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Brian Poligone, M.D., Ph.D.

Dermatology

Contact Information

Phone Numbers

Appointment: (585) 275-7546

Appointment: (585) 487-1400

Administrative: (585) 275-3871

Office: (585) 276-4673

Fax: (585) 461-3509

assignmentAccepting New Patients

Biography

Dr. Poligone is an Assistant Professor in the Department of Dermatology at the University of Rochester. He completed his Dermatology training at Yale University, where he developed a special interest in cutaneous lymphoma. He is a member of the Wilmot Cancer Center.

Dr. Poligone directs the Cutaneous Lymphoma clinic at the University of Rochester, which offers an integrated approach to the treatment of all skin lymphomas. This allows for the full evaluation, consultation, and management of B and T cell lymphomas. Current therapies include topical and biologic therapies, infusional and systemic therapies, phototherapy, radiation therapy, photopheresis, and multiple clinical trials for refractory disease.

Research

The Poligone Laboratory studies signal transduction in the skin, specifically examining the role of the transcription factor NF kappa B in skin physiology and disease. Using genetic animal models to study the function of NF kappa B, we strive to better understand the molecular mechanisms behind skin inflammation and carcinogenesis. By studying animal models of disease, we are better able to translate our findings into clinically relevant treatments for human disease. Through his past work with Drs. Albert S. Baldwin and Sankar Ghosh, Dr. Poligone has gained expertise in the study of NF kappa B and has focused his attention to the skin. Currently we are examining how NF kappa B is involved in the formation of a type of skin cancer called a keratoacanthoma. Dr. Poligone has also examined the role of NF kappa B in psoriasis and specifically has been examining NF kappa B inhibitors in this disease.

Credentials

Specialties

  • Dermatology - American Board of Dermatology

Education

1995
B.S., | University of North Carolina Chapel Hill
Biology

2001
Ph.D., | University of North Carolina School of Medicine
Genetics

2003
MD, | University of North Carolina School of Medicine
Medicine

Post-doctoral Training & Residency

07/11/2006 - 04/29/2008
Fellowship in Dermatology at Yale New Haven Hospital

06/25/2003 - 06/24/2004
Internship in Internal Medicine at Stanford University Medical Center

07/01/2004 - 06/30/2007
Residency in Dermatology at Yale New Haven Hospital

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Awards

2008
Dermatology Foundation Career Development Award

2002
www.facultyof1000.com, Journal of Immunology
Location: University of North Carolina School of Medicine

1999 - 1999
National Institutes of Health Summer Research Fellowship
Location: University of North Carolina School of Medicine

1999
American Society of Hematology, Medical Student Fellowship
Location: University of North Carolina School of Medicine

1999
John B. Graham Research Society
Location: University of North Carolina School of Medicine

1998 - 1999
Evaluation of a Hereditary Thrombocytopenia in a Family in Coastal North Carolina
Sponsor: Holderness Medical Fellowship
Location: North Carolina

1994
Class of 1938 Scholar (Summer Study)
Sponsor: UNC Alumni Class
Location: Switzerland

1994
Harrisburg Physicians Scholarship
Location: Harrisburg, Pennsylvania

1993
Howard Hughes Undergraduate Research Grant
Location: Wake Forest University

1992
Eta Sigma Phi (National Classical Studies Honor Society)
Location: Wake Forest University

1988 - 1996
Medical Scientist Training Program (Eight Years Scholarship)
Sponsor: University of North Carolina School of Medicine


Dean's List and Honors in Biology (All Semesters)
Location: University of North Carolina

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Publications

Journal Articles

4/2016
Chen L, Oleksyn D, Pulvino M, Sanz I, Ryan D, Ryan C, Lin CS, Poligone B, Pentland AP, Ritchlin C, Zhao J. "A critical role for the protein kinase PKK in the maintenance of recirculating mature B cells and the development of B1 cells." Immunology letters.. 2016 Apr 0; 172:67-78. Epub 2016 Feb 26.

12/2015
Chung CG, Poligone B. "Cutaneous T cell Lymphoma: an Update on Pathogenesis and Systemic Therapy." Current hematologic malignancy reports.. 2015 Dec 0; 10(4):468-76.

10/2015
Poligone B, Querfeld C. "Management of advanced cutaneous T-cell lymphoma: role of the dermatologist in the multidisciplinary team." The British journal of dermatology.. 2015 Oct 0; 173(4):1081-3. Epub 2015 Aug 27.

Books & Chapters

2007
Book Title: "Springtime Dermatology"
Author List: Poligone, B
Published By: Cortlandt Forum2007

2007
Book Title: "Spider Bites"
Author List: Poligone, B
Published By: Cortlandt Forum2007

2007
Book Title: "Seasonal Dermatoses"
Author List: Poligone, B
Published By: Cortlandt Forum2007

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