub 2011 Dec 16.

Clementi AH, Gaudy AM, Zimmers TA, Koniaris LG, Mooney RA. "Deletion of interleukin-6 improves pyruvate tolerance without altering hepatic insulin signaling in the leptin receptor-deficient mouse." Metabolism: clinical and experimental.. 2011 Nov 0; 60(11):1610-9. Epub 2011 May 31.

Sampson ER, Hilton MJ, Tian Y, Chen D, Schwarz EM, Mooney RA, Bukata SV, O'Keefe RJ, Awad H, Puzas JE, Rosier RN, Zuscik MJ. "Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis." Science translational medicine.. 2011 Sep 21; 3(101):101ra93.

Gough MS, Morgan MA, Mack CM, Darling DC, Frasier LM, Doolin KP, Apostolakos MJ, Stewart JC, Graves BT, Arning E, Bottiglieri T, Mooney RA, Frampton MW, Pietropaoli AP. "The ratio of arginine to dimethylarginines is reduced and predicts outcomes in patients with severe sepsis." Critical care medicine.. 2011 Jun 0; 39(6):1351-8.

Mooney RA, Sampson ER, Lerea J, Rosier RN, Zuscik MJ. "High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury." Arthritis research & therapy.. 2011 13(6):R198. Epub 2011 Dec 07.

Gaudy AM, Clementi AH, Campbell JS, Smrcka AV, Mooney RA. "Suppressor of cytokine signaling-3 is a glucagon-inducible inhibitor of PKA activity and gluconeogenic gene expression in hepatocytes." The Journal of biological chemistry.. 2010 Dec 31; 285(53):41356-65. Epub 2010 Oct 26.

Galloway CA, Ashton J, Sparks JD, Mooney RA, Smith HC. "Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes." Biochimica et biophysica acta.. 2010 Nov 0; 1802(11):976-85. Epub 2010 Jun 09.

Clementi AH, Gaudy AM, Rooijen NV, Pierce RH, Mooney RA. "Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling." Biochimica et biophysica acta.. 2009 Nov 0; 1792(11):1062-72. Epub 2009 Aug 20.

Thornburg LL, Knight KM, Peterson CJ, McCall KB, Mooney RA, Pressman EK. "Maternal serum alpha-fetoprotein values in type 1 and type 2 diabetic patients." American journal of obstetrics and gynecology.. 2008 Aug 0; 199(2):135.e1-5. Epub 2008 May 02.

Navaneethan, SD; Mooney, RA; James Sloand, J. "Pseudo-anion gap acidosis" . NDT Plus. 2008; 1(2): 94-96.

Mooney RA. "Counterpoint: Interleukin-6 does not have a beneficial role in insulin sensitivity and glucose homeostasis." Journal of applied physiology.. 2007 Feb 0; 102(2):816-8; discussion 818-9.

Chagnon MJ, Elchebly M, Uetani N, Dombrowski L, Cheng A, Mooney RA, Marette A, Tremblay ML. "Altered glucose homeostasis in mice lacking the receptor protein tyrosine phosphatase sigma." Canadian journal of physiology and pharmacology.. 2006 Jul 0; 84(7):755-63.

Klover PJ, Clementi AH, Mooney RA. "Interleukin-6 depletion selectively improves hepatic insulin action in obesity." Endocrinology.. 2005 Aug 0; 146(8):3417-27. Epub 2005 Apr 21.

LeVea CM, Reeder JE, Mooney RA. "EGF-dependent cell cycle progression is controlled by density-dependent regulation of Akt activation." Experimental cell research.. 2004 Jul 1; 297(1):272-84.

Klover PJ, Mooney RA. "Hepatocytes: critical for glucose homeostasis." The international journal of biochemistry & cell biology.. 2004 May 0; 36(5):753-8.

Baliff JP, Mooney RA. "New developments in prenatal screening for Down syndrome." American journal of clinical pathology.. 2003 Dec 0; 120 Suppl:S14-24.

Klover PJ, Zimmers TA, Koniaris LG, Mooney RA. "Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice." Diabetes.. 2003 Nov 0; 52(11):2784-9.

Arnold GL, Hyman SL, Mooney RA, Kirby RS. "Plasma amino acids profiles in children with autism: potential risk of nutritional deficiencies." Journal of autism and developmental disorders.. 2003 Aug 0; 33(4):449-54.

Pearce DA, McCall K, Mooney RA, Chattopadhyay S, Curran TM. "Altered amino acid levels in sera of a mouse model for juvenile neuronal ceroid lipofuscinoses." Clinica chimica acta; international journal of clinical chemistry.. 2003 Jun 0; 332(1-2):145-8.

Polliotti BM, Fry AG, Saller DN, Mooney RA, Cox C, Miller RK. "Second-trimester maternal serum placental growth factor and vascular endothelial growth factor for predicting severe, early-onset preeclampsia." Obstetrics and gynecology.. 2003 Jun 0; 101(6):1266-74.

Senn JJ, Klover PJ, Nowak IA, Zimmers TA, Koniaris LG, Furlanetto RW, Mooney RA. "Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes." The Journal of biological chemistry.. 2003 Apr 18; 278(16):13740-6. Epub 2003 Jan 30.

Mooney RA, LeVea CM. "The leukocyte common antigen-related protein LAR: candidate PTP for inhibitory targeting." Current topics in medicinal chemistry.. 2003 3(7):809-19.

Senn JJ, Klover PJ, Nowak IA, Mooney RA. "Interleukin-6 induces cellular insulin resistance in hepatocytes." Diabetes.. 2002 Dec 0; 51(12):3391-9.

Symons JR, LeVea CM, Mooney RA. "Expression of the leucocyte common antigen-related (LAR) tyrosine phosphatase is regulated by cell density through functional E-cadherin complexes." The Biochemical journal.. 2002 Jul 15; 365(Pt 2):513-9.

Mooney RA, Senn J, Cameron S, Inamdar N, Boivin LM, Shang Y, Furlanetto RW. "Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance." The Journal of biological chemistry.. 2001 Jul 13; 276(28):25889-93. Epub 2001 May 07.

Levea CM, Mcgary CT, Symons JR, Mooney RA. "PTP LAR expression compared to prognostic indices in metastatic and non-metastatic breast cancer." Breast cancer research and treatment.. 2000 Nov 0; 64(2):221-8.

Bleyle LA, Peng Y, Ellis C, Mooney RA. "Dissociation of PTPase levels from their modulation of insulin receptor signal transduction." Cellular signalling.. 1999 Oct 0; 11(10):719-25.

Hostetler MA, Arnold GL, Mooney R, Bennett MJ, Rinaldo P, Roe CR. "Hypoketotic hypoglycemic coma in a 21-month-old child." Annals of emergency medicine.. 1999 Sep 0; 34(3):394-8.

Saller DN, Canick JA, Kellner LH, Rose NC, Garza J, French CA, Mooney RA. "Maternal serum analyte levels in pregnancies with fetal Down syndrome resulting from translocations." American journal of obstetrics and gynecology.. 1997 Oct 0; 177(4):879-81.

Phung TL, Mooney RA, Kulas DT, Sparks CE, Sparks JD. "Suppression of the protein tyrosine phosphatase LAR reduces apolipoprotein B secretion by McA-RH7777 rat hepatoma cells." Biochemical and biophysical research communications.. 1997 Aug 18; 237(2):367-71.

Mooney RA, Kulas DT, Bleyle LA, Novak JS. "The protein tyrosine phosphatase LAR has a major impact on insulin receptor dephosphorylation." Biochemical and biophysical research communications.. 1997 Jun 27; 235(3):709-12.

Kulas DT, Goldstein BJ, Mooney RA. "The transmembrane protein-tyrosine phosphatase LAR modulates signaling by multiple receptor tyrosine kinases." The Journal of biological chemistry.. 1996 Jan 12; 271(2):748-54.

Kulas DT, Freund GG, Mooney RA. "The transmembrane protein-tyrosine phosphatase CD45 is associated with decreased insulin receptor signaling." The Journal of biological chemistry.. 1996 Jan 12; 271(2):755-60.

Mooney RA, Arvan DA, Saller DN, French CA, Peterson CJ. "Decreased maternal serum hCG levels with increasing gravidity and parity." Obstetrics and gynecology.. 1995 Dec 0; 86(6):900-5.

Kulas DT, Zhang WR, Goldstein BJ, Furlanetto RW, Mooney RA. "Insulin receptor signaling is augmented by antisense inhibition of the protein tyrosine phosphatase LAR." The Journal of biological chemistry.. 1995 Feb 10; 270(6):2435-8.

Freund GG, Wittig JG, Mooney RA. "The PI3-kinase serine kinase phosphorylates its p85 subunit and IRS-1 in PI3-kinase/IRS-1 complexes." Biochemical and biophysical research communications.. 1995 Jan 5; 206(1):272-8.

Way BA, Mooney RA. "Differential effects of phosphotyrosine phosphatase expression on hormone-dependent and independent pp60c-src activity." Molecular and cellular biochemistry.. 1994 Oct 26; 139(2):167-75.

Mooney RA, Peterson CJ, French CA, Saller DN, Arvan DA. "Effectiveness of combining maternal serum alpha-fetoprotein and hCG in a second-trimester screening program for Down syndrome." Obstetrics and gynecology.. 1994 Aug 0; 84(2):298-303.

Freund GG, Kulas DT, Way BA, Mooney RA. "Functional insulin and insulin-like growth factor-1 receptors are preferentially expressed in multiple myeloma cell lines as compared to B-lymphoblastoid cell lines." Cancer research.. 1994 Jun 15; 54(12):3179-85.

Way BA, Mooney RA. "Activation of phosphatidylinositol-3-kinase by platelet-derived growth factor and insulin-like growth factor-1 is inhibited by a transmembrane phosphotyrosine phosphatase." The Journal of biological chemistry.. 1993 Dec 15; 268(35):26409-15.

Freund GG, Kulas DT, Mooney RA. "Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226." The Journal of immunology : official journal of the American Association of Immunologists.. 1993 Aug 15; 151(4):1811-20.

Mooney RA, Freund GG, Way BA, Bordwell KL. "Expression of a transmembrane phosphotyrosine phosphatase inhibits cellular response to platelet-derived growth factor and insulin-like growth factor-1." The Journal of biological chemistry.. 1992 Nov 25; 267(33):23443-6.

Mooney RA, Bordwell KL. "Differential dephosphorylation of the insulin receptor and its 160-kDa substrate (pp160) in rat adipocytes." The Journal of biological chemistry.. 1992 Jul 15; 267(20):14054-60.

Mooney RA, Bordwell KL. "Insulin stimulates the tyrosine phosphorylation of a 61-kilodalton protein in rat adipocytes." Endocrinology.. 1992 Mar 0; 130(3):1533-8.

Wilbur DC, Willis J, Mooney RA, Fallon MA, Moynes R, di Sant'Agnese PA. "Estrogen and progesterone receptor detection in archival formalin-fixed, paraffin-embedded tissue from breast carcinoma: a comparison of immunohistochemistry with the dextran-coated charcoal assay." Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.. 1992 Jan 0; 5(1):79-84.

Mooney RA, Bordwell KL. "Counter-regulation by insulin and isoprenaline of a prominent fat-associated phosphoprotein doublet in rat adipocytes." The Biochemical journal.. 1991 Mar 1; 274 ( Pt 2):433-8.

Arvan, DA; Mooney, RA. "Maternal serum alpha-fetoprotein screening (MSAFP): A model program for clinical practice, education, and research in Pathology." Il Patologo Clinico. 1990; 9: 898-908.

Davis NS, DiSant'Agnese PA, Ewing JF, Mooney RA. "The neuroendocrine prostate: characterization and quantitation of calcitonin in the human gland." The Journal of urology.. 1989 Sep 0; 142(3):884-8.

Mooney RA, Green DA. "Insulin receptor dephosphorylation in permeabilized adipocytes is inhibitable by manganese and independent of receptor kinase activity." Biochemical and biophysical research communications.. 1989 Aug 15; 162(3):1200-6.

Mooney RA, Anderson DL. "Phosphorylation of the insulin receptor in permeabilized adipocytes is coupled to a rapid dephosphorylation reaction." The Journal of biological chemistry.. 1989 Apr 25; 264(12):6850-7.

Mooney RA, Bordwell KL, Luhowskyj S, Casnellie JE. "The insulin-like effect of vanadate on lipolysis in rat adipocytes is not accompanied by an insulin-like effect on tyrosine phosphorylation." Endocrinology.. 1989 Jan 0; 124(1):422-9.

Amatruda JM, Vallone BB, Schuster T, Mooney RA. "Importance of periodic reeducation of hospital-based nurses in capillary blood glucose monitoring and an evaluation of the usefulness of reflectance meters." The Diabetes educator.. 1989 15(5):435-9.

Mayer TK, Mooney RA. "Laboratory analyses for steroid hormone receptors, and their applications to clinical medicine." Clinica chimica acta; international journal of clinical chemistry.. 1988 Feb 29; 172(1):1-33.

Mooney RA, McGorty BL, French CA, Arvan DA. "An alpha-fetoprotein radioimmunoassay for use in maternal serum screening for Down's syndrome: limitations and improvements." Clinica chimica acta; international journal of clinical chemistry.. 1988 Feb 15; 171(2-3):325-31.

Mooney RA. "Use of digitonin-permeabilized adipocytes for cAMP studies." Methods in enzymology.. 1988 159:193-202.

Mooney RA, Swicegood CL, Marx RB. "Coupling of adenylate cyclase to lipolysis in permeabilized adipocytes: direct evidence that an antilipolytic effect of insulin is independent of adenylate cyclase." Endocrinology.. 1986 Nov 0; 119(5):2240-8.

Lee LA, Mooney RA, Woolf PD. "Clinical utility of measuring free thyroxin and free triiodothyronine in serum of critically ill patients by ultrafiltration." Clinical chemistry.. 1986 May 0; 32(5):797-800.

Mooney RA, McDonald JM. "In situ analysis of adenylate cyclase activity in permeabilized rat adipocytes: sensitivity to GTP, isoproterenol, and N6-(phenylisopropyl)adenosine." The International journal of biochemistry. 1986 18(8):713-8.

Mooney RA, Ebersohl RD, McDonald JM. "Insulin-mediated antilipolysis in permeabilized rat adipocytes." The Journal of biological chemistry.. 1984 Jun 25; 259(12):7701-4.

Mooney RA, McDonald JM. "Effect of phenylephrine on lipolysis in rat adipocytes: no evidence for an alpha-adrenergic mechanism." The International journal of biochemistry. 1984 16(1):55-9.

Mooney RA, Ebersohl RD, McDonald JM. "Novel approach to the study of the regulation of hormone-sensitive lipase in rat adipocytes. Permeabilization of cells with digitonin." European journal of biochemistry. 1983 Nov 15; 136(3):603-8.

Mooney RA, Smith CH, Zarkowsky HS. "Free bilirubin measurements in a patient with Crigler-Najjar syndrome after crush injury." The Journal of pediatrics.. 1983 Aug 0; 103(2):262-5.

Mooney RA, Lane MD. "Control of ketogenesis and fatty-acid synthesis at the mitochondrial branch-point for acetyl-CoA in the chick liver cell: effect of adenosine 3',5'-monophosphate." European journal of biochemistry. 1982 Jan 0; 121(2):281-7.

McDonald JM, Chan KM, Goewert RR, Mooney RA, Pershadsingh HA. "The (Ca2+ +Mg2+)-ATPase of adipocyte plasma membrane: regulation by calmodulin and insulin." Annals of the New York Academy of Sciences.. 1982 402:381-401.

Mooney RA, Lane MD. "Formation and turnover of triglyceride-rich vesicles in the chick liver cell. Effects of cAMP and carnitine on triglyceride mobilization and conversion to ketones." The Journal of biological chemistry.. 1981 Nov 25; 256(22):11724-33.

Lane MD, Mooney RA. "Tricarboxylic acid cycle intermediates and the control of fatty acid synthesis and ketogenesis." Current topics in cellular regulation. 1981 18:221-42.

Clinkenbeard KD, Reed WD, Mooney RA, Lane MD. "Intracellular localization of the 3-hydroxy-3-methylglutaryl coenzme A cycle enzymes in liver. Separate cytoplasmic and mitochondrial 3-hydroxy-3-methylglutaryl coenzyme A generating systems for cholesterogenesis and ketogenesis." The Journal of biological chemistry.. 1975 Apr 25; 250(8):3108-16.