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Mark P. Sowden, Ph.D.


Showing all 35 journal articles & 1 books available

Journal Articles

Lehmann DM, Galloway CA, MacElrevey C, Sowden MP, Wedekind JE, Smith HC. "Functional characterization of APOBEC-1 complementation factor phosphorylation sites." Biochimica et biophysica acta.. 2007 Mar 0; 1773(3):408-18. Epub 2006 Dec 08.

Bennett RP, Diner E, Sowden MP, Lees JA, Wedekind JE, Smith HC. "APOBEC-1 and AID are nucleo-cytoplasmic trafficking proteins but APOBEC3G cannot traffic." Biochemical and biophysical research communications.. 2006 Nov 10; 350(1):214-9. Epub 2006 Sep 18.

Ichikawa HT, Sowden MP, Torelli AT, Bachl J, Huang P, Dance GS, Marr SH, Robert J, Wedekind JE, Smith HC, Bottaro A. "Structural phylogenetic analysis of activation-induced deaminase function." The Journal of immunology : official journal of the American Association of Immunologists.. 2006 Jul 1; 177(1):355-61.

Sparks JD, Collins HL, Chirieac DV, Cianci J, Jokinen J, Sowden MP, Galloway CA, Sparks CE. "Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine-homocysteine S-methyltransferase." The Biochemical journal.. 2006 Apr 15; 395(2):363-71.

Lehmann DM, Galloway CA, Sowden MP, Smith HC. "Metabolic regulation of apoB mRNA editing is associated with phosphorylation of APOBEC-1 complementation factor." Nucleic acids research.. 2006 34(11):3299-308. Epub 2006 Jul 04.

Smith HC, Bottaro A, Sowden MP, Wedekind JE. "Activation induced deaminase: the importance of being specific." Trends in genetics : TIG.. 2004 Jun 0; 20(6):224-7.

Xie K, Sowden MP, Dance GS, Torelli AT, Smith HC, Wedekind JE. "The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1." Proceedings of the National Academy of Sciences of the United States of America.. 2004 May 25; 101(21):8114-9. Epub 2004 May 17.

Sowden MP, Lehmann DM, Lin X, Smith CO, Smith HC. "Identification of novel alternative splice variants of APOBEC-1 complementation factor with different capacities to support apolipoprotein B mRNA editing." The Journal of biological chemistry.. 2004 Jan 2; 279(1):197-206. Epub 2003 Oct 21.

Reeder JE, Sowden MP, Messing EM, Klover P, Villa-Moruzzi E, Ludlow JW. "Inducible expression of catalytically active type 1 serine/threonine protein phosphatase in a human carcinoma cell line." Cancer cell international. 2003 Jul 23; 3(1):12. Epub 2003 Jul 23.

Wedekind JE, Dance GS, Sowden MP, Smith HC. "Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business." Trends in genetics : TIG.. 2003 Apr 0; 19(4):207-16.

Galloway CA, Sowden MP, Smith HC. "Increasing the yield of soluble recombinant protein expressed in E. coli by induction during late log phase." BioTechniques.. 2003 Mar 0; 34(3):524-6, 528, 530.

Dance GS, Sowden MP, Cartegni L, Cooper E, Krainer AR, Smith HC. "Two proteins essential for apolipoprotein B mRNA editing are expressed from a single gene through alternative splicing." The Journal of biological chemistry.. 2002 Apr 12; 277(15):12703-9. Epub 2002 Jan 28.

Sowden MP, Ballatori N, Jensen KL, Reed LH, Smith HC. "The editosome for cytidine to uridine mRNA editing has a native complexity of 27S: identification of intracellular domains containing active and inactive editing factors." Journal of cell science.. 2002 Mar 1; 115(Pt 5):1027-39.

Giangreco A, Sowden MP, Mikityansky I, Smith HC. "Ethanol stimulates apolipoprotein B mRNA editing in the absence of de novo RNA or protein synthesis." Biochemical and biophysical research communications.. 2001 Dec 21; 289(5):1162-7.

Yang Y, Sowden MP, Yang Y, Smith HC. "Intracellular trafficking determinants in APOBEC-1, the catalytic subunit for cytidine to uridine editing of apolipoprotein B mRNA." Experimental cell research.. 2001 Jul 15; 267(2):153-64.

Sowden, M.P. and Smith, H.C. "Commitment of Apolipoprotein B PremRNA to the Splicing Pathway Regulates C to U Editing Site Utilization". Biochem Journal. 2001; 359(3): 697-705.

Dance GS, Sowden MP, Yang Y, Smith HC. "APOBEC-1 dependent cytidine to uridine editing of apolipoprotein B RNA in yeast." Nucleic acids research.. 2000 Jan 15; 28(2):424-9.

Yang, Y.; Sowden, M.P. and Smith, H.C. "Induction of cytidine to uridine Editing on cytoplasmic Apolipoprotein B mRNA by overexpressing APOBEC-1". J. Biol. Chemistry. 2000; 275(30): 22663-22669.

Siddiqui JF, Van Mater D, Sowden MP, Smith HC. "Disproportionate relationship between APOBEC-1 expression and apolipoprotein B mRNA editing activity." Experimental cell research.. 1999 Oct 10; 252(1):154-64.

Sowden MP, Collins HL, Smith HC, Garrow TA, Sparks JD, Sparks CE. "Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase." The Biochemical journal.. 1999 Aug 1; 341 ( Pt 3):639-45.

Sowden, M.P. and Smith, H.C. "RNA Editing". In Encyclopedia of Life Sciences. 1999; .

Van Mater D, Sowden MP, Cianci J, Sparks JD, Sparks CE, Ballatori N, Smith HC. "Ethanol increases apolipoprotein B mRNA editing in rat primary hepatocytes and McArdle cells." Biochemical and biophysical research communications.. 1998 Nov 18; 252(2):334-9.

Sparks JD, Phung TL, Bolognino M, Cianci J, Khurana R, Peterson RG, Sowden MP, Corsetti JP, Sparks CE. "Lipoprotein alterations in 10- and 20-week-old Zucker diabetic fatty rats: hyperinsulinemic versus insulinopenic hyperglycemia." Metabolism: clinical and experimental.. 1998 Nov 0; 47(11):1315-24.

Sowden MP, Eagleton MJ, Smith HC. "Apolipoprotein B RNA sequence 3' of the mooring sequence and cellular sources of auxiliary factors determine the location and extent of promiscuous editing." Nucleic acids research.. 1998 Apr 1; 26(7):1644-52.

Stewart J, Kozlowski P, Sowden M, Messing E, Smith HC. "A quantitative assay for assessing allelic proportions by iterative gap ligation." Nucleic acids research.. 1998 Feb 15; 26(4):961-6.

Sparks JD, Collins HL, Sabio I, Sowden MP, Smith HC, Cianci J, Sparks CE. "Effects of fatty acids on apolipoprotein B secretion by McArdle RH-7777 rat hepatoma cells." Biochimica et biophysica acta.. 1997 Jul 12; 1347(1):51-61.

Collins, H.L.; Sowden, M.P.; Smith, H.C.; Sparks, J.D. & Sparks, C.E. "ApoB Secreation and mRNA levels are increased in McArdle cells expressing a novel protein factor". Circulation. 1997; 96(8): 3041. Suppl S.

Smith HC, Sowden MP. "Base-modification mRNA editing through deamination--the good, the bad and the unregulated." Trends in genetics : TIG.. 1996 Oct 0; 12(10):418-24.

Marsh JB, Diffenderfer MR, Fisher EA, Sowden M, Dong M, Paterniti JR, Burkey BF. "Effect of experimental nephrosis on hepatic lipoprotein secretion and urinary lipoprotein excretion in rats expressing the human apolipoprotein A-I gene." Journal of lipid research.. 1996 May 0; 37(5):1113-24.

Sowden M, Hamm JK, Spinelli S, Smith HC. "Determinants involved in regulating the proportion of edited apolipoprotein B RNAs." RNA.. 1996 Mar 0; 2(3):274-88.

Sowden M, Hamm JK, Smith HC. "Overexpression of APOBEC-1 results in mooring sequence-dependent promiscuous RNA editing." The Journal of biological chemistry.. 1996 Feb 9; 271(6):3011-7.

Skuse GR, Cappione AJ, Sowden M, Metheny LJ, Smith HC. "The neurofibromatosis type I messenger RNA undergoes base-modification RNA editing." Nucleic acids research.. 1996 Feb 1; 24(3):478-85.

Phung, T.L.; Sowden, M.; Sparks, J.D.; Sparks, C.E. & Smith, H.C. "Regulation of Hepatic ApoB RNA Editing in the Genetically Obese Sucker Rat". Metabolism. 1996; 45(9): 1-4.

Sowden M, Harrison S, Ashfield R, Kingsman AJ, Kingsman SM. "Multiple cooperative interactions constrain BPV-1 E2 dependent activation of transcription." Nucleic acids research.. 1989 Apr 25; 17(8):2959-72.

Stanway CA, Sowden MP, Wilson LE, Kingsman AJ, Kingsman SM. "Efficient activation of transcription in yeast by the BPV1 E2 protein." Nucleic acids research.. 1989 Mar 25; 17(6):2187-96.

Books & Chapters

Chapter Title: In "Topics in Current Genetics"
Book Title: Mammalian C to U Editing
Author List: Smith, H.C.; Wedeking, J.E.; Xie, K. and Sowden, M.P.
Edited By: Grosjean, H:Editor
Published By: Springer-Verlag2005