Gisela Beutner, Ph.D.

Gisela Beutner, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 631
Rochester, NY 14642

Journal Articles

Showing all 22 journal articles available.

2016 Sep 3
Beutner G, Kambiz AN, Jonas EA, Porter GA. "The Mitochondrial Permeability Transition Pore and ATP Synthase." Handbook of experimental pharmacology. 2016 Sep 3; Epub 2016 Sep 03.
2016 Feb 11
Mnatsakanyan N, Beutner G, Porter GA, Alavian KN, Jonas EA. "Physiological roles of the mitochondrial permeability transition pore." Journal of bioenergetics and biomembranes. 2016 Feb 11; Epub 2016 Feb 11.
Yang YP, Lotta L, Beutner G, Li X, Schor NF. "Induction of Expression of p75 Neurotrophin Receptor Intracellular Domain Does Not Induce Expression or Enhance Activity of Mitochondrial Complex II." Oxidative medicine and cellular longevity. 2016 2016:8752821. Epub 2015 Nov 10.
2015 Sep
Jonas EA, Porter GA, Beutner G, Mnatsakanyan N, Alavian KN. "Cell death disguised: The mitochondrial permeability transition pore as the c-subunit of the F(1)F(O) ATP synthase." Pharmacological research. 2015 Sep; 99:382-92. Epub 2015 May 05.
2014 Jul 22
Alavian KN, Beutner G, Lazrove E, Sacchetti S, Park HA, Licznerski P, Li H, Nabili P, Hockensmith K, Graham M, Porter GA, Jonas EA. "An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore." Proceedings of the National Academy of Sciences of the United States of America. 2014 Jul 22; 111(29):10580-5. Epub 2014 Jun 16.
2014 Jul 11
Jakob R, Beutner G, Sharma VK, Duan Y, Gross RA, Hurst S, Jhun BS, O-Uchi J, Sheu SS. "Molecular and functional identification of a mitochondrial ryanodine receptor in neurons." Neuroscience letters. 2014 Jul 11; 575:7-12. Epub 2014 May 23.
Beutner G, Eliseev RA, Porter GA. "Initiation of electron transport chain activity in the embryonic heart coincides with the activation of mitochondrial complex 1 and the formation of supercomplexes." PloS one. 2014 9(11):e113330. Epub 2014 Nov 26.
Sokolova N, Pan S, Provazza S, Beutner G, Vendelin M, Birkedal R, Sheu SS. "ADP protects cardiac mitochondria under severe oxidative stress." PloS one. 2013 8(12):e83214. Epub 2013 Dec 13.
2011 Jun 17
Ryu SY, Beutner G, Kinnally KW, Dirksen RT, Sheu SS. "Single channel characterization of the mitochondrial ryanodine receptor in heart mitoplasts." The Journal of biological chemistry. 2011 Jun 17; 286(24):21324-9. Epub 2011 Apr 27.
2010 May 17
Ryu SY, Beutner G, Dirksen RT, Kinnally KW, Sheu SS. "Mitochondrial ryanodine receptors and other mitochondrial Ca2+ permeable channels." FEBS letters. 2010 May 17; 584(10):1948-55. Epub 2010 Jan 21.
2009 Oct 2
Kalifa L, Beutner G, Phadnis N, Sheu SS, Sia EA. "Evidence for a role of FEN1 in maintaining mitochondrial DNA integrity." DNA repair. 2009 Oct 2; 8(10):1242-9. Epub 2009 Aug 21.
2007 Jul
Altschafl BA, Beutner G, Sharma VK, Sheu SS, Valdivia HH. "The mitochondrial ryanodine receptor in rat heart: a pharmaco-kinetic profile." Biochimica et biophysica acta. 2007 Jul; 1768(7):1784-95. Epub 2007 Apr 19.
2005 Nov 10
Beutner G, Sharma VK, Lin L, Ryu SY, Dirksen RT, Sheu SS. "Type 1 ryanodine receptor in cardiac mitochondria: transducer of excitation-metabolism coupling." Biochimica et biophysica acta. 2005 Nov 10; 1717(1):1-10. Epub 2005 Oct 11.
2002 Feb
Alano CC, Beutner G, Dirksen RT, Gross RA, Sheu SS. "Mitochondrial permeability transition and calcium dynamics in striatal neurons upon intense NMDA receptor activation." Journal of neurochemistry. 2002 Feb; 80(3):531-8.
2001 Jun 15
Beutner G, Sharma VK, Giovannucci DR, Yule DI, Sheu SS. "Identification of a ryanodine receptor in rat heart mitochondria." The Journal of biological chemistry. 2001 Jun 15; 276(24):21482-8. Epub 2001 Apr 10.
1998 Apr 20
Marzo I, Brenner C, Zamzami N, Susin SA, Beutner G, Brdiczka D, Rémy R, Xie ZH, Reed JC, Kroemer G. "The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins." The Journal of experimental medicine. 1998 Apr 20; 187(8):1261-71.
1998 Jan 5
Beutner G, Rück A, Riede B, Brdiczka D. "Complexes between porin, hexokinase, mitochondrial creatine kinase and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases." Biochimica et biophysica acta. 1998 Jan 5; 1368(1):7-18.
Brdiczka D, Beutner G, Rück A, Dolder M, Wallimann T. "The molecular structure of mitochondrial contact sites. Their role in regulation of energy metabolism and permeability transition." BioFactors (Oxford, England). 1998 8(3-4):235-42.
1997 Sep 8
O'Gorman E, Beutner G, Dolder M, Koretsky AP, Brdiczka D, Wallimann T. "The role of creatine kinase in inhibition of mitochondrial permeability transition." FEBS letters. 1997 Sep 8; 414(2):253-7.
1997 Feb
Beutner G, Rück A, Riede B, Brdiczka D. "Complexes between hexokinase, mitochondrial porin and adenylate translocator in brain: regulation of hexokinase, oxidative phosphorylation and permeability transition pore." Biochemical Society transactions. 1997 Feb; 25(1):151-7.
1996 Nov 4
Beutner G, Ruck A, Riede B, Welte W, Brdiczka D. "Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore." FEBS letters. 1996 Nov 4; 396(2-3):189-95.
1996 Sep 12
O'Gorman E, Beutner G, Wallimann T, Brdiczka D. "Differential effects of creatine depletion on the regulation of enzyme activities and on creatine-stimulated mitochondrial respiration in skeletal muscle, heart, and brain." Biochimica et biophysica acta. 1996 Sep 12; 1276(2):161-70.