Mark Edward Mapstone, Ph.D.

Contact Information

Locations

University of California - Irvine
Sprague Hall, Room 318
839 Health Sciences Road
Irvine, CA 92697-3095

Biography

Research

Dr. Mapstone studies cognitive function in health and disease. His research addresses mechanisms of cognitive impairment in neurodegenerative diseases such as Alzheimer's and Parkinson's disease and ways to detect these cognitive changes as early in the course of the disease as possible.

His current work in this area focuses on blood based and electrophysiological biomarker discovery for Alzheimer's and Parkinson's diseases. His research also addresses cognitive effects of treatment for neurological diseases such as deep brain stimulation, stem cell therapy and cognitive training. Dr. Mapstone is a clinical neuropsychologist and his research is integrated into his clinical work.

Credentials

Education

1989
BS | Hobart and William Smith Colleges
Psychology

1990
MA | Boston University
Psychology

1990
Louis Lowy Certificate | Boston University
Gerontology

2000
PhD | Northwestern University The Feinberg School of Medicine
Clinical Psychology

Post-doctoral Training & Residency

08/01/2000 - 08/15/2002
Fellowship in Clinical Neuropsychology at University of Rochester Medical Center

07/01/1999 - 07/30/2000
Internship in Clinical Psychology at Rush-Presbyterian-St Luke's Medical Center

Awards

2006
Excellence in Research Incentive Program Award, University of Rochester

2005
Distinguished Delta Chi Award, The Delta Chi National Fraternity

2004
John Henry Hobart Fellow in Ethics and Social Justice, Hobart College

2004
Keynote Speaker, Charter Day Awards Ceremony, Hobart College

2001
NIH Fellowship, University of Rochester Medical Center

2000
George Yacorzinski Scholar, Northwestern University Medical School

1996 - 1999
University Scholar, The Graduate School, Northwestern University

1993
Merit Award, Department of Brain and Cognitive Sciences, MIT

1990
Psi Chi, National Honor Society in Psychology

1988 - 1989
Dean's List Hobart College

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Publications

Journal Articles

4/16/2015
Chapman RM, Gardner MN, Mapstone M, Dupree HM, Antonsdottir IM. "Memory timeline: Brain ERP C250 (not P300) is an early biomarker of short-term storage." Brain research.. 2015 Apr 16; 1604:74-83. Epub 2015 Jan 30.

12/2014
Lin F, Roiland R, Polesskaya O, Chapman B, Johnson M, Brasch J, Chen DG, Mapstone M. "Fatigability disrupts cognitive processes' regulation of inflammatory reactivity in old age." The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.. 2014 Dec; 22(12):1544-54. Epub 2013 Dec 07.

11/2014
Lin F, Heffner K, Mapstone M, Chen DG, Porsteisson A. "Frequency of mentally stimulating activities modifies the relationship between cardiovascular reactivity and executive function in old age." The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.. 2014 Nov; 22(11):1210-21. Epub 2013 Jul 23.

Books & Chapters

2006
Chapter Title: The Secondary Dementias
Book Title: Dementia in Parkinson's disease and dementia with Lewy Bodies
Author List: Mapstone M..
Edited By: Kurlan R.
Published By: Marcel Dekker 2006 in New York

2004
Chapter Title: Closing the window of attention: Effects on navigational cue use in Alzheimer's disease
Book Title: Vision in Alzheimer's Disease
Author List: Mapstone M.; and Weintraub S. In
Edited By: Cronin-Golomb A.; and Hoff P.
Published By: Karger AG. 2004 in Basel

2000
Chapter Title: Selective Attention Following Unilateral Cerebral Lesions: Evidence for Deficits in Global Distribution of Attention.
Book Title: Dissertation Abstracts International: Section B: the Sciences & Engineering
Author List: Mapstone M.
Published By: US: University Microfilms International 2000

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Videos

Combining Research and Care in URMC Memory Care Program

Could Smart Phones Be Eroding Memory?

SECOND OPINION | Memory Enhancement | PBS

SECOND OPINION | Memory Enhancement | APT | Full Episode

Types of Research in URMC Memory Care Program

URMC Memory Care Program