My clinical interests include the studying the effects of jaundice, nutrition, and environmental toxins on developing nervous system in neonates. My future interests include long-term neurodevelopmental outcome, including language, autism and central auditory processing disorders of premature and late preterm neonates
Dr. Amin's research interests include studying the effects of jaundice, perinatal nutrition specifically iron and vitamin D, and other factors such as trace elements, inflammation, and toxins on developing nervous system in premature and term neonates using auditory brainstem responses, visual evoked responses, and long-term neurodevelopmental outcomes during early childhood. He is NIH-funded to study the effects of jaundice on neurodevelopmental outcomes in preterm and term neonates. In addition, he is investigating the role of hormonal factors on brain development. He is also studying the effects of toxins and nutrition on body mass, bone density index, and dental development in neonates.
He is also studying the role of various nutritional factors including lipids and trace elements on development of cholestasis in premature and term neonates as part of observational studies as well as a clinical trial. He is conducting a randomized clinical trial to evaluate the effects of iron supplementation on brain development in neonates. He has expanded his research in India and is actively involved in building research capacity at participating centers in India. He is also conducting a clinical trial to evaluate the role of chest shielding during phototherapy for prevention of PDA in premature infants. Dr. Amin's future interests include evaluating effect of perinatal factors on long-term neurodevelopmental outcomes such as specific language disorders, cognitive delay, central auditory processing disorders, etc. in premature and late preterm neonates. Also, he is interested in studying genetic mechanisms to determine why there are differences in bilirubin load and susceptibility to bilirubin-induced neurotoxicity. He has been involved in exploring newer techniques to measure free bilirubin levels, a more specific marker of bilirubin-induced neurotoxicity. His work is supported by NICHD, CTSI, and Gerber Foundation.